Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sabine Hummert"'
Autor:
Jana Schirmeyer, Thomas Eick, Eckhard Schulz, Sabine Hummert, Christian Sattler, Ralf Schmauder, Klaus Benndorf
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 8, p e1010376 (2022)
Cyclic nucleotide-gated (CNG) ion channels of olfactory sensory neurons contain three types of homologue subunits, two CNGA2 subunits, one CNGA4 subunit and one CNGB1b subunit. Each subunit carries an intracellular cyclic nucleotide binding domain (C
Externí odkaz:
https://doaj.org/article/ebc7e5e9eecf4c9593cc5cb6b7fb22cd
Autor:
Christian Sattler, Thomas Eick, Sabine Hummert, Eckhard Schulz, Ralf Schmauder, Andrea Schweinitz, Christopher Unzeitig, Frank Schwede, Klaus Benndorf
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Ionotropic purinergic (P2X) receptors are trimeric channels that are activated by the binding of ATP. They are involved in multiple physiological functions, including synaptic transmission, pain and inflammation. The mechanism of activation
Externí odkaz:
https://doaj.org/article/1df92b225dd244dcb0623e62c017f5d8
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006045 (2018)
Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control electrical rhythmicity in specialized brain and heart cells. We quantitatively analysed voltage-dependent activation of homotetrameric HCN2 channels and its modulation by
Externí odkaz:
https://doaj.org/article/c082d95355f5469fb9645193c93d5ed5
Autor:
Eckhard Schulz, Michele Bonus, Christian Sattler, Thomas Zimmer, Melanie Wiegand, Ralf Schmauder, Klaus Benndorf, Nisa Kosmalla, Holger Gohlke, Taulant Kukaj, Thomas Eick, Gunter Ehrlich, Tina Schwabe, Jan L. Münch, Jana Schirmeyer, Sabine Hummert
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 118(30), e2100469118 (2021). doi:10.1073/pnas.2100469118
Proceedings of the National Academy of Sciences of the United States of America 118(30), e2100469118 (2021). doi:10.1073/pnas.2100469118
Significance Membrane receptors control innumerous essential functions of living cells and are proven drug targets for pharmacological interventions. Many receptors are composed of a number of subunits and contain multiple binding sites for ligands,
Autor:
Nisa Wongsamitkul, Thomas Eick, Eckhard Schulz, Thomas Zimmer, Ralf Schmauder, Jana Schirmeyer, Sabine Hummert, Vasilica Nache, Klaus Benndorf
Publikováno v:
Scientific Reports. 8
Scientific Reports 6; Article number: 20974; published online: 09 February 2016; updated: 28 June 2018 The Acknowledgements section in this Article is incomplete. “We would like to thank G. Ditze, G. Sammler, F. Horn, M. Händel, K. Schoknecht, S.
Playing ‘hide-and-seek’ with factor H: game-theoretical analysis of a single nucleotide polymorphism
Autor:
Christian Hummert, Stefan Schuster, Peter F. Zipfel, Sebastian Germerodt, Stefan N. Lang, Christina Glock, Sabine Hummert, Christine Skerka
As a part of the complement system, factor H regulates phagocytosis and helps differentiate between a body's own and foreign cells. Owing to mimicry efforts, some pathogenic microorganisms such as Candida albicans are able to bind factor H on their c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db823d21448e14dcb72b5c9f67e37856
https://europepmc.org/articles/PMC6000180/
https://europepmc.org/articles/PMC6000180/
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006045 (2018)
PLoS Computational Biology
PLoS Computational Biology
Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control electrical rhythmicity in specialized brain and heart cells. We quantitatively analysed voltage-dependent activation of homotetrameric HCN2 channels and its modulation by
Autor:
Katrin Bohl, Stefan Schuster, Anja Schroeter, Sarah Werner, David Basanta, Andreas Deutsch, Günter Theißen, Sabine Hummert
Publikováno v:
Mol. BioSyst.. 10:3066-3074
In this and an accompanying paper we review the use of game theoretical concepts in cell biology and molecular biology. This review focuses on the subcellular level by considering viruses, genes, and molecules as players. We discuss in which way cata
Publikováno v:
Journal of Theoretical Biology. 264:312-318
The polymorphic fungus Candida albicans can live as an aggressive pathogen that causes a wide variety of diseases in humans. Host resistance against these infections is mediated predominantly by phagocytes, namely neutrophils and macrophages. This re
Autor:
Katrin Bohl, Sabine Hummert, Andreas Deutsch, David Basanta, Günter Theißen, Sarah Werner, Anja Schroeter, Stefan Schuster
Publikováno v:
Molecular bioSystems. 10(12)
In two papers we review game theory applications in biology below the level of cognitive living beings. It can be seen that evolution and natural selection replace the rationality of the actors appropriately. Even in these micro worlds, competing sit