CIRS-LAS – a novel approach to increase transparency in laboratory animal science for improving animal welfare by reducing laboratory animal distress

Autor: Astrid Enkelmann, Sabine J. Bischoff

Publikováno v: Frontiers in Veterinary Science, Vol 10 (2023)

The 3Rs principle is highly topical in animal-based research. These include, above all, new scientific methods for conducting experiments without an animal model, by using non-animal models (Replace), reducing the number of laboratory animals (Reduct

Externí odkaz: https://doaj.org/article/739d82f6c4d644c7a6ec21e2b8b4c064

Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model

Autor: Schmidt, René Schiffner, Sabine J. Bischoff, Thomas Lehmann, Andrey Irintchev, Marius Nistor, Cornelius Lemke, Martin

Publikováno v: International Journal of Molecular Sciences; Volume 21; Issue 5; Pages: 1632

Specific neuroprotective strategies to minimize cerebral damage caused by severe hypoxia or hypovolemia are lacking. Based on previous studies showing that relaxin-2/serelaxin increases cortical cerebral blood flow, we postulated that serelaxin might

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::6b568122bd3dc2482603f75ead056343

Renal glucose release during hypoglycemia is partly controlled by sympathetic nerves - a study in pigs with unilateral surgically denervated kidneys.

Autor: Bischoff, Sabine J.¹, Schmidt, Martin², Lehmann, Thomas³, Schwab, Matthias⁴, Matziolis, Georg⁵, Saemann, Alexander⁶, Schiffner, René^4,5

Publikováno v: Physiological Reports. Nov2015, Vol. 3 Issue 11, p1-N.PAG. 10p.

Altered Cerebral Blood Flow and Potential Neuroprotective Effect of Human Relaxin-2 (Serelaxin) During Hypoxia or Severe Hypovolemia in a Sheep Model.

Autor: Schiffner, René^1,2 (AUTHOR) rene.schiffner@med.ovgu.de, Bischoff, Sabine J.³ (AUTHOR) sabine.bischoff@med.uni-jena.de, Lehmann, Thomas⁴ (AUTHOR) thomas.lehmann@med.uni-jena.de, Irintchev, Andrey⁵ (AUTHOR) andrey.irintchev@med.uni-jena.de, Nistor, Marius² (AUTHOR), Lemke, Cornelius⁶ (AUTHOR) cornelius.lemke@med.uni-jena.de, Schmidt, Martin⁷ (AUTHOR) martin.schmidt@med.uni-jena.de

Publikováno v: International Journal of Molecular Sciences. Mar2020, Vol. 21 Issue 5, p1632. 1p. 13 Graphs.

Laryngeal pacing in minipigs: in vivo test of a new minimal invasive transcricoidal electrode insertion method for functional electrical stimulation of the PCA.

Autor: Förster, Gerhard, Arnold, Dirk, Bischoff, Sabine J., Schubert, Harald, Scholle, Hans-Christoph, Müller, Andreas H.

Publikováno v: European Archives of Oto-Rhino-Laryngology; Jan2013, Vol. 270 Issue 1, p225-231, 7p, 3 Color Photographs, 1 Black and White Photograph, 2 Diagrams, 3 Charts