Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Sabine Bailly"'
Autor:
Mohammad Al Tarrass, Lucid Belmudes, Dzenis Koça, Valentin Azemard, Hequn Liu, Tala Al Tabosh, Delphine Ciais, Agnès Desroches-Castan, Christophe Battail, Yohann Couté, Claire Bouvard, Sabine Bailly
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background BMP9 and BMP10 are two major regulators of vascular homeostasis. These two ligands bind with high affinity to the endothelial type I kinase receptor ALK1, together with a type II receptor, leading to the direct phosphorylation of
Externí odkaz:
https://doaj.org/article/5764a562c7064ed688fbad16999dd25c
Autor:
Martina Rossi, Aude Salomon, Nicolas Chaumontel, Jenny Molet, Sabine Bailly, Emmanuelle Tillet, Claire Bouvard
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The Cre-lox system is a versatile and powerful tool used in mouse genetics. It allows spatial and/or temporal control of the deletion of a target gene. The Rosa26-CreERT2 (R26CreERT2) mouse model allows ubiquitous expression of CreERT2. Once
Externí odkaz:
https://doaj.org/article/bb0c2b87d232476aaab591ac15c73dcf
Autor:
Roberto Rodrigues Ferreira, Elen Mello de Souza, Glaucia Vilar-Pereira, Wim M. S. Degrave, Rayane da Silva Abreu, Marcelo Meuser-Batista, Nilma Valéria Caldeira Ferreira, Steve Ledbeter, Robert H. Barker, Sabine Bailly, Jean-Jacques Feige, Joseli Lannes-Vieira, Tania C. de Araújo-Jorge, Mariana Caldas Waghabi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chronic Chagasic cardiomyopathy (CCC), a progressive inflammatory and fibrosing disease, is the most prominent clinical form of Chagas disease, a neglected tropical disease caused by Trypanosoma cruzi infection. During CCC, the parasite remains insid
Externí odkaz:
https://doaj.org/article/e96a0e4a824f40eaa385d90cfb0289da
Autor:
Roberto Rodrigues Ferreira, Mariana Caldas Waghabi, Sabine Bailly, Jean-Jacques Feige, Alejandro M. Hasslocher-Moreno, Roberto M. Saraiva, Tania C. Araujo-Jorge
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
The anti-inflammatory cytokine transforming growth factor beta (TGF-β) plays an important role in Chagas disease (CD), a potentially life-threatening illness caused by Trypanosoma cruzi. In this review we revisited clinical studies in CD patients co
Externí odkaz:
https://doaj.org/article/27bf50e618654d5294029898be764e54
Autor:
Mariana Caldas Waghabi, Roberto Rodrigues Ferreira, Rayane da Silva Abreu, Wim Degrave, Elen Mello de Souza, Sabine Bailly, Jean-Jacques Feige, Tania C de Araújo-Jorge
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 117 (2022)
Transforming growth factor beta (TGF-β) is deeply involved on the pathogenesis of Chagas disease. Our group has been investigating the participation of this pleiotropic cytokine in different aspects of Chagas disease over the last 20 years. Importan
Externí odkaz:
https://doaj.org/article/6c3830196cbb46bfa0e4b9186f06b89d
Autor:
Florian Robert, Agnès Desroches-Castan, Sabine Bailly, Sophie Dupuis-Girod, Jean-Jacques Feige
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Hereditary Hemorrhagic Telangiectasia (HHT), also known as Rendu-Osler syndrome, is a genetic vascular disorder affecting 1 in 5000–8000 individuals worldwide. This rare disease is characterized by various vascular defects including epista
Externí odkaz:
https://doaj.org/article/58e4a05c1ce9485e874117ded0f49af4
Autor:
Thomas Daubon, Céline Léon, Kim Clarke, Laetitia Andrique, Laura Salabert, Elodie Darbo, Raphael Pineau, Sylvaine Guérit, Marlène Maitre, Stéphane Dedieu, Albin Jeanne, Sabine Bailly, Jean-Jacques Feige, Hrvoje Miletic, Marco Rossi, Lorenzo Bello, Francesco Falciani, Rolf Bjerkvig, Andréas Bikfalvi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Thrombospondin-1 (THSB1) is a component of the ECM with a role in regulating cancer development and tumour vasculature. Here, the authors show that TGF-beta-induced THBS1 expression contributes to the invasive behaviour of GBM cells and promotes resi
Externí odkaz:
https://doaj.org/article/0213114feac44243930602814fc59d30
Autor:
Mariela Subileau, Galina Merdzhanova, Delphine Ciais, Véronique Collin-Faure, Jean-Jacques Feige, Sabine Bailly, Daniel Vittet
Publikováno v:
Stem Cell Reports, Vol 12, Iss 1, Pp 98-111 (2019)
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell
Externí odkaz:
https://doaj.org/article/cbc8f1b0cc9543ffb0a8d475f302b7a3
Autor:
Marie Ouarné, Claire Bouvard, Gabriela Boneva, Christine Mallet, Johnny Ribeiro, Agnès Desroches-Castan, Emmanuelle Soleilhac, Emmanuelle Tillet, Olivier Peyruchaud, Sabine Bailly
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-12 (2018)
Abstract Background Angiogenesis has become an attractive target for cancer therapy. However, despite the initial success of anti-VEGF (Vascular endothelial growth factor) therapies, the overall survival appears only modestly improved and resistance
Externí odkaz:
https://doaj.org/article/eb7e53d2b5f4496c98fedda5fd0bd936
Autor:
Roberto Rodrigues Ferreira, Rayane da Silva Abreu, Glaucia Vilar-Pereira, Wim Degrave, Marcelo Meuser-Batista, Nilma Valéria Caldeira Ferreira, Otacílio da Cruz Moreira, Natália Lins da Silva Gomes, Elen Mello de Souza, Isalira P Ramos, Sabine Bailly, Jean-Jacques Feige, Joseli Lannes-Vieira, Tania C de Araújo-Jorge, Mariana Caldas Waghabi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007602 (2019)
TGF-β involvement in Chagas disease cardiomyopathy has been clearly demonstrated. The TGF-β signaling pathway is activated in the cardiac tissue of chronic phase patients and is associated with an increase in extracellular matrix protein expression
Externí odkaz:
https://doaj.org/article/3736842f86a242e598ff553363a576b7