Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Sabine, Middendorp"'
Autor:
Jorik M. van Rijn, Marliek van Hoesel, Cecilia de Heus, AnkeH.M. van Vugt, Judith Klumperman, EdwardE.S. Nieuwenhuis, RoderickH.J. Houwen, Sabine Middendorp
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 10, Pp 1787-1800 (2019)
Dietary lipids are taken up as FAs by the intestinal epithelium and converted by diacylglycerol acyltransferase (DGAT) enzymes into triglycerides, which are packaged in chylomicrons or stored in cytoplasmic lipid droplets (LDs). DGAT1-deficient patie
Externí odkaz:
https://doaj.org/article/87eadb94c84e4ebbb7137284c417f471
Autor:
Jorik M. van Rijn, Marliek van Hoesel, Cecilia de Heus, Anke H.M. van Vugt, Judith Klumperman, Edward E.S. Nieuwenhuis, Roderick H.J. Houwen, Sabine Middendorp
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100126- (2021)
Externí odkaz:
https://doaj.org/article/02e91a3f73974accaf6d9c57598a718c
Autor:
Koos de Wit, Ulrich Beuers, Anna Mukha, Edwin C. A. Stigter, M. Can Gulersonmez, Jose M. Ramos Pittol, Sabine Middendorp, R. Bart Takkenberg, Saskia W. C. van Mil
Publikováno v:
Liver International. 43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e70f0bdbff19ca8cbb296047f09d893
https://doi.org/10.1111/liv.15543
https://doi.org/10.1111/liv.15543
Autor:
Sophie H. Bots, Mira G. P. Zuidgeest, Aisha Gohar, Anouk L. M. Eikendal, Alessandra Petrelli, Harmieke van Os-Medendorp, Marieke F. van der Schaaf, Nina M. van Sorge, Myriam van Wijk, Sabine Middendorp, Caroline M. Speksnijder, Kerstin Klipstein-Grobusch, Vicky Seyfert-Margolis, Esther Mollema, Femke van Wijk, Hester M. den Ruijter
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Despite the recent movements for female equality and empowerment, few women occupy top positions in scientific decision-making. The challenges women face during their career may arise from societal biases and the current scientific culture. We discus
Externí odkaz:
https://doaj.org/article/98361f7b5ff14a7f85b8709b23a7e456
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 2 (2018)
The intestinal epithelium is a highly organized tissue. The establishment of epithelial cell polarity, with distinct apical and basolateral plasma membrane domains, is pivotal for both barrier formation and for the uptake and vectorial transport of n
Externí odkaz:
https://doaj.org/article/b4c0224c3ec6468fa813c995f693afb9
Autor:
Esther Drent, Sabine Middendorp, Andrea Bisso, Sjoerd Baardman, Dagmar Verweij, Estefania Salcedo, Chris Coomans, Steven Braem, Sander van de Weg, Menno Meijer, Natalie Proost, Marieke van de Ven, Haakan Norell, Marleen van Loenen, Nia Emami, Sara Melief, Stefania Gobessi, Mark Throsby
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e0b3dc9baebed5236e465f132a412e8
https://doi.org/10.1136/jitc-2022-sitc2022.0215
https://doi.org/10.1136/jitc-2022-sitc2022.0215
Autor:
Lydia S. Schulla, E. Diana Alupoaie, Leanne De Silva, Debby Gawlitta, Sabine Middendorp, Paul J. Coffer, M. Guy Roukens
Organoids hold great potential for regenerative medicine and biomedical research. While they are able to recapitulate many structural and functional aspects of their in vivo counterparts, they lack a functional vasculature. In this study, we aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8803f1c2017c6ec6a3b7e09bf4d6fd94
https://doi.org/10.1101/2022.03.25.485813
https://doi.org/10.1101/2022.03.25.485813
Autor:
Kelly F. Meijsen, Hugo R. de Jonge, Antje Ballauff, Anke H M van Vugt, Roderick H. J. Houwen, Manuel B Bryant, Thomas Müller, Sabine Middendorp, Tanja Restin, Marcel J. C. Bijvelds, Andreas R. Janecke, Bart G. P. Koot
Publikováno v:
Clinical and Translational Gastroenterology, 12(11):e00427. Nature Publishing Group
van Vugt, A H M, Bijvelds, M J C, de Jonge, H R, Meijsen, K F, Restin, T, Bryant, M B, Ballauff, A, Koot, B, Müller, T, Houwen, R H J, Janecke, A R & Middendorp, S 2021, ' A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 12, no. 11, pp. e00427 . https://doi.org/10.14309/ctg.0000000000000427
Clinical and translational gastroenterology, 12(11). Nature Publishing Group
Clinical and Translational Gastroenterology
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 12(11). Nature Publishing Group
van Vugt, A H M, Bijvelds, M J C, de Jonge, H R, Meijsen, K F, Restin, T, Bryant, M B, Ballauff, A, Koot, B, Müller, T, Houwen, R H J, Janecke, A R & Middendorp, S 2021, ' A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 12, no. 11, pp. e00427 . https://doi.org/10.14309/ctg.0000000000000427
Clinical and translational gastroenterology, 12(11). Nature Publishing Group
Clinical and Translational Gastroenterology
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 12(11). Nature Publishing Group
INTRODUCTION: Gain-of-function mutations in guanylyl cyclase C (GCC) result in persistent diarrhea with perinatal onset. We investigated a specific GCC inhibitor, SSP2518, for its potential to treat this disorder. METHODS: We investigated the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d3192ebcfb634acea304772d3b318e
https://pure.eur.nl/en/publications/476a3967-0cd2-4270-92cc-95c7bcb17260
https://pure.eur.nl/en/publications/476a3967-0cd2-4270-92cc-95c7bcb17260
Autor:
Pieter P E van Lierop, Sigrid M Swagemakers, Charlotte I de Bie, Sabine Middendorp, Peter van Baarlen, Janneke N Samsom, Wilfred F J van Ijcken, Johanna C Escher, Peter J van der Spek, Edward E S Nieuwenhuis
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79549 (2013)
ObjectiveIn current clinical practice, optimal treatment of inflammatory bowel disease (IBD) aims at the induction and maintenance of clinical remission. Clinical remission is apparent when laboratory markers of inflammation are normal and clinical s
Externí odkaz:
https://doaj.org/article/efa5ee04a5654b7d8d2d142109cfe77b
Autor:
Sabine A. Fuchs, Hoa Truong, Hans C. Gerritsen, Kerstin Schneeberger, Peter G.J. Nikkels, Edward E. S. Nieuwenhuis, Michal Mokry, Rúben J.J. Ramos, Michel van Weeghel, Hans Clevers, Sabine Middendorp, Dave J. van den Heuvel, Meritxell Huch, Bart Spee, Peter M. van Hasselt, Imre F. Schene, Riekelt H. Houtkooper, Anke H.M. van Vugt
Publikováno v:
SSRN Electronic Journal.
Aerobic glycolysis, characterized by pyruvate reduction to lactate, serves proliferation in cancer cells and stem cells. To clarify whether this metabolic profile is universal to epithelial stem cells, despite vast differences in physiological turnov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43cb5e93916551ee0c9abcfee8bcaec8
https://doi.org/10.2139/ssrn.3564994
https://doi.org/10.2139/ssrn.3564994