In Vivo DNA Re-replication Elicits Lethal Tissue Dysplasias

Autor: Alba de Martino, Sergio Muñoz, Sagrario Ortega, Sabela S Búa, Sara Rodriguez-Acebes, Diego Megías, Juan Méndez

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Cell Reports, Vol 19, Iss 5, Pp 928-938 (2017)

Mammalian DNA replication origins are "licensed" by the loading of DNA helicases, a reaction that is mediated by CDC6 and CDT1 proteins. After initiation of DNA synthesis, CDC6 and CDT1 are inhibited to prevent origin reactivation and DNA overreplica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce69531389e981b88fda0b9fad48334c
http://hdl.handle.net/20.500.12105/7230

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Hemodynamic Management guided by the Hypotension Prediction Index in Abdominal Surgery: A Multicenter Randomized Clinical Trial.

Autor: Ripollés-Melchor J; Infanta Leonor University Hospital, Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain.; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain., Tomé-Roca JL; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; Virgen de las Nieves University Hospital, Granada, Spain., Zorrilla-Vaca A; Brigham and Women's Hospital, Boston, USA., Aldecoa C; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; Río Hortega University Hospital, Valladolid, Spain., Colomina MJ; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; Bellvitge University Hospital, Barcelona, Spain.; Barcelona University, Barcelona, Spain., Bassas-Parga E; Moisès Broggi University Hospital, Sant Joan Despí, Spain., Lorente JV; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; Juan Ramón Jiménez University Hospital, Huelva, Spain., Ruiz-Escobar A; Infanta Leonor University Hospital, Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain., Carrasco-Sánchez L; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; Althaia Xarxa Assistencial Universitària de Manresa, Manresa, Spain.; Doctoral Program in Medicine and Biomedical Sciences, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; Institute of Research and Innovation in Life and Health Sciences in Central Catalonia (IRIS-CC), Vic, Spain., Sadurni-Sarda M; Del Mar University Hospital, Barcelona, Spain., Rivas E; Barcelona Clinic Hospital, Barcelona, Spain., Puig J; University General Hospital Consortium of Valencia, Valencia, Spain.; Valencia University, Valencia, Spain., Agudelo-Montoya E; University Hospital Complex of Badajoz, Badajoz, Spain., Del Rio-Fernández S; University Hospital Complex of Santiago, Santiago de Compostela, Spain., García-López D; Marqués de Valdecilla University Hospital, Santander, Spain., Adell-Pérez AB; Donostia University Hospital, San Sebastian, Spain., Guillen A; University Clinical Hospital of Valencia, Valencia, Spain., Venturoli-Ojeda R; Jerez de la Frontera University Hospital, Jerez de la Frontera, Spain., Fernández-Torres B; Virgen de la Macarena University Hospital, Sevilla, Spain., Abad-Motos A; Donostia University Hospital, San Sebastian, Spain., Mojarro I; Juan Ramón Jiménez University Hospital, Huelva, Spain., Garrido-Calmaestra JL; Reina Sofía University Hospital, Córdoba, Spain., Fernanz-Antón J; Moisès Broggi University Hospital, Sant Joan Despí, Spain., Pedregosa-Sanz A; Igualada University Hospital, Igualada, Spain., Cueva-Castro L; Sant Pau University Hospital, Barcelona, Spain., Echevarria-Correas MA; Basurto University Hospital, Bilbao, Spain., Mallol M; Barcelona University, Barcelona, Spain., Olvera-García MM; San Cecilio University Hospital, Granada, Spain., Navarro-Pérez R; Clínico San Carlos University Hospital, Madrid, Spain., Fernández-Valdés-Bango P; Infanta Leonor University Hospital, Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain., García-Fernández J; Puerta de Hierro University Hospital, Majadahonda, Spain.; Autonomous University of Madrid, Madrid, Spain., Espinosa ÁV; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; King Salman Specialist Hospital, Hail, Kingdom of Saudi Arabia., Abu Khudair H; King Hussein Cancer Center, Amman, Jordan., Becerra-Bolaños Á; Doctor Negrín University Hospital of Gran Canaria, Gran Canaria, Spain., Díez-Remesal Y; Ramón y Cajal University Hospital, Madrid, Spain., Fuentes-Pradera MA; Virgen del Rocío University Hospital, Sevilla, Spain., Valbuena-Bueno MA; Polytechnic University of Madrid, Madrid, Spain.; Parc Taulí Research and Innovation Institute (I3PT), Sabadell, Spain., Quintana-Villamandos B; Universidad Complutense de Madrid, Madrid, Spain.; Gregorio Marañón University Hospital, Madrid, Spain., Llorca-García J; Althaia Xarxa Assistencial Universitària de Manresa, Manresa, Spain., Fernández-López I; Gregorio Marañón University Hospital, Madrid, Spain., Ocón-Moreno Á; Virgen de las Nieves University Hospital, Granada, Spain., Martín-Infantes SL; Virgen de las Nieves University Hospital, Granada, Spain., Valiente-Lourtau JM; Virgen de la Macarena University Hospital, Sevilla, Spain., Amelburu-Egoscozabal M; Donostia University Hospital, San Sebastian, Spain., Rivera-Ramos H; Del Mar University Hospital, Barcelona, Spain., Abad-Gurumeta A; Infanta Leonor University Hospital, Madrid, Spain.; Universidad Complutense de Madrid, Madrid, Spain., Monge-García MI; Fluid Therapy and Hemodynamic Monitoring, Spanish Society of Anesthesia and Critical Care (SEDAR), Madrid, Spain.; Jerez de la Frontera University Hospital, Jerez de la Frontera, Spain.

Publikováno v: Anesthesiology [Anesthesiology] 2025 Jan 02. Date of Electronic Publication: 2025 Jan 02.

Adenoma detection rate and tolerability of 2 ultra-low-volume bowel preparations in screening: a noninferiority randomized controlled trial.

Autor: Serradesanferm A; Department of Preventive Medicine and Epidemiology, Hospital Clinic of Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; ISGlobal, Barcelona, Spain., Torá-Rocamora I; Department of Preventive Medicine and Epidemiology, Hospital Clinic of Barcelona, Barcelona, Spain; ISGlobal, Barcelona, Spain; University of Barcelona, Barcelona, Spain., Pozo À; Department of Preventive Medicine and Epidemiology, Hospital Clinic of Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; ISGlobal, Barcelona, Spain., Ocaña T; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain., Diaz M; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Moreira R; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain., Rivero-Sánchez L; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Ortiz O; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Carballal S; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Moreira L; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Vaquero EC; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Ordás I; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Bayarri C; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain., Daca-Alvarez M; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Torres S; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain., Grau J; Department of Preventive Medicine and Epidemiology, Hospital Clinic of Barcelona, Barcelona, Spain; ISGlobal, Barcelona, Spain; University of Barcelona, Barcelona, Spain., Balaguer F; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Castells A; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Pellisé M; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain; University of Barcelona, Barcelona, Spain; Department of Gastroenterology, Hospital Clinic of Barcelona, Barcelona, Spain; Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Publikováno v: Gastrointestinal endoscopy [Gastrointest Endosc] 2025 Jan; Vol. 101 (1), pp. 158-167.e7. Date of Electronic Publication: 2024 Jul 26.

The effects of isolated game elements on adherence rates in food response inhibition training.

Autor: MacLellan A; Department of Psychology, University of Bath, Bath BA2 7AY, UK., Pennington CR; School of Psychology, Aston University, Birmingham B4 7ET, UK., Lawrence N; Department of Psychology, University of Exeter, Exeter EX4 4QG, UK., Westwood SJ; Department of Psychology, Kings College London, London WC2R 2LS, UK., Jones A; School of Psychology, Liverpool John Moores University, Liverpool L2 2QP, UK., Slegrova A; Department of Psychology, University of Bath, Bath BA2 7AY, UK., Sung B; Department of Psychology, University of Bath, Bath BA2 7AY, UK., Parker L; Department of Psychology, University of Bath, Bath BA2 7AY, UK., Relph L; Department of Psychology, University of Bath, Bath BA2 7AY, UK., Miranda JO; Department of Psychology, University of Bath, Bath BA2 7AY, UK., Shakeel M; School of Psychology, Aston University, Birmingham B4 7ET, UK., Mouka E; School of Psychology, Aston University, Birmingham B4 7ET, UK., Lovejoy C; Department of Psychology, University of Exeter, Exeter EX4 4QG, UK., Chung C; Department of Psychology, University of Exeter, Exeter EX4 4QG, UK., Lash S; Department of Psychology, University of Exeter, Exeter EX4 4QG, UK., Suhail Y; Department of Psychology, Kings College London, London WC2R 2LS, UK., Nag M; Department of Psychology, Kings College London, London WC2R 2LS, UK., Button KS; Department of Psychology, University of Bath, Bath BA2 7AY, UK.

Publikováno v: Royal Society open science [R Soc Open Sci] 2024 Dec 11; Vol. 11 (12), pp. 241657. Date of Electronic Publication: 2024 Dec 11 (Print Publication: 2024).