Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sabhya, Rana"'
Publikováno v:
eLife, Vol 12 (2024)
Neurogenic bladder dysfunction causes urological complications and reduces the quality of life in persons with spinal cord injury (SCI). Glutamatergic signaling via AMPA receptors is fundamentally important to the neural circuits controlling bladder
Externí odkaz:
https://doaj.org/article/63d68a787b7c48feb1c69d96db625993
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Impaired diaphragm activation is common in many neuromuscular diseases. We hypothesized that expressing photoreceptors in diaphragm myofibers would enable light stimulation to evoke functional diaphragm activity, similar to endogenous bursts
Externí odkaz:
https://doaj.org/article/1e8ec7e8d0284e4a921773f98e8ee292
Autor:
Janak Gaire, Justin A. Varholick, Sabhya Rana, Michael D. Sunshine, Sylvain Doré, W. Brad Barbazuk, David D. Fuller, Malcolm Maden, Chelsey S. Simmons
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-6 (2021)
Abstract The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-r
Externí odkaz:
https://doaj.org/article/4306fc73e62c49328f78cf0387d70821
Publikováno v:
Journal of Applied Physiology. 134:1332-1340
Type S and FR motor units, comprising smaller phrenic motor neurons (PhMNs) are regularly activated to perform indefatigable ventilatory requirements. By contrast, type FF motor units, comprising larger PhMNs, are infrequently activated to perform ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43798ffe4e3bb8658d0c483996529a43
https://doi.org/10.1152/japplphysiol.00021.2023
https://doi.org/10.1152/japplphysiol.00021.2023
Autor:
Michele L. Singer, Sabhya Rana, Ethan S. Benevides, Brian E. Barral, Barry J. Byrne, David D. Fuller
Publikováno v:
Journal of Neurophysiology. 128:1133-1142
Pompe disease is a lysosomal storage disease resulting from absence or deficiency of acid α-glucosidase (GAA). Tongue-related disorders including dysarthria, dysphagia, and obstructive sleep apnea are common in Pompe disease. Our purpose was to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1067d35ec2f24da5c2b7ca723a2a9f0e
https://doi.org/10.1152/jn.00026.2022
https://doi.org/10.1152/jn.00026.2022
Publikováno v:
bioRxiv
Neurogenic bladder dysfunction causes urological complications and reduces the quality of life in persons with spinal cord injury (SCI). Glutamatergic signaling via AMPA receptors is fundamentally important to the neural circuits controlling bladder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dca0e3f2f5eea9a952ab9f414e8f0d2
https://europepmc.org/articles/PMC10245998/
https://europepmc.org/articles/PMC10245998/
Publikováno v:
Physiology. 38
Pompe disease is a monogenic neuromuscular disorder caused by a mutation in the gene encoding the lysosomal enzyme acid alpha-glucosidase. This leads to widespread glycogen accumulation, cardiorespiratory failure, and early mortality. There is clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14e2c621bc5cdb949a620022580cda6
https://doi.org/10.1152/physiol.2023.38.s1.5732423
https://doi.org/10.1152/physiol.2023.38.s1.5732423
Publikováno v:
Physiology. 38
Pompe disease is a neuromuscular disorder resulting from mutations in the gene for acid a-glucosidase (GAA) – an enzyme necessary to degrade lysosomal glycogen. Early-onset disease occurs in the absence of functional GAA, which leads to cardiorespi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62237d88559245c942d81557c30490cd
https://doi.org/10.1152/physiol.2023.38.s1.5734274
https://doi.org/10.1152/physiol.2023.38.s1.5734274
Autor:
Michele Singer, Ethan Benevides, Sabhya Rana, Robert Martinez, Brian Barral, Michael Sunshine, Barry Byrne, David Fuller
Publikováno v:
Physiology. 38
Contraction of the tongue muscles is needed for effective swallowing, speaking and breathing. Thus, inadequate tongue muscle activation can contribute to devastating conditions such as dysarthria, dysphagia, and obstructive sleep apnea. Existing trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42ef9d0b2935d7916b75fbb9bf48d77f
https://doi.org/10.1152/physiol.2023.38.s1.5726047
https://doi.org/10.1152/physiol.2023.38.s1.5726047
Publikováno v:
Physiology. 38
We recently described a panel of novel antibodies to epitopes on the neurofilament light chain (NF-L) which are hidden in healthy neurons and their processes but specifically exposed during neurodegeneration ( doi.org/10.1101/2022.08.27.504533 ). We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb8b7bffa283904c6ee1f4b3b4ae178
https://doi.org/10.1152/physiol.2023.38.s1.5732652
https://doi.org/10.1152/physiol.2023.38.s1.5732652