Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sabine Fischer-Burkart"'
Publikováno v:
Microbial Cell, Vol 7, Iss 3, Pp 80-92 (2020)
Maintaining the identity of chromatin states requires mechanisms that ensure their structural integrity through the concerted actions of histone modifiers, readers, and erasers. Histone H3K9me and H3K27me are hallmarks of repressed heterochromatin, w
Externí odkaz:
https://doaj.org/article/a1043ddff8704ecbb1f2e12639c1eaed
Autor:
Magdalena Stock, Steffen Ullrich, Tilman E. Klassert, Christian Kosan, Ralf Küppers, Sabine Fischer-Burkart, Hortense Slevogt, Berit Jungnickel, Karsten Schärich, Samantha Frankenberger, Gianna Hirth, Daniel Kritsch, Lothar J. Strobl, Ursula Zimber-Strobl, Katrin Böttcher, Janine Sorgatz, Kerstin Braunschmidt
Publikováno v:
Molecular Immunology. 138:128-136
p53 plays a major role in genome maintenance. In addition to multiple p53 functions in the control of DNA repair, a regulation of DNA damage bypass via translesion synthesis has been implied in vitro. Somatic hypermutation of immunoglobulin genes for
Autor:
Sabine Fischer-Burkart, Yoshiyuki Hirano, Yasuha Kinugasa, Matías Capella, Nikolay Dobrev, Tamás Fischer, Ramón R. Barrales, Irmgard Sinning, Sigurd Braun, van Emden T, Lucía Martín Caballero, Yasushi Hiraoka
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (9), pp.910-921. ⟨10.1038/s41594-022-00831-6⟩
Nature Structural and Molecular Biology, 2022, 29 (9), pp.910-921. ⟨10.1038/s41594-022-00831-6⟩
Transcriptionally silent chromatin often localizes to the nuclear periphery. However, whether the nuclear envelope (NE) is a site for post-transcriptional gene repression is not well understood. Here we demonstrate that Schizosaccharomyces pombe Lem2
Publikováno v:
Microbial Cell
Microbial Cell, Vol 7, Iss 3, Pp 80-92 (2020)
Microbial Cell, Vol 7, Iss 3, Pp 80-92 (2020)
Maintaining the identity of chromatin states requires mechanisms that ensure their structural integrity through the concerted actions of histone modifiers, readers, and erasers. Histone H3K9me and H3K27me are hallmarks of repressed heterochromatin, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc7598ee651802a0007d67fcef4ae30
Autor:
Ignasi Forné, Cornelia Broenner, Axel Imhof, Lucía Martín Caballero, Mario Halic, Thomas S van Emden, Marta Forn, Zsuzsa Sarkadi, Marco Simonetta, Matías Capella, Sabine Fischer-Burkart, David P. Toczyski, Sigurd Braun
Telomeres and the shelterin complex cap and protect the ends of chromosomes. Telomeres are flanked by the subtelomeric sequences that have also been implicated in telomere regulation, although their role is not well defined. Here we show that, in Sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b8b0ad955adba5dbe9d9a3342b7cab
Autor:
Kathrin Davari, Ursula Zimber-Strobl, Nils-Sebastian Tomi, Berit Jungnickel, Katrin Böttcher, Sabine Fischer-Burkart, Samantha Frankenberger
Publikováno v:
Nucleic Acids Research
Nucleic Acids Res. 42, 3666-3674 (2014)
Nucleic Acids Res. 42, 3666-3674 (2014)
Immunoglobulin (Ig) diversification by somatic hypermutation in germinal center B cells is instrumental for maturation of the humoral immune response, but also bears the risk of excessive or aberrant genetic changes. Thus, introduction of DNA damage
Publikováno v:
Nucleic Acids Res. 38, 4701-4707 (2010)
Nucleic Acids Research
Nucleic Acids Research
In contrast to lower eukaryotes, most vertebrate cells are characterized by a moderate efficiency of homologous recombination (HR) and limited feasibility of targeted genetic modifications. As a notable exception, the chicken DT40 B cell line is dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a067c1a05fd3eb4468513d2ec96c4e
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=4992
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=4992