Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sabine Baxter"'
Autor:
Vanessa Pirrone, Shendra R. Miller, Simon Cocklin, Sabine Baxter, Ferit Tuzer, Irwin Chaiken, Judith M. LaLonde, M. Umashankara, Jeffrey C. Klein, Navneet Jawanda, Fred C. Krebs, Arne Schön, Amos B. Smith, Joseph Sodroski, Ernesto Freire, Navid Madani, Hosahudya N. Gopi, Isaac Zentner
Publikováno v:
Journal of Medicinal Chemistry. 51:2638-2647
Structure-activity correlations were investigated for substituted peptide conjugates that function as dual receptor site antagonists of HIV-1 gp120. A series of peptide conjugates were constructed via click reaction of both aryl and alkyl acetylenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3bd9ceed55edf3bccdc7ccc21887b3
https://doi.org/10.1021/jm070814r
https://doi.org/10.1021/jm070814r
Autor:
Irwin Chaiken, Nicoleta J. Economou, Mark Contarino, Sabine Baxter, Monika Jost, Karyn McFadden, Patrick J. Loll, Gianfranco Pasut, Adrian E. Harrington, Meirav Zaks-Zilberman, Tetsuya Ishino, Sam Lievens, Jan Tavernier
Publikováno v:
Biochemistry. 50(35)
Human interleukin-5 receptor alpha (IL5R alpha) is a glycoprotein that contains four N-glycosylation sites in the extracellular region. Previously, we found that enzymatic deglycosylation of IL5R alpha resulted in complete loss of IL5 binding To loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129316d7bb080b970ed1cf754acd1bc1
https://pubmed.ncbi.nlm.nih.gov/21770429
https://pubmed.ncbi.nlm.nih.gov/21770429
Autor:
Shibani Bhattacharya, David J.E. Callaway, Sabine Baxter, David Cowburn, Zhongping Dai, Jianquan Li, Zimei Bu
Publikováno v:
The Journal of biological chemistry. 285(13)
The mammalian Na(+)/H(+) exchange regulatory factor 1 (NHERF1) is a multidomain scaffolding protein essential for regulating the intracellular trafficking and macromolecular assembly of transmembrane ion channels and receptors. NHERF1 consists of tan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b30c9ec7f7911b6ecaac143b0196e7
https://pubmed.ncbi.nlm.nih.gov/20042604
https://pubmed.ncbi.nlm.nih.gov/20042604
Autor:
Vanessa Pirrone, Sandya Ajith, Karyn McFadden, Sabine Baxter, Hosahudya N. Gopi, Simon Cocklin, Fred C. Krebs, Irwin Chaiken, Isaac Zentner, Ferit Tuzer, Navneet Jawanda
Publikováno v:
Journal of molecular recognition : JMR. 22(2)
In this work, we identified a high affinity and potency metallocene-containing triazole peptide conjugate that suppresses the interactions of HIV-1 envelope gp120 at both its CD4 and co-receptor binding sites. The ferrocene-peptide conjugate, HNG-156
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df1749d5d801312bef18e02a7ae591a
https://pubmed.ncbi.nlm.nih.gov/18498083
https://pubmed.ncbi.nlm.nih.gov/18498083
Autor:
Sabine Baxter, Naheed Mahmood, Irwin Chaiken, Karyn McFadden, Robin J. Shattock, Simon Cocklin, Hosahudya N. Gopi, Sandya Ajith
Publikováno v:
Proteins. 67(3)
The first, critical stage of HIV-1 infection is fusion of viral and host cellular mem- branes initiated by a viral envelope glycoprotein gp120. We evaluated the potential to form a chimeric protein entry inhibitor that combines the action of two gp12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d1645ec79a1b9bbd802a0ac2b30cb8
https://pubmed.ncbi.nlm.nih.gov/17348010
https://pubmed.ncbi.nlm.nih.gov/17348010
Autor:
Syna A. Kuriakose, Julio Martín-García, Simon Cocklin, Manideepthi Nimmagadda, Sandya Ajith, Sabine Baxter, James Arthos, Bianca Querido, Irwin Chaiken, Hosahudya N. Gopi, Claudia Cicala
The AIDS epidemic continues to spread at an alarming rate worldwide, especially in developing countries. One approach to solving this problem is the generation of anti-human immunodeficiency virus (HIV) compounds with inhibition spectra broad enough
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af80f34531a4d05d7f95d68d01eb05be
https://europepmc.org/articles/PMC1866025/
https://europepmc.org/articles/PMC1866025/
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7062412e27401f15ed3e0ab5140fbdfc
https://doi.org/10.1096/fasebj.20.4.a465-c
https://doi.org/10.1096/fasebj.20.4.a465-c
Publikováno v:
Biotechnology and Applied Biochemistry. 45:167
Here, we demonstrate for the first time that the hollow-fibre bioreactor is an excellent tool for the production of Drosophila-expressed recombinant proteins. Using the example of the soluble extracellular portion of the human IL-5 (interleukin 5) re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4504e2d26328083da2517eb688313801
https://doi.org/10.1042/ba20060074
https://doi.org/10.1042/ba20060074
Autor:
Hosahudya Gopi, M. Umashankara, Vanessa Pirrone, Judith LaLonde, Navid Madani, Ferit Tuzer, Sabine Baxter, Isaac Zentner, Simon Cocklin, Navneet Jawanda, Shendra R. Miller, Arne Schön, Jeffrey C. Klein, Ernesto Freire, Fred C. Krebs, Amos B. Smith, Joseph Sodroski, Irwin Chaiken
Publikováno v:
Journal of Medicinal Chemistry; Apr2008, Vol. 51 Issue 9, p2638-2647, 10p