Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sabine J. Wölfle"'
Autor:
Katharina Giesbrecht, Mariel-Esther Eberle, Sabine J. Wölfle, Delal Sahin, Aline Sähr, Valerie Oberhardt, Zach Menne, Konrad A. Bode, Klaus Heeg, Dagmar Hildebrand
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
During infection pathogen-associated molecular patterns activate immune cells to initiate a cascade of reactions leading to inflammation and the activation of the adaptive immune response culminating in the elimination of foreign pathogens. However,
Externí odkaz:
https://doaj.org/article/18a228181dda4a62bde0964f29f534dd
Autor:
Sabine J. Wölfle, Julia S. Frick, Andre Fischer, Sarah Menz, Melanie R. Shakespear, Judith Knievel, Julian David Langer, Liliana Schaefer, Dominik Stammler, Konrad A. Bode, Jonathan Jantsch, Klaus Heeg, Ina Oehme, Tatjana Eigenbrod, Isabel Siegert, Alexander H. Dalpke, Matthew J. Sweet
Publikováno v:
The journal of immunology 195(11), 5421-5431 (2015). doi:10.4049/jimmunol.1501195
Histone deacetylase (HDAC) inhibitors (HDACi) are clinically approved anticancer drugs that have important immune-modulatory properties. We report the surprising finding that HDACi promote LPS-induced IL-1β processing and secretion in human and muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d790a8a880fbfadefa2bda86ca77cda
https://doi.org/10.4049/jimmunol.1501195
https://doi.org/10.4049/jimmunol.1501195
Autor:
Caroline Arnold, Klaus Heeg, Julia Strebovsky, Aline Sahr, Holger Bartz, Claus Kaiser, Alexander H. Dalpke, Sabine J. Wölfle
Publikováno v:
European Journal of Immunology. 41:413-424
During infection, TLR agonists are released and trigger mature as well as differentiating innate immune cells. Early encounter with TLR agonists (R848; LPS) blocks conventional differentiation of CD14(+) monocytes into immature dendritic cells (iDCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26aad4028df57c6ed5338f6c4c7a190c
https://doi.org/10.1002/eji.201040979
https://doi.org/10.1002/eji.201040979
Publikováno v:
Cell Communication and Signaling, Vol 10, Iss 1, p 22 (2012)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Lipopolysaccharide (LPS)-triggered Toll-like receptor (TLR) 4-signalling belongs to the key innate defence mechanisms upon infection with Gram-negative bacteria and triggers the subsequent activation of adaptive immunity. There is an activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ba87607d4d2c2f63d291237f4539ac
http://www.biosignaling.com/content/10/1/22
http://www.biosignaling.com/content/10/1/22