Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sabine D. Jordan"'
Autor:
Stephanie J Papp, Anne-Laure Huber, Sabine D Jordan, Anna Kriebs, Madelena Nguyen, James J Moresco, John R Yates III, Katja A Lamia
Publikováno v:
eLife, Vol 4 (2015)
The circadian transcriptional repressors cryptochrome 1 (Cry1) and 2 (Cry2) evolved from photolyases, bacterial light-activated DNA repair enzymes. In this study, we report that while they have lost DNA repair activity, Cry1/2 adapted to protect geno
Externí odkaz:
https://doaj.org/article/0a9aa928dda64b9dac1ff996dfe76662
Publikováno v:
Journal of Biological Rhythms. 34:401-409
Circadian clocks allow organisms to anticipate repetitive changes in their environment such as food availability, temperature, and predation. While they most clearly manifest at the behavioral level, driving sleep-wake cycles, for example, they also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a50e139a504f972fa359fcbcbefb26
https://doi.org/10.1177/0748730419858525
https://doi.org/10.1177/0748730419858525
Autor:
Carsten Merkwirth, Paola Martinelli, Anne Korwitz, Michela Morbin, Hella S Brönneke, Sabine D Jordan, Elena I Rugarli, Thomas Langer
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003021 (2012)
Fusion and fission of mitochondria maintain the functional integrity of mitochondria and protect against neurodegeneration, but how mitochondrial dysfunctions trigger neuronal loss remains ill-defined. Prohibitins form large ring complexes in the inn
Externí odkaz:
https://doaj.org/article/5db45e9d209245a78fd19f8f0e725ed6
Autor:
Stephanie J. Papp, Sabine D. Jordan, Zhizhong Li, Christian M. Metallo, Anne Laure Huber, Madelena Nguyen, Emma Henriksson, Katja A. Lamia, Anna Kriebs, Martina Wallace, Alanna B. Chan
Publikováno v:
Molecular Cell. 64:774-789
For many years, a connection between circadian clocks and cancer has been postulated. Here, we describe an unexpected function for the circadian repressor CRY2 as a component of an FBXL3-containing E3 ligase that recruits T58-phosphorylated c-MYC for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793864d3922e4910591997c1208cecc6
https://doi.org/10.1016/j.molcel.2016.10.012
https://doi.org/10.1016/j.molcel.2016.10.012
Autor:
Carsten Merkwirth, Jenni Durieux, Kristan K. Steffen, Sarah U. Tronnes, Johan Auwerx, Olli Matilainen, Evan G. Williams, Laurent Mouchiroud, Sabine D. Jordan, Suzanne Wolff, Virginia Murillo, Reuben J. Shaw, Andrew Dillin, Pedro M. Quirós, Virginija Jovaisaite
Publikováno v:
Cell, vol 165, iss 5
Across eukaryotic species, mild mitochondrial stress can have beneficial effects on the lifespan of organisms. Mitochondrial dysfunction activates an unfolded protein response (UPR(mt)), a stress signaling mechanism designed to ensure mitochondrial h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31c26dd40985123aa7a24bf87ba43e34
https://doi.org/10.1016/j.cell.2016.04.012
https://doi.org/10.1016/j.cell.2016.04.012
Autor:
Xuan Zhao, Ruth T. Yu, Colby R. Sandate, Anne Laure Huber, Stephanie J. Papp, Ronald M. Evans, Megan Vaughan, Emma Henriksson, Drew Duglan, Megan E. Afetian, Michael Downes, Erin Soto, Katja A. Lamia, Sabine D. Jordan, Anna Kriebs, Alanna B. Chan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 114(33)
Nuclear hormone receptors (NRs) regulate physiology by sensing lipophilic ligands and adapting cellular transcription appropriately. A growing understanding of the impact of circadian clocks on mammalian transcription has sparked interest in the inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac635a1332cbd2048a3ec5958951b42
https://pubmed.ncbi.nlm.nih.gov/28751364
https://pubmed.ncbi.nlm.nih.gov/28751364
Autor:
Anne Laure Huber, Drew Duglan, Katja A. Lamia, Anastasia Kralli, Megan E. Afetian, Megan Vaughan, Ronald M. Evans, Michael Downes, Weiwei Fan, Sabine D. Jordan, Stephanie J. Papp, Ruth T. Yu, Madelena Nguyen, Emma Henriksson, Anna Kriebs
Publikováno v:
Cell metabolism. 26(1)
Summary Cellular metabolite balance and mitochondrial function are under circadian control, but the pathways connecting the molecular clock to these functions are unclear. Peroxisome proliferator-activated receptor delta (PPARδ) enables preferential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f19b5546dc1e66e38a3e047c20c13d
https://pubmed.ncbi.nlm.nih.gov/28683290
https://pubmed.ncbi.nlm.nih.gov/28683290
Autor:
Xiaosong Ma, Pablo J. Enriori, C. Ronald Kahn, Chun Xu, Frances M. Ashcroft, Ruth Janoschek, Brigitte Hampel, Sabine D. Jordan, Eva Rother, Jens C. Brüning, A. Christine Könner, Gregory S. Barsh, Leona Plum, Michael A. Cowley
Publikováno v:
Monash University
SummaryInsulin action in the central nervous system regulates energy homeostasis and glucose metabolism. To define the insulin-responsive neurons that mediate these effects, we generated mice with selective inactivation of the insulin receptor (IR) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c016b567d398a14c57e03151665e6b38
https://ora.ox.ac.uk/objects/uuid:e136f6b4-8c92-4ff2-8937-40894dd5d76e
https://ora.ox.ac.uk/objects/uuid:e136f6b4-8c92-4ff2-8937-40894dd5d76e
Autor:
Anne Laure Huber, James J. Moresco, Madelena Nguyen, Stephanie J. Papp, Sabine D. Jordan, Anna Kriebs, Katja A. Lamia, John R. Yates
Publikováno v:
eLife, Vol 4 (2015)
eLife
eLife
The circadian transcriptional repressors cryptochrome 1 (Cry1) and 2 (Cry2) evolved from photolyases, bacterial light-activated DNA repair enzymes. In this study, we report that while they have lost DNA repair activity, Cry1/2 adapted to protect geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d942688618bde3300008990a7d84731
https://elifesciences.org/articles/04883
https://elifesciences.org/articles/04883