Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sabine Jörg"'
Autor:
Franca Del Nonno, Ellen Heinemann, Maura Farinacci, Kellen C. Faé, Delia Goletti, Rosanna Capparelli, Jörg Schreiber, Sabine Jörg, Pedro Moura-Alves, Dagmar Oberbeck-Müller, Marco Iannaccone, Anca Dorhoi, Delia Löwe, Hans-Joachim Mollenkopf, Karin Hahnke, Geraldine Nouailles, Stefan H. E. Kaufmann
The molecular mechanisms that control innate immune cell trafficking during chronic infection and inflammation, such as in tuberculosis (TB), are incompletely understood. During active TB, myeloid cells infiltrate the lung and sustain local inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc39e66c39d4419e106cf48ce637b61a
https://doi.org/10.1172/jci67604
https://doi.org/10.1172/jci67604
Autor:
Sabine Jörg, Lydia Pradl, Jürg Tschopp, Dagmar Oberbeck-Müller, Anca Dorhoi, Olaf Gross, Geraldine Nouailles, Roland Brosch, María A. Duque-Correa, Jürgen Ruland, Stephen T. Reece, Ellen Heinemann, Stefan H. E. Kaufmann, Kristine Hagens
Publikováno v:
European Journal of Immunology. 42:374-384
As a hallmark of tuberculosis (TB), Mycobacterium tuberculosis (MTB) induces granulomatous lung lesions and systemic inflammatory responses during active disease. Molecular regulation of inflammation is associated with inflammasome assembly. We deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88b0155a584e4ee6ebfa445734ba56a7
https://doi.org/10.1002/eji.201141548
https://doi.org/10.1002/eji.201141548
Autor:
George A. Kosmiadi, Sabine Jörg, Pia Gamradt, Robert Hurwitz, Geraldine Nouailles, Stefanie Kuhlmann, Stephen T. Reece, Mischo Kursar, Hans-Joachim Mollenkopf, Marc Jacobsen, Stefan H. E. Kaufmann, Markus Koch, Delia Miekley, Tracey A. Day
Publikováno v:
European Journal of Immunology. 40:1663-1673
Tuberculosis causes 2 million deaths per year, yet in most cases the immune response successfully contains the infection and prevents disease outbreak. Induced lymphoid structures associated with pulmonary granuloma are observed during tuberculosis i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2a7e15bf69cd6a74e58fb1da0a300b
https://doi.org/10.1002/eji.201040299
https://doi.org/10.1002/eji.201040299
Autor:
Sabine Jörg, Roland Krause, Jörg Schreiber, Sang Nae Cho, Bo Young Jeon, Juan Pablo Patron, Jeong Yeon Kwak, Hans-Joachim Mollenkopf, Jane Kowall, Jong Seok Lee, Robert Stein, Min Kyong Song, Stefan H. E. Kaufmann, Kyoung-Min Roh
Publikováno v:
Cell Host & Microbe. 3(2):97-103
SummaryAttenuated strains of mycobacteria can be exploited to determine genes essential for their pathogenesis and persistence. To this goal, we sequenced the genome of H37Ra, an attenuated variant of Mycobacterium tuberculosis H37Rv strain. Comparis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6479f8474e553e22add1e6b55e479f9
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 263:195-198
Myxoid chondrosarcomas of the head and neck region are rare. We report the case of an 8-year-old boy with progressive unilateral nasal obstruction resulting from a highly differentiated myxoid chondrosarcoma of the maxilla extending to the nasal cavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be86ab784f6d0c5bea56d8d2079a5b18
https://doi.org/10.1007/s00405-005-0981-7
https://doi.org/10.1007/s00405-005-0981-7
Autor:
Sabine Jörg, Vladimir Mishenko, Timo Ulrichs, Lydia Pradl, George A. Kosmiadi, Nadya Gushina, Stefan H. E. Kaufmann, Marina Titukhina
Publikováno v:
The Journal of Infectious Diseases. 192:89-97
Background. In 90% of all cases, Mycobacterium tuberculosis infection results in latency rather than active disease, with the pathogen being contained within granulomatous lesions at the site of primary infection. Failure of this containment leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f47298b7e838178f0ef08fb9c99c01
https://doi.org/10.1086/430621
https://doi.org/10.1086/430621
Autor:
Vsevolod Trusov, Stefan H. E. Kaufmann, Timo Ulrichs, George A. Kosmiadi, Vladimir Mishenko, Sabine Jörg, Marina Titukhina, Nadya Gushina, Lydia Pradl
Publikováno v:
The Journal of Pathology. 204:217-228
The human tuberculous granuloma provides the morphological basis for local immune processes central to the outcome of tuberculosis. Because of the scarcity of information in human patients, the aim of the present study was to gain insights into the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1b1fe299dabba9896b2de1311ab756
https://doi.org/10.1002/path.1628
https://doi.org/10.1002/path.1628
Autor:
Karin Hahnke, Sabine Jörg, Julia K. Knaul, Geraldine Nouailles, Hans-Joachim Mollenkopf, Ellen Heinemann, Stefan H. E. Kaufmann, Alexis Vogelzang, Dagmar Oberbeck-Müller, Volker Brinkmann, Anca Dorhoi, January Weiner, Stephen T. Reece, Vladimir Yeremeev
Publikováno v:
European Journal of Immunology
General interest in the biological functions of IFN type I in Mycobacterium tuberculosis (Mtb) infection increased after the recent identification of a distinct IFN gene expression signature in tuberculosis (TB) patients. Here, we demonstrate that TB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7942af911c261f20f785a7c3ce472d8e
https://pubmed.ncbi.nlm.nih.gov/24782112
https://pubmed.ncbi.nlm.nih.gov/24782112
Autor:
Tracey A. Day, Mischo Kursar, Geraldine Nouailles, Markus Koch, Pia Gamradt, Robert Hurwitz, Stefan H. E. Kaufmann, Stefanie Kuhlmann, Lydia Pradl, Anca Dorhoi, Sabine Jörg, Delia Loewe, Andreas Hutloff
Publikováno v:
European journal of immunology. 41(4)
Even though Mycobacterium tuberculosis (Mtb) remains one of the top microbial killers, more than 90% of the 2 billion infected individuals never develop active tuberculosis (TB), indicating efficient immune control of infection in these individuals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5718f08a453955bff8c109368102019d
https://pubmed.ncbi.nlm.nih.gov/21337542
https://pubmed.ncbi.nlm.nih.gov/21337542