Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sabine Blouquit-Laye"'
MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology
Autor:
Florence Sonneville, Manon Ruffin, Christelle Coraux, Nathalie Rousselet, Philippe Le Rouzic, Sabine Blouquit-Laye, Harriet Corvol, Olivier Tabary
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Downregulation of the anoctamin 1 calcium channel in airway epithelial cells contributes to pathology in cystic fibrosis. Here the authors show that microRNA-9 targets anoctamin 1 and that inhibiting this interaction improves mucus dynamics in mouse
Externí odkaz:
https://doaj.org/article/ebe9c1b9abb94fe688798f585d120b14
Autor:
Vincent Rincheval, Mickael Lelek, Elyanne Gault, Camille Bouillier, Delphine Sitterlin, Sabine Blouquit-Laye, Marie Galloux, Christophe Zimmer, Jean-François Eleouet, Marie-Anne Rameix-Welti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Respiratory syncytial virus (RSV) induces formation of inclusion bodies (IBs) sheltering viral RNA synthesis. Here, Rincheval et al. identify highly dynamic IB-associated granules (IBAGs) that accumulate newly synthetized viral mRNA and the viral M2-
Externí odkaz:
https://doaj.org/article/df479c97011247a08f1d1f4bd3054dfc
Autor:
Anastasia Tchoukaev, Jessica Taytard, Nathalie Rousselet, Carine Rebeyrol, Dominique Debray, Sabine Blouquit-Laye, Marie-Pierre Moisan, Aline Foury, Loic Guillot, Harriet Corvol, Olivier Tabary, Philippe Le Rouzic
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cystic fibrosis (CF) is characterized by a chronic pulmonary inflammation. In CF, glucocorticoids (GC) are widely used, but their efficacy and benefit/risk ratio are still debated. In plasma, corticosteroid-binding globulin (CBG) binds 90% of GC and
Externí odkaz:
https://doaj.org/article/91e1ba35d81f4529b9baa0146696bcf0
Wnt/β-catenin signaling modulates human airway sensitization induced by β2-adrenoceptor stimulation.
Autor:
Christophe Faisy, Stanislas Grassin-Delyle, Sabine Blouquit-Laye, Marion Brollo, Emmanuel Naline, Alain Chapelier, Philippe Devillier
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111350 (2014)
BACKGROUND: Regular use of β2-agonists may enhance non-specific airway responsiveness. The wingless/integrated (Wnt) signaling pathways are responsible for several cellular processes, including airway inflammation and remodeling while cAMP-PKA casca
Externí odkaz:
https://doaj.org/article/7e8b4ed647364af592d96b498fbd5815
Autor:
Vincent Le Moigne, Sabine Blouquit-Laye, Aurore Desquesnes, Fabienne Girard-Misguich, Jean-Louis Herrmann
Publikováno v:
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2022, ⟨10.1093/jac/dkac348⟩
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2022, ⟨10.1093/jac/dkac348⟩
Background Mycobacterium abscessus (Mabs), a rapidly growing Mycobacterium species, is considered an MDR organism. Among the standard antimicrobial multi-drug regimens against Mabs, amikacin is considered as one of the most effective. Parenteral amik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d5bf69b69d6072ccd0f1b18c0fea58
https://doi.org/10.1093/jac/dkac348
https://doi.org/10.1093/jac/dkac348
Autor:
Pauline, Bardin, Emmeline, Marchal-Duval, Florence, Sonneville, Sabine, Blouquit-Laye, Nathalie, Rousselet, Philippe, Le Rouzic, Harriet, Corvol, Olivier, Tabary
Publikováno v:
The Journal of pathology and bacteriology
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 245 (4), pp.410-420. ⟨10.1002/path.5095⟩
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 245 (4), pp.410-420. ⟨10.1002/path.5095⟩
International audience; Cystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thickened mucus, which impair m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f906c6f3a0ccd6cf360edc36c538067d
https://www.hal.inserm.fr/inserm-02390385
https://www.hal.inserm.fr/inserm-02390385
Autor:
Nathalie Rousselet, Pauline Bardin, Sabine Blouquit-Laye, Philippe Le Rouzic, Harriet Corvol, Emmeline Marchal-Duval, Olivier Tabary, Florence Sonneville
Publikováno v:
The Journal of pathology and bacteriology
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 245 (4), pp.410-420. ⟨10.1002/path.5095⟩
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 245 (4), pp.410-420. ⟨10.1002/path.5095⟩
International audience; Cystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thickened mucus, which impair m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3936fe897630b448a6909972119762a9
https://www.hal.inserm.fr/inserm-02390385
https://www.hal.inserm.fr/inserm-02390385
MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology
Autor:
Olivier Tabary, Nathalie Rousselet, Philippe Le Rouzic, Florence Sonneville, Harriet Corvol, Sabine Blouquit-Laye, Manon Ruffin, Christelle Coraux
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.3231-3243. ⟨10.1038/s41467-017-00813-z⟩
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, 2017, 8 (1), pp.3231-3243. ⟨10.1038/s41467-017-00813-z⟩
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.3231-3243. ⟨10.1038/s41467-017-00813-z⟩
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, 2017, 8 (1), pp.3231-3243. ⟨10.1038/s41467-017-00813-z⟩
Cystic fibrosis results from reduced cystic fibrosis transmembrane conductance regulator protein activity leading to defective epithelial ion transport. Ca2+-activated Cl− channels mediate physiological functions independently of cystic fibrosis tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a60b25286dc2a3d479b009f6f0a314
https://www.hal.inserm.fr/inserm-01614066
https://www.hal.inserm.fr/inserm-01614066
Autor:
Elise Blanchard, Annick Clement, Mélanie Voland, Sabine Blouquit-Laye, Loïc Guillot, Philippe Puyo, Olivier Tabary, Solenne Marie, Monique Bonora, Emmanuel Naline, Manon Ruffin, Philippe Le Rouzic, Harriet Corvol
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1832:2340-2351
Cystic fibrosis (CF) airway epithelium is constantly subjected to injury events due to chronic infection and inflammation. Moreover, abnormalities in CF airway epithelium repair have been described and contribute to the lung function decline seen in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33326612c7a15f9329e205c3042745e3
https://doi.org/10.1016/j.bbadis.2013.09.012
https://doi.org/10.1016/j.bbadis.2013.09.012
Autor:
Emmanuel Naline, Louis-Jean Couderc, Marc Fischler, Amparo Buenestado, Morgan Le Guen, Christophe Faisy, Stanislas Grassin-Delyle, Philippe Devillier, Sabine Blouquit-Laye
Publikováno v:
Pharmacology & Therapeutics. 134:366-379
Intranasal administration is a non-invasive route for drug delivery, which is widely used for the local treatment of rhinitis or nasal polyposis. Since drugs can be absorbed into the systemic circulation through the nasal mucosa, this route may also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20bcd0ec059a8c88e890c497b827f0f3
https://doi.org/10.1016/j.pharmthera.2012.03.003
https://doi.org/10.1016/j.pharmthera.2012.03.003