Výsledky vyhledávání - "Sabina Palma"

RHBDD2‑WWOX protein interaction during proliferative and differentiated stages in normal and breast cancer cells

Autor: Ezequiel Lacunza, Valeria Alejandra Ferretti, Sabina Palma, Claudio M Aldaz, Romina Canzoneri, Martín Carlos Abba

Publikováno v: Oncology Reports. 46

Rhomboid pseudoproteases are catalytically inactive members of the rhomboid superfamily that modulate the traffic, turnover and activity of their target proteins. Rhomboid domain containing 2 (RHBDD2) is a rhomboid family member overexpressed during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d60fec0f6a3a771e7699cbcd271df5
https://doi.org/10.3892/or.2021.8108

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Rol del gen RHBDD2 en la progresión del cáncer colorrectal frente al tratamiento neoadyuvante

Autor: Sabina Palma

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

El cáncer colorrectal (CCR) es una enfermedad frecuentemente letal con pronóstico y respuesta al tratamiento heterogéneos. Estas diferencias residen en las características moleculares intrínsecas de los tumores. Los pacientes con cáncer de rect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8dfe00a93a89a005f20239d604c1b29
http://sedici.unlp.edu.ar/handle/10915/115241

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RHBDD2 overexpression promotes a chemoresistant and invasive phenotype to rectal cancer tumors via modulating UPR and focal adhesion genes

Autor: Maria B. Garcia-Fabiani, Ariel Osvaldo Zwenger, Martín Carlos Abba, C.I. Raffa, E. Rojas Bilbao, Ezequiel Lacunza, Valeria Alejandra Ferretti, P.V. Perez Verdera, Sabina Palma, A. Llontop, V. Cuartero

Publikováno v: Biochimica et biophysica acta. Molecular basis of disease. 1866(8)

The current standard of care for locally advanced rectal cancer (RC) is neoadjuvant radio-chemotherapy (NRC) with 5-fluorouracil (5Fu) as the main drug, followed by surgery and adjuvant chemotherapy. While a group of patients will achieve a pathologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d5b817fc82094aab7316194f151ac9
https://pubmed.ncbi.nlm.nih.gov/32339641

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Alternative splicing variant of RHBDD2 is associated with cell stress response and breast cancer progression

Autor: Valeria Alejandra Ferretti, Ezequiel Lacunza, Sabina Palma, María Virginia Croce, Martín Enrique Rabassa, Romina Canzoneri, Martín Carlos Abba, Marina Teresita Isla Larrain, Agustina Gurruchaga

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

RHBDD2 is an intramembrane pseudoprotease member of the Rhomboid superfamily. Our previous studies in breast and colorectal cancer indicate an association between RHBDD2 overexpression and advanced tumor stages. Two alternative transcriptional varian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121ab067e04e785889c06c76b1db2492
https://doi.org/10.3892/or.2018.6489

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From Molecular Biology to Clinical Trials: Toward Personalized Colorectal Cancer Therapy

Autor: Martín Carlos Abba, Ariel Osvaldo Zwenger, María Virginia Croce, Sabina Palma, Ezequiel Lacunza

During the past years, molecular studies through high-throughput technologies have led to the confirmation of critical alterations in colorectal cancer (CRC) and the discovery of some new ones, including mutations, DNA methylations, and structural ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2627c53c7cef01eb6f310d54d5d0519d
https://www.sciencedirect.com/science/article/pii/S1533002815001462

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