Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Sabine Gogolok"'
1
Akademický článek
Reprogramming of Fibroblasts to Oligodendrocyte Progenitor-like Cells Using CRISPR/Cas9-Based Synthetic Transcription Factors
Autor: Mantas Matjusaitis, Laura J. Wagstaff, Andrea Martella, Bart Baranowski, Carla Blin, Sabine Gogolok, Anna Williams, Steven M. Pollard
Publikováno v: Stem Cell Reports, Vol 13, Iss 6, Pp 1053-1067 (2019)
Summary: Cell lineage reprogramming via transgene overexpression of key master regulatory transcription factors has been well documented. However, the poor efficiency and lack of fidelity of this approach is problematic. Synthetic transcription facto
Externí odkaz: https://doaj.org/article/edd7f09b05334865b6af465955dabac8
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2
Akademický článek
Distinct SoxB1 networks are required for naïve and primed pluripotency
Autor: Andrea Corsinotti, Frederick CK Wong, Tülin Tatar, Iwona Szczerbinska, Florian Halbritter, Douglas Colby, Sabine Gogolok, Raphaël Pantier, Kirsten Liggat, Elham S Mirfazeli, Elisa Hall-Ponsele, Nicholas P Mullin, Valerie Wilson, Ian Chambers
Publikováno v: eLife, Vol 6 (2017)
Deletion of Sox2 from mouse embryonic stem cells (ESCs) causes trophectodermal differentiation. While this can be prevented by enforced expression of the related SOXB1 proteins, SOX1 or SOX3, the roles of SOXB1 proteins in epiblast stem cell (EpiSC)
Externí odkaz: https://doaj.org/article/383310e3d27d44c8aad4b1b095ff1014
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3
Akademický článek
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Autor: Davide Danovi, Amos Folarin, Sabine Gogolok, Christine Ender, Ahmed M O Elbatsh, Pär G Engström, Stefan H Stricker, Sladjana Gagrica, Ana Georgian, Ding Yu, Kin Pong U, Kevin J Harvey, Patrizia Ferretti, Patrick J Paddison, Jane E Preston, N Joan Abbott, Paul Bertone, Austin Smith, Steven M Pollard
Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77053 (2013)
Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare resp
Externí odkaz: https://doaj.org/article/19166962924b408289d08b363d1c7682
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