Výsledky vyhledávání - "Sabine, Kopf"

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin

Publikováno v: Archives of Toxicology
Archives of Toxicology; Vol 87

Metastases destroy the function of infested organs and are the main reason of cancer-related mortality. Heteronemin, a natural product derived from a marine sponge, was tested in vitro regarding its properties to prevent tumour cell intravasation thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad58298f4e78e479f0fc69e9e58c877
https://doi.org/10.1007/s00204-013-1045-1

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Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

Publikováno v: Archives of Toxicology; Vol 87
Archives of Toxicology

Health beneficial effects of xanthohumol have been reported, and basic research provided evidence for anti-cancer effects. Furthermore, xanthohumol was shown to inhibit the migration of endothelial cells. Therefore, this study investigated the anti-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcb8f1d4fe72243725f66ee81585c21

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Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion

Publikováno v: British Journal of Cancer; Vol 108
British Journal of Cancer

Background: Many cancers spread through lymphatic routes, and mechanistic insights of tumour intravasation into the lymphatic vasculature and targets for intervention are limited. The major emphasis of research focuses currently on the molecular biol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc28792917484b5c200d8671d0882222

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[Relapsing fever: an almost forgotten disease in focus again]

Autor: Andreas, Wieser, Thomas, Löscher, Mirjam, Schunk, Michael, Seilmaier, Lukas, Balzer, Gabriele, Margos, Ulrich, von Both, Thomas, Schulzki, Sabine, Kopf, Martin, Hoch, Andreas, Sing, Volker, Fingerle

Publikováno v: Deutsche medizinische Wochenschrift (1946). 141(14)

Introduction | Relapsing fevers, transmitted by arthropods, are rarely encountered in Germany, thus they are often not considered as differential diagnosis in febrile patients. In the last months, more than fourty cases of louse-borne relapsing fever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a34d8f6702ad1fdb7f2e65b87a024bf5
https://pubmed.ncbi.nlm.nih.gov/27404930

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Inhibition of tumour spheroid-induced prometastatic intravasation gates in the lymph endothelial cell barrier by carbamazepine: drug testing in a 3D model

Autor: Nicole Kretschy, Verena M. Dirsch, Kanokwan Jarukamjorn, Philipp Saiko, Georg Krupitza, Wolfgang Mikulits, Benedikt Giessrigl, Michael Grusch, Helmut Dolznig, Nicole Huttary, Walter Jäger, Katharina Viola, Sigurd Krieger, Thomas Szekeres, Atanas G. Atanasov, Mathias Teichmann, Sabine Kopf

Publikováno v: Archives of Toxicology.

Metastatic breast cancer is linked to an undesired prognosis. One early and crucial metastatic step is the interaction of cancer emboli with adjacent stroma or endothelial cells, and understanding the mechanisms of this interaction provides the basis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a215a7e564331d68ad5b413d08d46406
https://doi.org/10.1007/s00204-013-1183-5

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In vitro inhibition of breast cancer spheroid-induced lymphendothelial defects resembling intravasation into the lymphatic vasculature by acetohexamide, isoxsuprine, nifedipin and proadifen

Autor: Benedikt Giessrigl, Caroline Vonach, Philipp Saiko, Michael Grusch, Helmut Dolznig, Sabine Kopf, Verena M. Dirsch, Sebastian M.B. Nijman, Nicole Kretschy, Wolfgang Mikulits, Georg Krupitza, Katharina Viola, Sigurd Krieger, Thomas Szekeres, Atanas G. Atanasov, Ingrid Raab, Mathias Teichmann, Nicole Huttary, Walter Jäger

Publikováno v: British Journal of Cancer
British Journal of Cancer; Vol 108

BACKGROUND: As metastasis is the prime cause of death from malignancies, there is vibrant interest to discover options for the management of the different mechanistic steps of tumour spreading. Some approved pharmaceuticals exhibit activities against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b05dfa470972eaaab13fbf0e0ef4a8
http://ora.ox.ac.uk/objects/uuid:cdd39b5b-c27d-4f2d-81c2-1c38e86f8bb0

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Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells

Autor: Markus Hengstschläger, Sigurd Krieger, Samir Messaoudi, Benedikt Giessrigl, Sabine Kopf, Michaela Gollinger, Jean-François Peyrat, Thomas Szekeres, Nicole Huttary, Walter Jäger, Mouad Alami, Alexandre Maciuk, Margit Rosner, Peter R. Mazal, Daumantas Matulis, Egidijus Kazlauskas, Georg Krupitza, Philipp Saiko

Publikováno v: Human molecular genetics. 21(21)

Pancreas cancer cells escape most treatment options. Heat shock protein (Hsp)90 is frequently over-expressed in pancreas carcinomas and protects a number of cell-cycle regulators such as the proto-oncogene Cdc25A. We show that inhibition of Hsp90 wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ab8ab1c79184af6cdc63062957dddb
https://pubmed.ncbi.nlm.nih.gov/22843495

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Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

Autor: Michael Grusch, Walter Jäger, Ali Özmen, Verena M. Dirsch, Georg Krupitza, Mathias Teichmann, Benedikt Giessrigl, Sabine Kopf, Gökhan Yazici, Atanas G. Atanasov, Sara Ghassemi

Publikováno v: International Journal of Oncology.

Different studies describe the anti-inflammatory effects of Scrophularia species, a medicinal plant widely used in folk medicine since ancient times. As knowledge regarding the anti-neoplastic properties of this species is rather limited, we investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e665868d0a233c731c0396942853d34b
https://doi.org/10.3892/ijo.2012.1388

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A poling study of lead zirconate titanate∕polyurethane 0–3 composites

Autor: Kin Wing Kwok, Sabine Kopf, Sien Ting Lau, Franklin G. Shin

Publikováno v: Journal of Applied Physics. 102:044104

0–3 composites of lead zirconate titanate particles dispersed in a thermoplastic elastomer polyurethane matrix were fabricated. The dielectric permittivity and loss of the composite film were measured and compared to the theoretical values. The com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ee3c38ed84585c0cb4cf91f0c7d90ee
https://doi.org/10.1063/1.2767614

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