Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sabine Klöppner"'
Publikováno v:
Journal of Molecular Neuroscience. 35:65-79
Oligodendrocytes met neurotrophins in the early 1990s of the last century. Since then, their relationship underwent functional ups and downs partially dependent on the developmental stage of the oligodendroglial cells and the species, from which the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ff95a58de3991b20a4cc77a77e837b
https://doi.org/10.1007/s12031-008-9053-y
https://doi.org/10.1007/s12031-008-9053-y
Autor:
Wolfgang Holtz, Gerlinde Rohde, H. H. Althaus, Wolfgang Brück, Sabine Klöppner, Nahid Parvizi, Peter Schwartz
Publikováno v:
Neuroscience Letters. 283:77-80
Two methods prevail at present in producing demyelinated areas in the central nervous system. One uses the detergent-like effect of lysolecithin, the other is based on a cell killing effect of ethidium bromide plus x-irradiation. Unwanted side-effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a65d79252e5ab23afa215143276070
https://doi.org/10.1016/s0304-3940(00)00920-4
https://doi.org/10.1016/s0304-3940(00)00920-4
Publikováno v:
Neuroscience Letters. 135:219-223
Mature oligodendrocytes (OL) isolated from adult pig brains start to regenerate their fibers after 4–5 days in vitro (DIV); after 14 DIV a network of OL fibers is formed. Growth factors, of which it was known that they play an important part during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b1cd4b9423df8e3d28aea4bf626677
https://doi.org/10.1016/0304-3940(92)90440-i
https://doi.org/10.1016/0304-3940(92)90440-i
Autor:
Sabine Klöppner, Wiebke Möbius, Steve Klopfleisch, H. H. Althaus, Inga Zerr, Matthias Schmitz, Peter Schwartz
Publikováno v:
Journal of Neuroscience Research.
Signaling of growth factors may depend on the recruitment of their receptors to specialized microdomains. Previous reports on PC12 cells indicated an interaction of raft-organized caveolin and TrkA signaling. Because porcine oligodendrocytes (OLs) re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34d16f7d7b14a71a969c967365d9a79
https://doi.org/10.1002/jnr.22235
https://doi.org/10.1002/jnr.22235
Autor:
J. Schröter, H. H. Althaus, P. E. Spoerri, Sabine Klöppner, A. Rohmann, Peter Schwartz, Volker Neuhoff
Publikováno v:
Journal of Neuroscience Research. 29:481-489
Oligodendrocytes (OL) isolated from adult pig brains regenerate their processes and form a network of fibers after 14-18 days in vitro (DIV). Stimulation of protein kinase C (Pk-C) by tumour promoters such as 12-O-tetradecanoylphorbol-13-acetate (TPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368aa2766a8e035585d7691fddcd4105
https://doi.org/10.1002/jnr.490290408
https://doi.org/10.1002/jnr.490290408
Autor:
Wolfgang Brück, Mariann Schedensack, Sabine Klöppner, Steve Klopfleisch, Matthias Schmitz, Gunnar Jeserich, Doron Merkler, H. H. Althaus
Publikováno v:
Journal of Neuroscience, Vol. 28, No 50 (2008) pp. 13609-13614
Statins are widely prescribed drugs in cardiovascular diseases. Recent studies also demonstrated anti-inflammatory and immunomodulatory properties of statins by modulating the activity of small GTPases. Statins are thus considered as potential therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e6244327c22a0a0dc261d4b707723f
https://archive-ouverte.unige.ch/unige:19150
https://archive-ouverte.unige.ch/unige:19150
Autor:
H. H. Althaus, Sabine Klöppner
Publikováno v:
Journal of neurochemistry. 98(2)
The neurotrophin family with its first member, nerve growth factor (NGF), binds two classes of receptors, more specifically to Trk receptors and to a shared p75NTR receptor. It has been shown that proNGF rather than NGF is predominant in the mature c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c710f1bcfa7b59d04c76a2928adbd6e
https://pubmed.ncbi.nlm.nih.gov/16805842
https://pubmed.ncbi.nlm.nih.gov/16805842
Autor:
Hempel R, Tyede Schmidt-Schultz, Kruska L, Rolf Heumann, Engel J, Sabine Klöppner, H. H. Althaus
Publikováno v:
Journal of neuroscience research. 50(5)
It has previously been shown that nerve growth factor (NGF) is of functional significance for mature pig oligodendrocytes (OLs) in culture. The present data give evidence for the expression of TrkA, the so-called high-affinity NGF receptor, and of p7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55a87e833eaf2bbc7c546ec8608d688
https://pubmed.ncbi.nlm.nih.gov/9418961
https://pubmed.ncbi.nlm.nih.gov/9418961
Publikováno v:
Molecular Signaling and Regulation in Glial Cells ISBN: 9783642645013
Recently, it was shown that NGF enhances the process regeneration of mature pig oligodendrocytes (OL) and that it induces a subset of mature OL to proliferate. This effect is mediated by TrkA, the NGF tyrosine kinase receptor. Astrocytes belong to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4647c93b28c4bf91c80ddc7b5624168
https://doi.org/10.1007/978-3-642-60669-4_3
https://doi.org/10.1007/978-3-642-60669-4_3
Publikováno v:
Cellular and Molecular Biology of Myelination ISBN: 9783642839702
Oligodendrocytes (Ol), shorn of their processes during the isolation procedure, regenerate their fibres under appropriate culture conditions (Althaus et al., 1984). various diffusible and non-diffusible compounds contribute to this regenerative proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b47f69fb3eedc3a2702c76941ef34a91
https://doi.org/10.1007/978-3-642-83968-9_17
https://doi.org/10.1007/978-3-642-83968-9_17