Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Sabina, Eigenbrod"'
Autor:
Sebastian Siller, Michael Lauseker, Philipp Karschnia, Maximilian Niyazi, Sabina Eigenbrod, Armin Giese, Joerg-Christian Tonn
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract MGMT-promoter methylation is associated with favorable outcome in glioblastoma. The aim of this study was to determine whether the absolute number of methylated Cytosine-Guanine-dinucleotide-(CpG-)sites within the DMR-2 island of the MGMT-pr
Externí odkaz:
https://doaj.org/article/0462d463d218450c89160211d9939593
Autor:
Sabina Eigenbrod, Petra Frick, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, Janina Mielke, Marko Maringer, Niklas Piening, Alexander Hepp, Nathalie Daude, Otto Windl, Johannes Levin, Armin Giese, Vignesh Sakthivelu, Jörg Tatzelt, Hans Kretzschmar, David Westaway
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites within the
Externí odkaz:
https://doaj.org/article/768e6387c51240a48de92b6362f601c9
Autor:
Nathalie L. Jansen, Bogdana Suchorska, Silke B. Schwarz, Sabina Eigenbrod, Juergen Lutz, Vera Graute, Peter Bartenstein, Claus Belka, Friedrich W. Kreth, Christian la Fougère
Publikováno v:
Molecular Imaging, Vol 12 (2013)
Therapy monitoring of glioma after stereotactic iodine-125 brachytherapy (SBT) remains challenging because posttherapeutic changes in magnetic resonance imaging can mimic tumor progression. We evaluated the prognostic value of serial [ 18 F]fluoroeth
Externí odkaz:
https://doaj.org/article/da3ca7694f5d4e7480b0af5adfc5dc63
Autor:
Sabina Eigenbrod, Niklas Thon, Nathalie Jansen, Hendrik Janssen, Janina Mielke, Michael Ruiter, Christian la Fougère, Aurelia Peraud, Rupert Egensperger, Hans Kretzschmar
Publikováno v:
Rare Tumors, Vol 4, Iss 2, Pp e30-e30 (2012)
Intramedullary glioma are rare and their biological behaviour can differ from their cerebral counterparts. Pilomyxoid astrocytoma (PMA, WHO grade II), predominantly occur in the hypothalamic/chiasmatic region of infants and children. The few reported
Externí odkaz:
https://doaj.org/article/ced129ffcdc5483090394d46357efb9f
Autor:
Oliver Schnell, Alexander Romagna, Irene Jaehnert, Valerie Albrecht, Sabina Eigenbrod, Kathrin Juerchott, Hans Kretzschmar, Jörg-Christian Tonn, Christian Schichor
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30429 (2012)
Krüppel-like factor 8 (KLF8) has only recently been identified to be involved in tumor cell proliferation and invasion of several different tumor entities like renal cell carcinoma, hepatocellular carcinoma and breast cancer. In the present study, w
Externí odkaz:
https://doaj.org/article/9dff591685cf4358bff3125f8aab0570
Autor:
Simone Kreth, Niklas Thon, Sabina Eigenbrod, Juergen Lutz, Carola Ledderose, Rupert Egensperger, Joerg C Tonn, Hans A Kretzschmar, Ludwig C Hinske, Friedrich W Kreth
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17156 (2011)
BackgroundWe analyzed prospectively whether MGMT (O(6)-methylguanine-DNA methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT promoter methylation in malignant glioma patients undergoing radiotherapy with concomit
Externí odkaz:
https://doaj.org/article/fa23620181d841498032e6d200ad0302
Autor:
Ke-Tai Guo, Jun Thorsteinsdottir, Christian Schichor, Jörg-Christian Tonn, Stefan Stangl, Sabina Eigenbrod, Mathias Gehrmann, Janina Erl, Valerie Albrecht, Gabriele Multhoff, Peng Fu
Publikováno v:
Journal of Neuro-Oncology. 135:443-452
A unique feature in several non-CNS-tumors is the overexpression of heat shock protein 70 (Hsp70, HSPA1A) in the cytosol, but also its unusual plasma membrane expression and release. Although in gliomas, cytosolic Hsp70 levels are not associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f3971892e87c78ccc6d58c10fcfb42
https://doi.org/10.1007/s11060-017-2600-z
https://doi.org/10.1007/s11060-017-2600-z
Autor:
Hans A. Kretzschmar, Marko Maringer, Nathalie Daude, Alexander Hepp, David Westaway, Gerda Mitteregger-Kretzschmar, Janina Mielke, Sabina Eigenbrod, Armin Giese, Petra Frick, Vignesh Sakthivelu, Jörg Tatzelt, Uwe Bertsch, Otto Windl, Niklas Piening, Johannes Levin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
PLOS ONE 12(12), e0188989 (2017). doi:10.1371/journal.pone.0188989
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
PLOS ONE 12(12), e0188989 (2017). doi:10.1371/journal.pone.0188989
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe04532615df3576b97bd80efd02003
https://pubmed.ncbi.nlm.nih.gov/29220360
https://pubmed.ncbi.nlm.nih.gov/29220360
Autor:
Hans A. Kretzschmar, Friedrich-Wilhelm Kreth, Niklas Thon, Mathias Kunz, Jochen Herms, Sabina Eigenbrod, Armin Giese, Jörg-Christian Tonn, Nathalie Jansen, Rupert Egensperger, Simone Kreth, Michael Weller, Lena Lemke, Christian la Fougère, Jürgen Lutz
Publikováno v:
International Journal of Cancer. 136:2132-2145
In suspected grade II gliomas, three distinct patterns of time-activity curves (TAC) on O-(2-[(18)F]fluoroethyl)-1-tyrosine ((18)F-FET) positron emission tomography (PET) have been delineated (i) increasing TAC homogeneously throughout the tumor, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a405c999d406e945088bfc7df2091fc
https://doi.org/10.1002/ijc.29259
https://doi.org/10.1002/ijc.29259
Autor:
Stefan Zausinger, Friedrich W. Kreth, Hans A. Kretzschmar, Stephan Dützmann, Jörg C. Tonn, Guenther C. Feigl, Niklas Thon, Natalia Kremenevskaja, Matthias Simon, Sabina Eigenbrod, Walter Rachinger
Publikováno v:
Journal of Neurosurgery. 120:1313-1320
Object Chordomas of the skull base are rare and locally invasive and have a poor prognosis. The aim of this retrospective multicenter study was to evaluate the current pattern of care and clinical course and to identify prognostic factors. Methods A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630b8b90fb4b35886d7c6607738bbe0a
https://doi.org/10.3171/2013.11.jns131137
https://doi.org/10.3171/2013.11.jns131137