Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sabine, Schramm"'
Autor:
Oliver Hoffmann, Sebastian Wormland, Ann-Kathrin Bittner, Julian Hölzenbein, Esther Schwich, Sabine Schramm, Hana Rohn, Peter A. Horn, Rainer Kimmig, Sabine Kasimir-Bauer, Vera Rebmann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTriple negative breast cancer (TNBC) shows an aggressive growing and spreading behavior and has limited treatment options, often leading to inferior disease outcome. Therefore, surrogate markers are urgently needed to identify patients at
Externí odkaz:
https://doaj.org/article/1b610616dd9c4983a9d9f684f293205d
Autor:
Hana Rohn, Cordula Lang, Sabine Schramm, Falko M. Heinemann, Mirko Trilling, Anja Gäckler, Oliver Witzke, Peter A. Horn, Vera Rebmann
Publikováno v:
Journal of Immunology Research, Vol 2022 (2022)
The human leukocyte antigen G (HLA-G) is an immune checkpoint molecule with a complex network of interactions with several inhibitory receptors. Although the effect of HLA-G on T cells and NK cells is well studied, the effect of HLA-G on B cells is s
Externí odkaz:
https://doaj.org/article/bc40e9f5db4146bba090e582ad7e2ec0
Autor:
Hana Rohn, Sabine Schramm, Krystallenia Pansikaki, Sarah Jansen, Celina Hendriks, Maximilian Platte, Margarethe J. Konik, Sebastian Dolff, Benjamin Wilde, Lambros Kordelas, Mirko Trilling, Adalbert Krawczyk, Peter A. Horn, Oliver Witzke, Vera Rebmann
The immunosuppressive non-classical human leukocyte antigen-G (HLA-G) can elicits pro-viral activities by down-modulating immune responses. We analysed soluble forms of HLA-G, IL-6 and IL-10 as well as on immune effector cell expression of HLA-G and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87df7862523859148e8f5ecc227b3774
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85152671818
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85152671818
Autor:
Bettina Wagner, Ulrich Dührsen, Andreas Hüttmann, Holger Nückel, Rafael Tomoya Michita, Hana Rohn, Sabine Schramm, Peter A. Horn, Vera Rebmann
Publikováno v:
Cancers, Vol 12, Iss 11, p 3429 (2020)
Aggressive B-cell lymphomas account for the majority of non-Hodgkin lymphomas (B-NHL). NK cells govern the responses to anti-CD20 monoclonal antibodies and have emerged as attractive targets for immunotherapy in subtypes of B-NHL. NKG2C and its cogna
Externí odkaz:
https://doaj.org/article/bdd9024187664859ae8971ddba7b4bbe
Autor:
Hana Rohn, Rafael Tomoya Michita, Sabine Schramm, Sebastian Dolff, Anja Gäckler, Johannes Korth, Falko M. Heinemann, Benjamin Wilde, Mirko Trilling, Peter A. Horn, Andreas Kribben, Oliver Witzke, Vera Rebmann
Publikováno v:
Cells, Vol 8, Iss 8, p 847 (2019)
Human leukocyte antigen (HLA)-E is important for the regulation of anti-viral immunity. BK polyomavirus (BKPyV) reactivation after kidney transplant is a serious complication that can result in BKPyV-associated nephropathy (PyVAN) and subsequent allo
Externí odkaz:
https://doaj.org/article/6b30eb80c17c4d86b3bd6567e58a6df1
Autor:
Rafael Tomoya Michita, José Artur Bogo Chies, Sabine Schramm, Peter A. Horn, Falko M. Heinemann, Andreas Wunsch, Richard Viebahn, Peter Schenker, Vera Rebmann
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2618 (2018)
The polymorphic major histocompatibility complex class I chain-related molecule A (MICA) and its soluble form (sMICA) interact with activating receptor natural-killer group 2 member D (NKG2D) on natural-killer (NK) and T cells, thereby modifying immu
Externí odkaz:
https://doaj.org/article/1e571f645de54350913466e4933bf34e
Autor:
Benjamin Wilde, Peter A. Horn, Sabine Schramm, Anja Gäckler, Falko M. Heinemann, Andreas Kribben, Mirko Trilling, Rafael Tomoya Michita, Esther Schwich, Oliver Witzke, Vera Rebmann, Hana Rohn, Sebastian Dolff, Johannes Korth
The immunosuppressive non-classical human leukocyte antigen-G (HLA-G) promotes transplant tolerance as well as viral immune escape. HLA-G expression is associated with regulatory elements targeting certain single nucleotide polymorphisms (SNPs) in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa1e1e6d4a62c3c156b4d91a664c737
https://www.ncbi.nlm.nih.gov/pubmed/31679637
https://www.ncbi.nlm.nih.gov/pubmed/31679637
Autor:
Sabine Schramm, Johanna Fraune, Ronald Naumann, Abrahan Hernandez-Hernandez, Christer Höög, Howard J Cooke, Manfred Alsheimer, Ricardo Benavente
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002088 (2011)
The synaptonemal complex (SC) is a proteinaceous, meiosis-specific structure that is highly conserved in evolution. During meiosis, the SC mediates synapsis of homologous chromosomes. It is essential for proper recombination and segregation of homolo
Externí odkaz:
https://doaj.org/article/6f8e81dbee0a476b97b30e31fead3c2d
Autor:
Peter A. Horn, Bettina Wagner, Vera Rebmann, Sabine Schramm, Alexander A. Celik, Ulrich Dührsen, Fabiola da Silva Nardi, Jan Dürig, Thomas Kraemer, Holger Nückel
Publikováno v:
Cancer. 123:814-823
BACKGROUND Human leukocyte antigen-E (HLA-E) is a nonclassical major histocompatibility complex class I molecule that recently came into sharper focus as a putative marker of advanced tumor stages and disease progression. In solid tumors, increased H
Autor:
Lisa Zimmer, Antje Sucker, Annette Paschen, Christian U. Blank, Vera Rebmann, J. Utikal, Elisabeth Livingstone, Rudolf A. Herbst, Peter A. Horn, Jürgen C. Becker, Kai Horny, Dirk Schadendorf, Sabine Schramm, Claudia Pföhler, Bastian Schilling, Selma Ugurel
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 31(1)
Programmed cell death protein 1 (PD-1) checkpoint inhibition has recently advanced to one of the most effective treatment strategies in melanoma. Nevertheless, a considerable proportion of patients show upfront therapy resistance and baseline predict