Výsledky vyhledávání - "Sabina Nivelius"

Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime

Autor: Xue-Qing Li, Inger Johansson, Tommy B. Andersson, Åsa Nordling, Sabina Nivelius, Yvonne Hofmann, Magnus Ingelman-Sundberg, Susanne Andersson

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 33(4)

The enzymic basis for intracellular reduction of N-hydroxylated amidines to their corresponding amidines, and hydroxylamines to their corresponding amines, is unknown. The hydroxylated amidines can be used as prodrug moieties, and an understanding of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd731a36ef6853a2491c4d9db8de8be5
https://pubmed.ncbi.nlm.nih.gov/15640373

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Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis

Autor: Inger Johansson, Sabina Nivelius, Niklas Lindegårdh, Yngve Bergqvist, Michael Ashton, Mita M. Thapar, Anders Björkman

Publikováno v: European journal of clinical pharmacology. 58(1)

OBJECTIVE: To determine the pharmacokinetic profiles of atovaquone (ATO), proguanil (PROG) and its active metabolite cycloguanil (CYCLO) with respect to possible accumulation and kinetic interaction upon repeated dosing with Malarone. METHODS: Thirte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a73143a7fade1acd2d11373e68d7cda7
https://pubmed.ncbi.nlm.nih.gov/11956669

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