Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sabine D. Steigerwald"'
Publikováno v:
Genes & Development. 4:1277-1287
The promoter region of the X-linked human phosphoglycerate kinase-1 (PGK-1) gene is a CpG island, similar to those often found near autosomal genes. We used ligation-mediated polymerase chain reaction (PCR) for a genomic sequencing study in which 450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53f0bdcc403cb6e42dafdde41de1fd7
https://doi.org/10.1101/gad.4.8.1277
https://doi.org/10.1101/gad.4.8.1277
Publikováno v:
Nucleic Acids Research. 18:1435-1439
DNA methylation at specific sites is most frequently studied by use of methylation-sensitive restriction endonucleases and Southern blotting. We report here that the sensitivity of this method can be increased several-hundred-fold by applying a ligat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2231d6518f0d81d5b3bdf6ebaa40791c
https://doi.org/10.1093/nar/18.6.1435
https://doi.org/10.1093/nar/18.6.1435
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(21)
The 5' region of the gene encoding human X chromosome-linked phosphoglycerate kinase 1 (PGK1) is a promoter-containing CpG island known to be methylated at 119 of 121 CpG dinucleotides in a 450-base-pair region on the inactive human X chromosome in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d76c0bf944099a57254be148050521f
https://pubmed.ncbi.nlm.nih.gov/2236038
https://pubmed.ncbi.nlm.nih.gov/2236038
Autor:
Gerd P. Pfeifer, Sabine D. Steigerwald
Publikováno v:
Experimental Cell Research. 178:41-50
The DNA 5-methylcytosine content has been analyzed in the human melanoma cell line M21 at several time points after induction of differentiation by a variety of inducers. 5-Aza-2′-deoxycytidine reduces DNA methylation to about 50% of the control le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ae4d93d836b66cd344fcef1d1c52c8
https://doi.org/10.1016/0014-4827(88)90376-x
https://doi.org/10.1016/0014-4827(88)90376-x
Publikováno v:
Cancer Letters. 39:185-192
We have studied the overall 5-methylcytosine content and the percentage of methylated CpG-dinucleotides in 25 cases of untreated human acute leukemias. For comparison, normal leucocyte subpopulations were similarly analyzed. The methylation levels in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0152ad0ab90d45cf251a3f17664aa86d
https://doi.org/10.1016/0304-3835(88)90103-6
https://doi.org/10.1016/0304-3835(88)90103-6
Publikováno v:
Science (New York, N.Y.). 246(4931)
Genomic sequencing permits studies of in vivo DNA methylation and protein-DNA interactions, but its use has been limited because of the complexity of the mammalian genome. A newly developed genomic sequencing procedure in which a ligation mediated po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81e9e45151afb3fd324c4d77f796727
https://pubmed.ncbi.nlm.nih.gov/2814502
https://pubmed.ncbi.nlm.nih.gov/2814502
Publikováno v:
Cell biophysics. 15(1-2)
The human melanoma cell line M21 can be induced to differentiate into oligodendrocyte-like cells with concommitant cessation of cell division. Cytosine-arabinoside, 5-aza-2'-deoxycytidine, hydroxyurea, aphidicolin, and phorbol-12-myristate-13-acetate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be0de5c5d9d5cd5ec6e5bb29973678b
https://pubmed.ncbi.nlm.nih.gov/2476229
https://pubmed.ncbi.nlm.nih.gov/2476229
Publikováno v:
Cell Biophysics; 1989, Vol. 15 Issue 1/2, p79-86, 8p