Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sabine Duewel"'
Autor:
Sabrina Hoebenreich, Klaus Harms, Vasundara Srinivasan, Sabine Duewel, Luca Schmermund, Eric Meggers, Tabea Melanie Faber
Publikováno v:
ACS Catalysis. 10:1272-1277
By using structure-guided directed evolution, the substrate scope of the FeII and α-ketoglutarate dependent halogenase Wi-WelO15 from Westiella intricata HT-29-1 was engineered to enable chemo-, regio-, and diastereoselective chlorination of unactiv
Publikováno v:
ChemBioChem. 18:685-691
Every year numerous protein engineering and directed evolution studies are published, increasing the knowledge that could be used by protein engineers. Here we test a protein engineering strategy that allows quick access to improved biocatalysts with
Autor:
Kara E. Ranaghan, Gerrit E. Benary, Luca Schmermund, Adrian J. Mulholland, Sabrina Hoebenreich, Sabine Duewel, Nathalie Nett, Diederik J. Opperman
Publikováno v:
Molecular Catalysis. 502:111404
We report an engineered panel of ene-reductases (ERs) from Thermus scotoductus SA-01 (TsER) that combines control over facial selectivity in the reduction of electron deficient C C double bonds with thermostability (up to 70 °C), organic solvent tol