Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sabine Herblot"'
Autor:
Nicolas Poirier, Elie Haddad, Michel Duval, Valérie Paquin, Séverine Leclerc, Véronique Lisi, Carolina Marmolejo, Hicham Affia, Paulo Cordeiro, Yves Théorêt, Gregor Andelfinger, Vincent Philippe Lavallée, Sabine Herblot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Allogeneic hematopoietic stem cell transplantation (HSCT) remains the standard of care for chemotherapy-refractory leukemia patients, but cure rates are still dismal. To prevent leukemia relapse following HSCT, we aim to improve the early
Externí odkaz:
https://doaj.org/article/f0f0716f6dc24b4b8ba472b368e8d196
Autor:
Diogo F. T. Veiga, Mathieu Tremblay, Bastien Gerby, Sabine Herblot, André Haman, Patrick Gendron, Sébastien Lemieux, Juan Carlos Zúñiga-Pflücker, Josée Hébert, Joseph Paul Cohen, Trang Hoang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Early T-cell development is precisely controlled by E proteins, that indistinguishably include HEB/TCF12 and E2A/TCF3 transcription factors, together with NOTCH1 and pre-T cell receptor (TCR) signalling. Importantly, perturbations of early T-cell reg
Externí odkaz:
https://doaj.org/article/f03cd79bc764496da7d5dad1fdaa2f3b
Autor:
Martine Cordeau, Assila Belounis, Martin Lelaidier, Paulo Cordeiro, Hervé Sartelet, Sabine Herblot, Michel Duval
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164401 (2016)
High-risk neuroblastoma (NB) remains a major therapeutic challenge despite the recent advent of disialoganglioside (GD2)-antibody treatment combined with interleukin (IL)-2 and granulocyte monocyte-colony stimulating factor (GM-CSF). Indeed, more tha
Externí odkaz:
https://doaj.org/article/d1b46bbb788f43dcaf847661ee11ffdd
Autor:
Bastien Gerby, Cedric S Tremblay, Mathieu Tremblay, Shanti Rojas-Sutterlin, Sabine Herblot, Josée Hébert, Guy Sauvageau, Sébastien Lemieux, Eric Lécuyer, Diogo F T Veiga, Trang Hoang
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004768 (2014)
The molecular determinants that render specific populations of normal cells susceptible to oncogenic reprogramming into self-renewing cancer stem cells are poorly understood. Here, we exploit T-cell acute lymphoblastic leukemia (T-ALL) as a model to
Externí odkaz:
https://doaj.org/article/b02922aa59b74cc7982008ea73a621e7
Autor:
Diogo F T, Veiga, Mathieu, Tremblay, Bastien, Gerby, Sabine, Herblot, André, Haman, Patrick, Gendron, Sébastien, Lemieux, Juan Carlos, Zúñiga-Pflücker, Josée, Hébert, Joseph Paul, Cohen, Trang, Hoang
Publikováno v:
Frontiers in immunology. 13
Early T-cell development is precisely controlled by E proteins, that indistinguishably include HEB/TCF12 and E2A/TCF3 transcription factors, together with NOTCH1 and pre-T cell receptor (TCR) signalling. Importantly, perturbations of early T-cell reg
Autor:
Sabine Herblot, Marie-Eve Laliberté-Gagné, Marilène Bolduc, Denis Leclerc, Damien Carignan, Pierre Savard, Michel Duval
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 14:2317-2327
Rod-shaped virus-like nanoparticles (VLNP) made of papaya mosaic virus (PapMV) coat proteins (CP) self-assembled around a single stranded RNA (ssRNA) were showed to be a TLR7 agonist. Their utilization as an immune modulator in cancer immunotherapy w
Autor:
Assila Belounis, Paulo Cordeiro, Sabine Herblot, Elie Haddad, Pierre Teira, Michel Duval, William Lemieux, Marina Ayoub
Publikováno v:
Cancer immunology, immunotherapy : CII. 69(9)
Targeted immunotherapy has improved the outcome of patients with high-risk neuroblastoma (NB). However, immune escape of tumor cells still occurs and about 40% of NB patients relapse and die from their disease. We previously showed that natural kille
Publikováno v:
Cancer Immunology, Immunotherapy
Acute lymphoblastic leukemia (ALL) is believed to be resistant to NK cell-mediated killing. To overcome this resistance, we developed an innovative approach based on NK cell stimulation with Toll-like receptor (TLR)-activated plasmacytoid dendritic c
Autor:
Herve Sartelet, Martine Cordeau, Mona Beaunoyer, Sonia Cournoyer, Pierre Teira, Sabine Herblot, Michel Duval, Michel Peuchmaur, Tatjana Terzic
Publikováno v:
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 21(4)
Neuroblastoma, a malignant neoplasm of the sympathetic nervous system, is one of the most aggressive pediatric cancers. Patients with stage IV high-risk neuroblastoma receive an intensive multimodal therapy ending with an immunotherapy based on a chi
Autor:
Paulo Cordeiro, Michel Duval, Sabine Herblot, Martin Lelaidier, Yildian Díaz-Rodríguez, Elie Haddad, Martine Cordeau
Publikováno v:
Oncotarget
Acute lymphoblastic leukemia (ALL) still frequently recurs after hematopoietic stem cell transplantation (HSCT), underscoring the need to improve the graft-versus-leukemia (GvL) effect. Natural killer (NK) cells reconstitute in the first months follo