Výsledky vyhledávání - "Sabine, Gröbner"

Surface-associated motility, a common trait of clinical isolates of Acinetobacter baumannii, depends on 1,3-diaminopropane

Autor: Paul G. Higgins, Ortrud Zimmermann, Yvonne Pfeifer, Bettina Hammer, Daniela Lepka, Evelyn Skiebe, Véronique de Berardinis, Hans-Jürgen Busse, Gottfried Wilharm, Harald Seifert, Franziska Faber, Sabine Gröbner, Thomas A. Wichelhaus, Stefan Ziesing, Klaus-Peter Hunfeld, Stefan Borgmann, Tobias Kerrinnes, Wolfgang Witte, Peter Morczinek

Publikováno v: International Journal of Medical Microbiology. 302:117-128

While flagella-independent motility has long been described in representatives of the genus Acinetobacter, the mechanism of motility remains ambiguous. Acinetobacter baumannii, a nosocomial pathogen appearing increasingly multidrug-resistant, may pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4211ce31325bda836de9928bda39b5a
https://doi.org/10.1016/j.ijmm.2012.03.003

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Lysozyme facilitates adherence of Enterococcus faecium to host cells and induction of necrotic cell death

Autor: Steffen Höring, Monika Schütz, Sabine Gröbner, Ingo B. Autenrieth

Publikováno v: Microbes and Infection. 14:554-562

The prevalence of infections with enterococci is increasing worldwide. However, little is known about the mechanisms which enable these opportunistic pathogens to cause infections of their host. Here we demonstrate that Enterococcus faecium in the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0b8b93bd20b990b6d1f11cd9a73b5e
https://doi.org/10.1016/j.micinf.2012.01.005

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In vitro Activity of Tigecycline and Molecular Characterization of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates from a University Hospital in South-Western Germany

Autor: Matthias Wienke, Patrick Weissgerber, Ingo B. Autenrieth, Matthias Marschal, Sabine Gröbner, Yvonne Pfeifer

Publikováno v: Chemotherapy. 58:241-248

Background: Extended-spectrum β-lactamase (ESBL)-producing organisms are spreading worldwide in hospital and community settings. Methods: A total of 328 unduplicated ESBL-producing Enterobacteriaceae isolated in 2008 and 2009 at the University Hospi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d79fbc46859db2542698a558248759ef
https://doi.org/10.1159/000339488

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Lysozyme activates Enterococcus faecium to induce necrotic cell death in macrophages

Autor: Evelyn Fritz, Ingo B. Autenrieth, Martin Schaller, Alexander Berger, Friederike Schoch, Michael Bitzer, Sabine Gröbner

Publikováno v: Cellular and Molecular Life Sciences. 67:3331-3344

Enterococci are commensal organisms in the alimentary tract. However, they can cause a variety of life-threatening infections, especially in nosocomial settings. We hypothesized that induction of cell death might enable these facultative pathogenic b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f7ab699be8e214881cd82731fcde45
https://doi.org/10.1007/s00018-010-0384-9

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Emergence of carbapenem-non-susceptible extended-spectrum β-lactamase-producing Klebsiella pneumoniae isolates at the university hospital of Tübingen, Germany

Autor: Wolfgang Witte, Sabine Gröbner, Johannes Madlung, Yvonne Pfeifer, Dirk Linke, Ingo B. Autenrieth, Claudia Fladerer, Wolfgang Schütz

Publikováno v: Journal of Medical Microbiology. 58:912-922

The spread of Gram-negative bacteria with plasmid-borne extended-spectrumβ-lactamases (ESBLs) has become a worldwide problem. This study analysed a total of 366 ESBL-producingEnterobacteriaceaestrains isolated from non-selected patient specimens at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7875427d90a0019b2255ec45a6a72b56
https://doi.org/10.1099/jmm.0.005850-0

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Evaluation of the BD GeneOhm StaphSR Assay for Detection of Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates from Spiked Positive Blood Culture Bottles

Autor: Volkhard A. J. Kempf, Sabine Gröbner, Mélanie Plante, Mireille Dion

Publikováno v: Journal of Clinical Microbiology. 47:1689-1694

To improve the clinical outcome of Staphylococcus aureus septicemia, the early selection of appropriate antibiotic treatment is crucial. Molecular diagnostics represents an attractive approach for the rapid identification of S. aureus and the determi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa123f9649dc51241ee642746b471ce7
https://doi.org/10.1128/jcm.02179-08

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Y. enterocolitica inhibits antigen degradation in dendritic cells

Autor: Stefan Borgmann, Sabine Gröbner, Erwin Bohn, Ingo B. Autenrieth, Martin Köberle, Irena Adkins, Stella E. Autenrieth

Publikováno v: Microbes and Infection. 10:798-806

Yersinia enterocolitica (Ye) disrupts the ability of dendritic cells (DC) to prime CD4+ T cells suggesting that Ye may subvert uptake and/or processing of soluble antigens (Ag). To investigate this Ye-infected DC were loaded with fluorescently labell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1c720b5390673648e320daff8e715f
https://doi.org/10.1016/j.micinf.2008.04.014

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Differential roles of Yersinia outer protein P-mediated inhibition of nuclear factor-kappa B in the induction of cell death in dendritic cells and macrophages

Autor: Sabine Gröbner, Ingo B. Autenrieth, Sebastian Schulz, Stefan Borgmann, Irena Adkins

Publikováno v: Journal of Medical Microbiology. 57:139-144

Yersinia outer protein P (YopP) induces cell death in macrophages and dendritic cells (DC). In DC this YopP-dependent cell death coincides with the inhibition of nuclear factor-kappa B (NF-κB) activation. However, as shown by measurement of propidiu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11fcae6e10cc227dc67ddeb3c99d5be
https://doi.org/10.1099/jmm.0.47437-0

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Absence of Toll-Like Receptor 4 Signaling Results in Delayed Yersinia enterocolitica YopP-Induced Cell Death of Dendritic Cells

Autor: Dani S. J. Gunst, Sebastian Wesselborg, Irena Soldanova, Ingo B. Autenrieth, Michaela Waibel, Sabine Gröbner, Stefan Borgmann, Sebastian Schulz

Publikováno v: Infection and Immunity. 75:512-517

In an initial period (≤4 h) Toll-like receptor 4 (TLR4) signaling is required for Yersinia enterocolitica YopP-induced dendritic cell (DC) death. Later (>4 h), DC die independent of TLR4 signaling. In TLR4-deficient DC caspase 8 cleavage is delayed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e5e8ad3d847b472b6ea85f4b51164d
https://doi.org/10.1128/iai.00756-06

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Yersinia enterocoliticaInduces Apoptosis and Inhibits Surface Molecule Expression and Cytokine Production in Murine Dendritic Cells

Autor: Irena Soldanova, Martin Schaller, Uwe Kramer, Stefan Borgmann, Stella E. Erfurth, Sabine Gröbner, Dani S. J. Gunst, Ingo B. Autenrieth

Publikováno v: Infection and Immunity. 72:7045-7054

Yersinia enterocoliticaevades innate immunity by expression of a variety of pathogenicity factors. Therefore, adaptive immunity including CD4+T cells plays an important role in defense againstY. enterocolitica. We investigated whetherY. enterocolitic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981a9e81888d8610783618ce0eef5d8a
https://doi.org/10.1128/iai.72.12.7045-7054.2004

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