Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sabine Gärtner"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303059 (2024)
Non-human primate (NHP)-based model systems are highly relevant for biomedical research. However, only few NHP cell lines are available and the generation of additional cell lines is an urgent need to help in the refinement and replacement of these m
Externí odkaz:
https://doaj.org/article/dac4eab56a984a2b89e19164147fae98
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0284048 (2023)
Non-human primate (NHP)-based model systems faithfully reproduce various viral diseases including Ebola, influenza, AIDS and Zika. However, only a small number of NHP cell lines are available and generation of additional cell lines could help to refi
Externí odkaz:
https://doaj.org/article/f47d62e5e8b149619ba9a5d5ef090804
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Influenza A virus (IAV) infection constitutes a significant health threat. Defective interfering particles (DIPs) can arise during IAV infection and inhibit spread of wild type (WT) IAV. DIPs harbor defective RNA segments, termed DI RNAs, th
Externí odkaz:
https://doaj.org/article/c7ccf226b7604915afa2db748893dad4
Autor:
Ruth Lydia Olga Lambertz, Ingo Gerhauser, Inga Nehlmeier, Sabine Gärtner, Michael Winkler, Sarah Rebecca Leist, Heike Kollmus, Stefan Pöhlmann, Klaus Schughart
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-7 (2020)
Abstract The host cell protease TMPRSS2 cleaves the influenza A virus (IAV) hemagglutinin (HA). Several reports have described resistance of Tmprss2 −/− knock-out (KO) mice to IAV infection but IAV of the H2 subtype have not been examined yet. He
Externí odkaz:
https://doaj.org/article/80ba7f63acba4da4966497bb19a13d35
Autor:
Heike Hofmann-Winkler, Abdul Rahman Siregar, Nesil Esiyok, Ignacio Rodríguez-Polo, Sabine Gärtner, Rüdiger Behr, Stefan Pöhlmann, Michael Winkler
Publikováno v:
Microorganisms, Vol 11, Iss 1, p 26 (2022)
Primate simplexviruses are closely related neurotropic herpesviruses, which are largely apathogenic in their respective host species. However, cross-species transmission of Macacine alphaherpesvirus 1 (McHV1, also termed herpes B virus) from rhesus m
Externí odkaz:
https://doaj.org/article/b006a65bba7746c3932cbe710d8ede8f
Autor:
Abdul Rahman Siregar, Sabine Gärtner, Jasper Götting, Philipp Stegen, Artur Kaul, Thomas F. Schulz, Stefan Pöhlmann, Michael Winkler
Publikováno v:
Viruses, Vol 14, Iss 1, p 91 (2022)
Primate simplex viruses, including Herpes simplex viruses 1 and 2, form a group of closely related herpesviruses, which establish latent infections in neurons of their respective host species. While neuropathogenic infections in their natural hosts a
Externí odkaz:
https://doaj.org/article/ad247bb36fd542399be7153f7e15d6d7
Autor:
Najat Bdeir, Prerna Arora, Sabine Gärtner, Markus Hoffmann, Udo Reichl, Stefan Pöhlmann, Michael Winkler
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212757 (2019)
Influenza A virus (IAV) infection poses a serious health threat and novel antiviral strategies are needed. Defective interfering particles (DIPs) can be generated in IAV infected cells due to errors of the viral polymerase and may suppress spread of
Externí odkaz:
https://doaj.org/article/7f2cbb2419ff40c4952fbd35f017afa7
Autor:
Michael Winkler, Sabine Gärtner, Lara Markus, Markus Hoffmann, Inga Nehlmeier, Michael Krawczak, Ulrike Sauermann, Stefan Pöhlmann
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224082 (2019)
The experimental infection of rhesus macaques (rh) with simian immunodeficiency virus (SIV) is an important model for human immunodeficiency virus (HIV) infection of humans. The interferon-induced transmembrane protein 3 (IFITM3) inhibits HIV and SIV
Externí odkaz:
https://doaj.org/article/cdad2039b2f240dba8c830ec091e0f8a
Autor:
Michael Winkler, Sabine Gärtner, Florian Wrensch, Michael Krawczak, Ulrike Sauermann, Stefan Pöhlmann
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172847 (2017)
Interferon-induced transmembrane proteins (IFITMs) have been recognized as important antiviral effectors of the innate immune system, both in cell culture and in infected humans. In particular, polymorphisms of the human IFITM3 gene have been shown t
Externí odkaz:
https://doaj.org/article/1ce59ba4dfac44a79ea8401d3fa908c2
Autor:
Ekaterina Chukhno, Sabine Gärtner, Abdul Rahman Siregar, Alexander Mehr, Marie Wende, Stoyan Petkov, Jasper Götting, Akshay Dhingra, Thomas Schulz, Stefan Pöhlmann, Michael Winkler
Publikováno v:
Viruses, Vol 11, Iss 11, p 1026 (2019)
The transmission of Macacine alphaherpesvirus 1 (McHV-1) from macaques, the natural host, to humans causes encephalitis. In contrast, human infection with Cercopithecine alphaherpesvirus 2 (CeHV-2), a closely related alphaherpesvirus from African ver
Externí odkaz:
https://doaj.org/article/ae4b722aec9b43e1a7303f02c80f85e3