Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sabine Gorynia"'
Publikováno v:
Cancer Research. 79:LB-317
The tumor microenvironment (TME) constitutes unique surroundings where cancer cells communicate with one another and with the host immune system by releasing a multitude of factors. Information about the physiological state of the TME can help in gai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792b925927b162665743a41f9faf1d98
https://doi.org/10.1158/1538-7445.am2019-lb-317
https://doi.org/10.1158/1538-7445.am2019-lb-317
Autor:
Gregory S. Payne, Giancarlo Costaguta, Sabine Gorynia, Duilio Cascio, Lydia Daboussi, Todd C. Lorenz
Publikováno v:
Molecular biology of the cell, vol 23, iss 22
Molecular Biology of the Cell
Molecular Biology of the Cell
Yeast Irc6p is a novel type of conserved clathrin coat accessory protein that functions in clathrin-mediated traffic between the trans-Golgi network and endosomes, linking clathrin adaptor complex AP-1 and the Rab GTPase Ypt31p. Irc6p and the mammali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f943e7d499f8ab9ef86ef821ff211bc6
https://doi.org/10.1091/mbc.e12-07-0507
https://doi.org/10.1091/mbc.e12-07-0507
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 64:840-846
The complex of RuvBL1 and its homologue RuvBL2, two evolutionarily highly conserved eukaryotic proteins belonging to the AAA(+) (ATPase associated with diverse cellular activities) family of ATPases, was co-expressed in Escherichia coli. For crystall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d248d9913a3e362f6b5d7964f0e333f
https://doi.org/10.1107/s174430910802558x
https://doi.org/10.1107/s174430910802558x
Publikováno v:
Journal of Biological Chemistry. 281:38918-38929
RuvBL1 is an evolutionarily highly conserved eukaryotic protein belonging to the AAA(+)-family of ATPases (ATPase associated with diverse cellular activities). It plays important roles in essential signaling pathways such as the c-Myc and Wnt pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1269e709a4d38575bbc50f34a7b5dfd
https://doi.org/10.1074/jbc.m605625200
https://doi.org/10.1074/jbc.m605625200
Autor:
M. A. A. Thomaz, Ricardo Coelho, Martina Huber, Maria Arménia Carrondo, Bernard Haendler, Sabine Gorynia, Peter Donner, Gonçalo Lopes, Susana Goncalves, Pedro M. Matias
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 62:61-66
Human RuvB-like protein RuvBL1 plays important roles in essential signaling pathways like c-Myc and Wnt, in transcription, and in DNA repair and apoptosis. Crystals of both native and a Se-Met derivative were obtained and characterized. SAD data lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec922415407ca0a7376fdf935c33be05
https://doi.org/10.1107/s1744309105041400
https://doi.org/10.1107/s1744309105041400
Autor:
Peter Donner, Colin E. McVey, Pedro M. Matias, Sabine Gorynia, Filipa G. Pinho, Tiago M. Bandeiras, Maria Arménia Carrondo
Publikováno v:
Macromolecular Crystallography ISBN: 9789400725294
RuvBL1 and its homolog RuvBL2 belong to the AAA+ family of ATPases and play important roles in chromatin remodeling, in transcriptional regulation, in DNA repair and in the c-Myc and Wnt signaling pathways. Proteins involved in these pathways are oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::564a14fcc6f4f3b673f3067aa8333769
https://doi.org/10.1007/978-94-007-2530-0_5
https://doi.org/10.1007/978-94-007-2530-0_5
Autor:
Maria Arménia Carrondo, Peter Donner, Adam Round, Tiago M. Bandeiras, Dmitri I. Svergun, Sabine Gorynia, Filipa G. Pinho, Colin E. McVey, Pedro M. Matias, Clemens Vonrhein
Publikováno v:
Journal of structural biology. 176(3)
RuvBL1 (RuvB-like 1) and its homolog RuvBL2 are evolutionarily highly conserved AAA + ATPases essential for many cellular activities. They play an important role in chromatin remodeling, transcriptional regu- lation and DNA damage repair. RuvBL1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9403d2596732da5c2ce5f31b5e01f6b1
https://pubmed.ncbi.nlm.nih.gov/21933716
https://pubmed.ncbi.nlm.nih.gov/21933716
Autor:
Sabine Gorynia
Publikováno v:
Targeted Protein Database.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a86befa51ceaacfcc191e26b1208559
https://doi.org/10.2970/tpdb.2008.144
https://doi.org/10.2970/tpdb.2008.144
Autor:
Vincent Vuaroqueaux, Gerhard Kelter, Armin Maier, Sabine Gorynia, Thomas Metcalfe, Thomas Metz, Rebekka Krumbach, Heiner Fiebig, Jianing Guo, Andreas Ackermann
Publikováno v:
Cancer Research. 73:3835-3835
For compounds directed against molecular targets expressed in tumor cells, the ex vivo 3D tumor clonogenic assay (TCA) is a rapid and reliable ex vivo assay with a high predictive value for in vivo tumor sensitivity. Single cell suspensions prepared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5676cdcb51bf20ea963843b04b1ee43
https://doi.org/10.1158/1538-7445.am2013-3835
https://doi.org/10.1158/1538-7445.am2013-3835