Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sabine Glöckner"'
Publikováno v:
Laboratory Investigation. 82:1419-1426
Intratumoral heterogeneity mirrors subclonal diversity and might affect treatment response. To investigate molecular heterogeneity of primary breast cancer specimens, we determined the amplification status of growth regulatory genes (c-erbB2, topoiso
Publikováno v:
Hepatology. 35:110-116
It has recently been shown that epithelial cells derived from stem cells originating outside the liver are integrated into liver allografts. Whether epithelial intragraft chimerism protects transplants from rejection or chronic transplant dysfunction
Autor:
Florian Länger, Sabine Glöckner, Wolfram Kleeberger, Nadine Wilke, Ulrich Lehmann, Hans Kreipe
Publikováno v:
Laboratory Investigation. 81:565-571
Ductal carcinoma in situ (DCIS), as an identifiable progenitor lesion of invasive breast cancer, represents a morphologically, biologically, and prognostically heterogeneous disease. It is not clear which molecular mechanisms are involved in progress
Publikováno v:
Pathobiology. 68:196-201
The detection of donor-derived cells in the blood and tissues of graft recipients after solid organ transplantation is a readily observed phenomenon called microchimerism. Yet very little is known about the persistence and integration of recipient-de
Autor:
Sabine Glöckner, Ulrich Lehmann, Nadine Wilke, Florian Länger, Wolfram Kleeberger, Hans Kreipe
Publikováno v:
Pathobiology. 68:173-179
Gene amplification is one essential mechanism leading to oncogene activation which is supposed to play a major role in the pathogenesis of invasive breast cancer. However, using standard methodologies the detection of gene amplifications has been lim
Autor:
Hans Kreipe, Sabine Glöckner, Wolfram Kleeberger, Ulrich Lehmann, Anne Versmold, T. Rothämel, Martin Bredt, Axel Haverich
Publikováno v:
The American journal of pathology. 162(5)
Chimerism on the parenchymal level has been shown for several human allografts, including liver, heart, and kidney, with the integrated recipient-derived cells most likely originating from multipotent bone marrow precursors. We investigated whether c
Autor:
Britta Hasemeier, Sabine Glöckner, Ulrich Lehmann, Hans Kreipe, Florian Länger, Henning Feist
Publikováno v:
The American journal of pathology. 160(2)
The aberrant methylation of cytosine residues in the promoter region of growth regulatory genes is now widely recognized as an additional mechanism for gene inactivation in cancer cells. In this study we analyzed the methylation status of four growth
Autor:
Wolfram, Kleeberger, Thomas, Rothämel, Sabine, Glöckner, Peer, Flemming, Ulrich, Lehmann, Hans, Kreipe
Publikováno v:
Hepatology (Baltimore, Md.). 35(1)
It has recently been shown that epithelial cells derived from stem cells originating outside the liver are integrated into liver allografts. Whether epithelial intragraft chimerism protects transplants from rejection or chronic transplant dysfunction
Publikováno v:
Pathobiology : journal of immunopathology, molecular and cellular biology. 68(4-5)
Laser microdissection enables the contamination-free isolation of morphologically defined pure cell populations from archival formalin-fixed paraffin-embedded tissue specimens. Cells isolated by this method have been characterized by a wide variety o
Publikováno v:
Breast Cancer Research : BCR