Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Sabina, Podlewska"'
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-27 (2023)
Abstract Graph neural networks have recently become a standard method for analyzing chemical compounds. In the field of molecular property prediction, the emphasis is now on designing new model architectures, and the importance of atom featurization
Externí odkaz:
https://doaj.org/article/fd17a7dd86344f909f5397f815e16f8c
Autor:
Karolina Witek, Aneta Kaczor, Ewa Żesławska, Sabina Podlewska, Małgorzata Anna Marć, Kinga Czarnota-Łydka, Wojciech Nitek, Gniewomir Latacz, Waldemar Tejchman, Markus Bischoff, Claus Jacob, Jadwiga Handzlik
Publikováno v:
Antibiotics, Vol 12, Iss 11, p 1618 (2023)
In this study, a search for new therapeutic agents that may improve the antibacterial activity of conventional antibiotics and help to successfully overcome methicillin-resistant Staphylococcus aureus (MRSA) infections has been conducted. The purpose
Externí odkaz:
https://doaj.org/article/b86e873063524db1aa3c92b6214f256f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5639-5651 (2022)
Physicochemical and pharmacokinetic compound profile has crucial impact on compound potency to become a future drug. Ligands with desired activity profile cannot be used for treatment if they are characterized by unfavourable physicochemical or ADMET
Externí odkaz:
https://doaj.org/article/122eb4aa13af43169311af6067833e1a
Publikováno v:
Journal of Cheminformatics, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background Computational methods support nowadays each stage of drug design campaigns. They assist not only in the process of identification of new active compounds towards particular biological target, but also help in the evaluation and op
Externí odkaz:
https://doaj.org/article/3f207c380c1b4fb3b01b4b62d3198d19
Autor:
Hanna Baltrukevich, Sabina Podlewska
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
An increasing number of crystal structures available on one side, and the boost of computational power available for computer-aided drug design tasks on the other, have caused that the structure-based drug design tools are intensively used in the dru
Externí odkaz:
https://doaj.org/article/236943a9fa784c808922900c4b35c122
Autor:
Alina Minias, Lidia Żukowska, Ewelina Lechowicz, Filip Gąsior, Agnieszka Knast, Sabina Podlewska, Daria Zygała, Jarosław Dziadek
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of people worldwide. Mycobacterium tuberculosis is an intracellular pathogen with an
Externí odkaz:
https://doaj.org/article/054f02538a84414aa3199edbd980dd0b
Autor:
Lucja Kudla, Ryszard Bugno, Sabina Podlewska, Lukasz Szumiec, Lucja Wiktorowska, Andrzej J. Bojarski, Ryszard Przewlocki
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 55 (2021)
Among different approaches to the search for novel—safer and less addictive—opioid analgesics, biased agonism has received the most attention in recent years. Some μ-opioid receptor agonists with G protein bias, including SR compounds, were prop
Externí odkaz:
https://doaj.org/article/bb245714fddc472f878e903337a1c137
Autor:
Katarzyna Kucwaj-Brysz, Anna Dela, Sabina Podlewska, Marek Bednarski, Agata Siwek, Grzegorz Satała, Kinga Czarnota, Jadwiga Handzlik, Katarzyna Kieć-Kononowicz
Publikováno v:
Molecules, Vol 26, Iss 22, p 7025 (2021)
Several studies confirmed the reciprocal interactions between adrenergic and serotoninergic systems and the influence of these phenomena on the pathogenesis of anxiety. Hence, searching for chemical agents with a multifunctional pharmacodynamic profi
Externí odkaz:
https://doaj.org/article/c378d5c166f349a6af1c3d5be2fa4bf7
Publikováno v:
Journal of Chemical Information and Modeling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3b52ab4d6c77810f2dab6e5398e085
https://doi.org/10.1021/acs.jcim.2c01355
https://doi.org/10.1021/acs.jcim.2c01355
Autor:
Enza Lacivita, Imane Ghafir El Idrissi, Sabina Podlewska, Carmen Abate, Andrzej J. Bojarski, Marcello Leopoldo
Publikováno v:
Current Medicinal Chemistry. 30
Abstract: The purinergic P2X7 receptor (P2X7R), an ATP-gated non-selective cation channel, has emerged as a gatekeeper of inflammation that controls the release of pro-inflammatory cytokines. As a key player in initiating the inflammatory signaling c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64b0e93bb9da58ecd36631798c5eb83f
https://doi.org/10.2174/0929867330666230403094538
https://doi.org/10.2174/0929867330666230403094538