Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sabina, Schütz"'
Autor:
A. Leoni Swart, Bernhard Steiner, Laura Gomez-Valero, Sabina Schütz, Mandy Hannemann, Petra Janning, Michael Irminger, Eva Rothmeier, Carmen Buchrieser, Aymelt Itzen, Vikram Govind Panse, Hubert Hilbi
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Legionella pneumophila governs its interactions with host cells by secreting >300 different “effector” proteins. Some of these effectors contain eukaryotic domains such as the RCC1 (regulator of chromosome condensation 1) repeats promoti
Externí odkaz:
https://doaj.org/article/b6a4a85bf46b4fbaa5aaf3dcedc0ad39
Autor:
Sabina Schütz, Erich Michel, Fred F. Damberger, Michaela Oplová, Cohue Peña, Alexander Leitner, Ruedi Aebersold, Frederic H.-T. Allain, Vikram Govind Panse
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Ribosomal proteins are transported to the nucleus with the help of importins, from which they are released prior to incorporation into the nascent ribosome. Here the authors report the NMR structure of the ribosomal protein eS26 in complex with the e
Externí odkaz:
https://doaj.org/article/6a9a3ed39ff54d0fae4c92979ac96f5c
Publikováno v:
eLife, Vol 5 (2016)
Spatial clustering of ribosomal proteins (r-proteins) through tertiary interactions is a striking structural feature of the eukaryotic ribosome. However, the functional importance of these intricate inter-connections, and how they are established is
Externí odkaz:
https://doaj.org/article/c56a425fd3ce4102acdcb854c5e34de7
Autor:
Martin Altvater, Yiming Chang, Andre Melnik, Laura Occhipinti, Sabina Schütz, Ute Rothenbusch, Paola Picotti, Vikram Govind Panse
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-15 (2012)
Abstract Construction and intracellular targeting of eukaryotic pre‐ribosomal particles involve a multitude of diverse transiently associating trans‐acting assembly factors, energy‐consuming enzymes, and transport factors. The ability to rapidl
Externí odkaz:
https://doaj.org/article/5baec9dd89064d3697616d717942ed4e
Autor:
Ute Fischer, Nico Schäuble, Sabina Schütz, Martin Altvater, Yiming Chang, Marius Boulos Faza, Vikram Govind Panse
Publikováno v:
eLife, Vol 4 (2015)
The transport receptor Crm1 mediates the export of diverse cargos containing leucine-rich nuclear export signals (NESs) through complex formation with RanGTP. To ensure efficient cargo release in the cytoplasm, NESs have evolved to display low affini
Externí odkaz:
https://doaj.org/article/3788bc4e02ab456db0832c7086b6c838
Autor:
Sabina Schütz, Ute Fischer, Martin Altvater, Purnima Nerurkar, Cohue Peña, Michaela Gerber, Yiming Chang, Stefanie Caesar, Olga T Schubert, Gabriel Schlenstedt, Vikram G Panse
Publikováno v:
eLife, Vol 3 (2014)
Within a single generation time a growing yeast cell imports ∼14 million ribosomal proteins (r-proteins) into the nucleus for ribosome production. After import, it is unclear how these intrinsically unstable and aggregation-prone proteins are targe
Externí odkaz:
https://doaj.org/article/3fc393b43bdf4756972fac031e350d97
Autor:
A Leoni, Swart, Bernhard, Steiner, Laura, Gomez-Valero, Sabina, Schütz, Mandy, Hannemann, Petra, Janning, Michael, Irminger, Eva, Rothmeier, Carmen, Buchrieser, Aymelt, Itzen, Vikram Govind, Panse, Hubert, Hilbi
Publikováno v:
mBio
Legionella pneumophila is a ubiquitous environmental bacterium which, upon inhalation, causes a life-threatening pneumonia termed Legionnaires’ disease. The opportunistic pathogen grows in amoebae and macrophages by employing a “type IV” secret
Autor:
Leif S. Ludwig, Jacob C. Ulirsch, Vikram Govind Panse, Steven A. Carr, D. R. Mani, Harrison Specht, Mathias Munschauer, Hanna T. Gazda, Olga K. Weinberg, Claudia Fiorini, Jesse M. Engreitz, Hasmik Keshishian, Sean K. McFarland, Karen W. Gripp, Aviv Regev, Winston Y. Lee, Vijay G. Sankaran, Geraldine S. Pinkus, Nour J. Abdulhay, John Lian, Rajiv K. Khajuria, Lee Gehrke, Steven R. Ellis, Charles P. Fulco, Eric S. Lander, Marko Jovanovic, Sabina Schütz
Publikováno v:
PMC
Blood cell formation is classically thought to occur through a hierarchical differentiation process, although recent studies have shown that lineage commitment may occur earlier in hematopoietic stem and progenitor cells (HSPCs). The relevance to hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77f85830d56ed22ec311e075d0ca096
https://europepmc.org/articles/PMC5866246/
https://europepmc.org/articles/PMC5866246/
Publikováno v:
eLife, Vol 5 (2016)
eLife, 5
eLife
eLife, 5
eLife
Spatial clustering of ribosomal proteins (r-proteins) through tertiary interactions is a striking structural feature of the eukaryotic ribosome. However, the functional importance of these intricate inter-connections, and how they are established is