Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sabine Drechsler"'
Autor:
R. Ehret, A. Kob, Enrico Sabbioni, Sabine Drechsler, Pascal Colpo, E. Thedinga, Francesca Broggi, Laura Ceriotti, François Rossi, Jessica Ponti
Publikováno v:
Sensors and Actuators B: Chemical. 123:769-778
In this work cell adhesion and cellular response to metal compounds classified as cytotoxic and carcinogenic are assessed by electrical impedance measurement in a 96-well plate prototype. This system integrates at the bottom of each well interdigitat
Autor:
Ralf Ehret, Mirko Lehmann, Ricarda Niendorf, Ingo Freund, Sabine Drechsler, Heiko Holst, Elke Thedinga, Andreas Keuer, Axel Kob, Werner Baumann
Publikováno v:
Toxicology and Applied Pharmacology. 220:33-44
To characterize modes of action of substances and their cytotoxic effects Bionas GmbH has developed a new screening system to allow the continuous recording of how an active substance can act (Bionas® 2500 analyzing system). In the pharmaceutical in
Publikováno v:
Proceedings SENSOR 2011.
Autor:
Sabine Drechsler, Jörg Andrä
Publikováno v:
Journal of bioenergetics and biomembranes. 43(3)
Antimicrobial peptides are promising anti-cancer agents with a unique mode of action. We established the usage of a chip-based sensor to monitor the dynamic interplay between cells on the chip and peptides and compared it with endpoint tests. Human n
Autor:
R. Ehret, A. Kob, E. Thedinga, Jessica Ponti, Laura Ceriotti, François Rossi, Sabine Drechsler, Pascal Colpo
Publikováno v:
Analytical biochemistry. 371(1)
A multiparametric chip-based system was employed to measure cell adhesion, metabolism, and response to metal compounds previously classified as cytotoxic in immortalized mouse fibroblasts (BALB/3T3 cell line). The system measures in parallel, online,
Autor:
Anett Ullrich, Mirko Lehmann, Andreas Keuer, Axel Kob, Dieter Runge, Ricarda Niendorf, Sabine Drechsler, Elke Thedinga, Ralf Ehret, Ingo Freund
Publikováno v:
ALTEX. 24(1)
Prediction of liver toxicity and compound responses continues to be a major challenge for the pharmaceutical industry. In vitro studies on liver cells have been developed to reduce or replace animal experiments. However, most of the tests in use are
Autor:
Stephan Ladenburger, Wolfgang H. Fischer, Sabine Drechsler, Harald Gschaidmeier, Lothar Faerber
Publikováno v:
European journal of pharmacology. 560(1)
The 5-HT3 receptor is a pentameric ligand-gated cation channel which is found in the central and peripheral nervous system and on extraneuronal locations like lymphocytes, monocytes and fetal tissue. Five monomer subtypes, the 5-HT(3A-E) subunits, ha
Autor:
Hans Meffert, Enno Christophers, Gottfried Weidinger, Lothar Faerber, Gustav Mahrle, Sabine Drechsler, Matthias Braeutigam, Ulrich Mrowietz, H. J. Schulze
Publikováno v:
American journal of clinical dermatology. 2(1)
A meta-analysis of 3 major German studies conducted between 1989 and 1994 with cyclosporine in severe psoriasis was performed to allow an integrated evaluation of the efficacy and tolerability of cyclosporine in this indication.All 3 studies were pro
Publikováno v:
Toxicology Letters. 189:S87-S88
Autor:
Gerhard Gaedicke, Günther Henze, Rudolf Erttmann, Peter Grass, W. Hartmann, Lothar Faerber, Klaus Kutz, Sabine Drechsler
Publikováno v:
Pediatric hematology and oncology. 13(5)
A pharmacokinetic study in children was performed to assess whether the pharmacokinetic profile of tropisetron in pediatric patients in similar to that in adults. In three pediatric centers, three dosages were tested in two age groups during chemothe