Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sabine C. Fischer"'
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108106- (2023)
Summary: Embryos develop in a concerted sequence of spatiotemporal arrangements of cells. In the preimplantation mouse embryo, the distribution of the cells in the inner cell mass evolves from a salt-and-pepper pattern to spatial segregation of two d
Externí odkaz:
https://doaj.org/article/4e6d628a679d46d4b62e3ace3718c178
Cell fate clusters in ICM organoids arise from cell fate heredity and division: a modelling approach
Autor:
Tim Liebisch, Armin Drusko, Biena Mathew, Ernst H. K. Stelzer, Sabine C. Fischer, Franziska Matthäus
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract During the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first decision, the trophectoderm and the inner cell mass are formed. Subsequently, the inner cell mass segregates into the epiblast and
Externí odkaz:
https://doaj.org/article/bc322e20319b4056bfa3b840aeedbfc9
Autor:
Kerstin Schmid, Andreas Knote, Alexander Mück, Keram Pfeiffer, Sebastian von Mammen, Sabine C. Fischer
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2022)
In interdisciplinary fields such as systems biology, good communication between experimentalists and theorists is crucial for the success of a project. Theoretical modeling in physiology usually describes complex systems with many interdependencies.
Externí odkaz:
https://doaj.org/article/5d68d7ecb5744cefbe02fef45c144b1d
Autor:
Wagner Steuer Costa, Petrus Van der Auwera, Caspar Glock, Jana F. Liewald, Maximilian Bach, Christina Schüler, Sebastian Wabnig, Alexandra Oranth, Florentin Masurat, Henrik Bringmann, Liliane Schoofs, Ernst H. K. Stelzer, Sabine C. Fischer, Alexander Gottschalk
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The GABAergic and peptidergic neuron RIS mediates sleep in Caenorhabditis elegans. The authors demonstrated here that RIS also functions as a locomotion stop neuron. Its optogenetic stimulation caused acute and persistent inhibition of locomotion, an
Externí odkaz:
https://doaj.org/article/dadadbc0392146fd8d67f3ec1c6b32b4
Publikováno v:
Frontiers in Bioinformatics, Vol 1 (2022)
In interdisciplinary fields such as systems biology, close collaboration between experimentalists and theorists is crucial for the success of a project. Theoretical modeling in physiology usually describes complex systems with many interdependencies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ac45dd5584daf7548228991e22e809
https://doi.org/10.3389/fbinf.2021.774300
https://doi.org/10.3389/fbinf.2021.774300
Autor:
Ernst H. K. Stelzer, Roberto Covino, Anja Seybert, Robert K. Ernst, Michael Gecht, Harald F. Hofbauer, Sabine C. Fischer, Gerhard Hummer, Achilleas S. Frangakis
Publikováno v:
The Journal of Cell Biology
Phosphatidic acid (PA) lipids have a dual role as building blocks for membrane biogenesis and as active signaling molecules. This study establishes the molecular details of selective PA recognition by the transcriptional regulator Opi1 from baker’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b5981da270b63da409278f3bfbae74
https://doi.org/10.1083/jcb.201802027
https://doi.org/10.1083/jcb.201802027
Autor:
Sabine C. Fischer
Publikováno v:
Computational Biology ISBN: 9780994438195
Multicellular organisms are inherently three-dimensional. This leads to complex intercellular interactions that cannot be reproduced in two-dimensional cell culture. Instead, three-dimensional spheroids, ball-shaped cell aggregates, arise as model sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b03d677a0ced6b5bf36cccc4f60c3295
https://doi.org/10.15586/computationalbiology.2019.ch1
https://doi.org/10.15586/computationalbiology.2019.ch1
Autor:
Sebastian Wabnig, Petrus Van der Auwera, Jana F. Liewald, Alexandra Oranth, Maximilian Bach, Christina Schüler, Florentin Masurat, Alexander Gottschalk, Liliane Schoofs, Henrik Bringmann, Ernst H. K. Stelzer, Sabine C. Fischer, Wagner Steuer Costa, Caspar Glock
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Animals must slow or halt locomotion to integrate sensory inputs or to change direction. In Caenorhabditis elegans, the GABAergic and peptidergic neuron RIS mediates developmentally timed quiescence. Here, we show RIS functions additionally as a loco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87d78a102165a5f289fd5452edda008
https://doi.org/10.1038/s41467-019-12098-5
https://doi.org/10.1038/s41467-019-12098-5
Autor:
Franziska Matthäus, Ernst H. K. Stelzer, Biena Mathew, Tim Liebisch, Armin Drusko, Sabine C. Fischer
During the mammalian preimplantation phase, cells undergo two subsequent cell fate decisions. During the first cell fate decision, cells become either part of an outer trophectoderm or part of the inner cell mass. Subsequently, the inner cell mass (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ddf4a445df0a5fcb146f87fef7f964
Autor:
Christian Schröter, Biena Mathew, Ernst H. K. Stelzer, Silvia Muñoz-Descalzo, Elena Corujo-Simon, Sabine C. Fischer
Publikováno v:
Biophysical Journal
During mammalian preimplantation, cells of the inner cell mass (ICM) adopt either an embryonic or an extraembryonic fate. This process is tightly regulated in space and time and has been studied previously in mouse embryos and embryonic stem cell mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb99799758e7f7075bb49ca036aef494
https://pubmed.ncbi.nlm.nih.gov/30514631
https://pubmed.ncbi.nlm.nih.gov/30514631