Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure

Autor: Nikola, Kozhuharov, Assen, Goudev, Dayana, Flores, Micha T, Maeder, Joan, Walter, Samyut, Shrestha, Danielle Menosi, Gualandro, Mucio Tavares, de Oliveira Junior, Zaid, Sabti, Beat, Müller, Markus, Noveanu, Thenral, Socrates, Ronny, Ziller, Antoni, Bayés-Genís, Alessandro, Sionis, Patrick, Simon, Eleni, Michou, Samuel, Gujer, Tommaso, Gori, Philip, Wenzel, Otmar, Pfister, David, Conen, Ioannis, Kapos, Richard, Kobza, Hans, Rickli, Tobias, Breidthardt, Thomas, Münzel, Paul, Erne, Christian, Mueller, Micha, Maeder, Mucio, Tavares de Oliveira, Bojidar, Dimov, Sabine, Hartwiger, Nisha, Arenja, Bettina, Glatz, Natascha, Herr, Rahel, Isenrich, Tamina, Mosimann, Raphael, Twerenbold, Jasper, Boeddinghaus, Thomas, Nestelberger, Christian, Puelacher, Michael, Freese, Janine, Vögele, Kathrin, Meissner, Jasmin, Martin, Ivo, Strebel, Desiree, Wussler, Carmela, Schumacher, Stefan, Osswald, Fabian, Vogt, Jonas, Hilti, Sara, Barata, Deborah, Schneider, Jonas, Schwarz, Brigitte, Fitze, Katharina, Rentsch, Aline, Bossa, Sergio, Jallad, Alexandre, Soeiro, Dimitar, Georgiev, Thomas, Jansen, Gabriele, Gebel, Matthias, Bossard, Michael, Christ

Publikováno v: JAMA. 322:2292

Importance Short-term infusions of single vasodilators, usually given in a fixed dose, have not improved outcomes in patients with acute heart failure (AHF). Objective To evaluate the effect of a strategy that emphasized early intensive and sustained

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62e22d8d3fbf14054e8a0b60ce4ee9a
https://doi.org/10.1001/jama.2019.18598

Comparison of midregional pro-atrial natriuretic peptide with N-terminal pro-B-type natriuretic 
 peptide in the diagnosis of heart failure

Autor: Anne B. Taegtmeyer, Roland Bingisser, Tobias Reichlin, Heike Freidank, Mihael Potocki, Christian Mueller, Markus Noveanu, Tobias Breidthardt, K. Wetzel, Claudia Stelzig, Nils G. Morgenthaler, Sabine Hartwiger, Michael Christ, Tujana Boldanova, Andreas Bergmann

Publikováno v: Journal of Internal Medicine. 267:119-129

Objectives. The concentration of atrial natriuretic peptide (ANP) in the circulation is approximately 10- to 50- fold higher than B-type natriuretic peptide (BNP). We sought to compare the accuracy of midregional pro-atrial natriuretic peptide (MRpro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6417f16d8bdc9a9815f871d6997f9ac3
https://doi.org/10.1111/j.1365-2796.2009.02135.x

Early diagnosis of myocardial infarction with sensitive cardiac troponin assays

Autor: Katrin Winkler, Stefano Bassetti, Claudia Stelzig, Stefan Biedert, Roland Bingisser, Tobias Reichlin, Willibald Hochholzer, Raphael Twerenbold, Markus Noveanu, Nora Schaub, Christine Buerge, Christian Mueller, Tobias Breidthardt, Stephan Steuer, Sabine Hartwiger, Mihael Potocki

Publikováno v: The New England journal of medicine. 361(9)

The rapid and reliable diagnosis of acute myocardial infarction is a major unmet clinical need.We conducted a multicenter study to examine the diagnostic accuracy of new, sensitive cardiac troponin assays performed on blood samples obtained in the em

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489bdcf8228415761b621ccf3d223b85
https://pubmed.ncbi.nlm.nih.gov/30617128

Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Failure: The GALACTIC Randomized Clinical Trial.

Autor: Kozhuharov N; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Goudev A; Queen Ioanna University Hospital Sofia, Department of Cardiology, Medical University of Sofia, Sofia, Bulgaria., Flores D; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Maeder MT; Department of Cardiology, Kantonsspital St Gallen, St Gallen, Switzerland., Walter J; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy.; Department of Internal Medicine, University Hospital Basel, University of Basel, Basel, Switzerland., Shrestha S; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy.; Department of Internal Medicine, University Hospital Basel, University of Basel, Basel, Switzerland., Gualandro DM; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy.; Heart Institute (INCOR), University of Sao Paulo Medical School, Sao Paulo, Brazil., de Oliveira Junior MT; Heart Institute (INCOR), University of Sao Paulo Medical School, Sao Paulo, Brazil., Sabti Z; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Müller B; Department of General Internal and Emergency Medicine, Medical University Clinic of the University of Basel, Kantonsspital Aarau, Aarau, Switzerland., Noveanu M; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Socrates T; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy.; Medical Outpatient Department, University Hospital Basel, University of Basel, Basel, Switzerland., Ziller R; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Bayés-Genís A; Heart Institute, Hospital Universitari Germans Trias i Pujol, CIBERCV, Department of Medicine, Autonomous University of Barcelona, Barcelona, Spain., Sionis A; Intensive Cardiac Care Unit, Cardiology Department, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute IIB-Sant Pau, Autonomous University of Barcelona, Barcelona, Spain., Simon P; Clinical Trial Unit, University Hospital Basel, Basel, Switzerland., Michou E; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Gujer S; Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland.; Department of Internal Medicine, Kantonsspital Obwalden, Sarnen, Switzerland., Gori T; University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Wenzel P; University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Pfister O; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Conen D; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy.; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Kapos I; Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland.; Department of Cardiology, University Hospital Zurich, Zurich, Switzerland., Kobza R; Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland., Rickli H; Department of Cardiology, Kantonsspital St Gallen, St Gallen, Switzerland., Breidthardt T; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy.; Department of Internal Medicine, University Hospital Basel, University of Basel, Basel, Switzerland., Münzel T; University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany., Erne P; Department of Cardiology, Luzerner Kantonsspital, Luzern, Switzerland., Mueller C; Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland.; GREAT Research Network, Rome, Italy., Mueller, Erne, Müller, Rickli, Maeder, Tavares de Oliveira Jr, Münzel, Bayés-Genís, Sionis, Goudev, Dimov, Hartwiger, Arenja N, Glatz, Herr, Isenrich, Mosimann, Twerenbold, Boeddinghaus, Nestelberger, Puelacher, Freese, Vögele, Meissner, Martin, Strebel, Wussler, Schumacher, Osswald, Vogt, Hilti, Barata, Schneider, Schwarz, Fitze, Hartwiger, Arenja, Glatz, Herr, Isenrich, Mosimann, Twerenbold, Boeddinghaus, Nestelberger, Puelacher, Freese, Vögele, Meissner, Martin, Strebel, Wussler, Schumacher, Osswald, Vogt, Hilti, Barata, Schneider, Schwarz, Fitze, Arenja, Rentsch, Bossa, Jallad, Soeiro, Georgiev, Jansen, Gebel, Bossard, Christ

Publikováno v: JAMA [JAMA] 2019 Dec 17; Vol. 322 (23), pp. 2292-2302.