Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Sabato, Fusco"'
Autor:
Rocco Mottareale, Crescenzo Frascogna, Giuseppe La Verde, Cecilia Arrichiello, Paolo Muto, Paolo A. Netti, Sabato Fusco, Valeria Panzetta, Mariagabriella Pugliese
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The stiffness of the extracellular matrix plays a crucial role in cell motility and spreading, influencing cell morphology through cytoskeleton organization and transmembrane proteins’ expression. In this context, mechanical characterization of bot
Externí odkaz:
https://doaj.org/article/1b112e7e25814129a571251ad49e908e
Autor:
Angelica Perna, Noemi Venditti, Francesco Merolla, Sabato Fusco, Germano Guerra, Stefano Zoroddu, Antonio De Luca, Luigi Bagella
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9688 (2024)
The placenta is crucial to fetal development and performs vital functions such as nutrient exchange, waste removal and hormone regulation. Abnormal placental development can lead to conditions such as fetal growth restriction, pre-eclampsia and still
Externí odkaz:
https://doaj.org/article/7caf895d164d47528f75c6c46337af5b
Autor:
Alessandro Poli, Fabrizio A. Pennacchio, Andrea Ghisleni, Mariagrazia di Gennaro, Margaux Lecacheur, Paulina Nastały, Michele Crestani, Francesca M. Pramotton, Fabio Iannelli, Galina Beznusenko, Alexander A. Mironov, Valeria Panzetta, Sabato Fusco, Bhavwanti Sheth, Dimos Poulikakos, Aldo Ferrari, Nils Gauthier, Paolo A. Netti, Nullin Divecha, Paolo Maiuri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
PIP4Ks are phosphoinositide kinases often dysregulated in cancer. Here Poli and colleagues find that PIP4K2B is downregulated on soft substrates, and its depletion leads to altered nuclear mechanical properties and defects in cell spreading and motil
Externí odkaz:
https://doaj.org/article/4d9e3d61d6c2464f8d96e71e834db4ef
Autor:
Rosa Carotenuto, Margherita Tussellino, Sabato Fusco, Giovanna Benvenuto, Fabio Formiggini, Bice Avallone, Chiara Maria Motta, Chiara Fogliano, Paolo Antonio Netti
Publikováno v:
Nanomaterials, Vol 13, Iss 17, p 2488 (2023)
Exposure to metal nanoparticles is potentially harmful, particularly when occurring during embryogenesis. In this study, we tested the effects of commercial AuNPs and AgNPs, widely used in many fields for their features, on the early development of X
Externí odkaz:
https://doaj.org/article/530902d95aa6428b80e59ae89fc56fac
Autor:
Giuseppe La Verde, Valeria Artiola, Mariagabriella Pugliese, Marco La Commara, Cecilia Arrichiello, Paolo Muto, Paolo A. Netti, Sabato Fusco, Valeria Panzetta
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The microenvironment of breast cancer actively participates in tumorigenesis and cancer progression. The changes observed in the architecture of the extracellular matrix initiate an oncogene-mediated cell reprogramming, that leads to a massive trigge
Externí odkaz:
https://doaj.org/article/8dd08e3c91f44062ac1ec67340ec7866
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Malignant pleural mesothelioma is a relatively rare, but devastating tumor, because of the difficulties in providing early diagnosis and effective treatments with conventional chemo- and radiotherapies. Patients usually present pleural effusions that
Externí odkaz:
https://doaj.org/article/b7f35a301cf24001bd72e0fbc1c7d9a2
Characterization of Hyaluronic Acid-Coated PLGA Nanoparticles by Surface-Enhanced Raman Spectroscopy
Autor:
Giuseppe La Verde, Antonio Sasso, Giulia Rusciano, Angela Capaccio, Sabato Fusco, Laura Mayol, Marco Biondi, Teresa Silvestri, Paolo A. Netti, Marco La Commara, Valeria Panzetta, Mariagabriella Pugliese
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 601 (2022)
Nanoparticles (NPs) coated with hyaluronic acid (HA) seem to be increasingly promising for targeted therapy due to HA chemical versatility, which allows them to bind drugs of different natures, and their affinity with the transmembrane receptor CD-44
Externí odkaz:
https://doaj.org/article/094fcbf2cd2d4fc09a5f08e63f1c0bc8
Autor:
Concetta Di Natale, Elena Lagreca, Valeria Panzetta, Marianna Gallo, Francesca Passannanti, Michele Vitale, Sabato Fusco, Raffaele Vecchione, Roberto Nigro, Paolo Netti
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The intestinal microbiota is a real ecosystem composed of several bacterial species and a very huge amount of strains that through their metabolic activities play a crucial role in the development and performance of the immune system and other functi
Externí odkaz:
https://doaj.org/article/0a596af6f329461b9e9549cce283c193
Autor:
Valeria Panzetta, Giuseppe La Verde, Mariagabriella Pugliese, Cecilia Arrichiello, Paolo Muto, Marco La Commara, Vittoria D'Avino, Paolo A. Netti, Sabato Fusco
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
A large body of literature has demonstrated that the mechanical properties of microenvironment have a key role in regulating cancer cell adhesion, motility, and invasion. In this work, we have introduced two additional parameters, named cell trajecto
Externí odkaz:
https://doaj.org/article/3e5e5a1cef2343b2b9500f3b603473ee
Autor:
Giuseppe La Verde, Valeria Artiola, Valeria Panzetta, Mariagabriella Pugliese, Paolo A. Netti, Sabato Fusco
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1102 (2021)
The cytoskeleton is involved in several biological processes, including adhesion, motility, and intracellular transport. Alterations in the cytoskeletal components (actin filaments, intermediate filaments, and microtubules) are strictly correlated to
Externí odkaz:
https://doaj.org/article/04ac371310bb439a9d8ac6a006830ed4