Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sabari Dutta"'
Autor:
Subhash Padhye, Atanu Barik, Hong-Yu Zhang, K. Indira Priyadarsini, Ramakant Mahadeo Kadam, Amit Kunwar, Ashis K. Satpati, Liang Shen, Sabari Dutta, B. Mishra
Publikováno v:
European Journal of Medicinal Chemistry. 42:431-439
Two stoichiometrically different copper(II) complexes of curcumin (stoichiometry, 1:1 and 1:2 for copper:curcumin), were examined for their superoxide dismutase (SOD) activity, free radical-scavenging ability and antioxidant potential. Both the compl
Publikováno v:
Inorganica Chimica Acta. 358:3617-3624
The superoxide dismutase (SOD) mimicking potential of three pyridazolato-bridged copper complexes has been investigated by NBT assay. The lowest IC 50 value observed for the SOD activity (3.90 × 10 −7 M) for [Cu 2 {bis(3,6 pyrazol-1-yl)pyridazine}
Publikováno v:
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 35:3-10
Modulation of the intrinsic oxidative stress in invasive metastatic cancer cells using two superoxide dismutase mimicking conjugates of catecholamine Schiff base ligand 3‐[(2′–(2″ pyridylethyl)iminoethyl] benzene‐1,2 diol] (1) results in su
Publikováno v:
Inorganic Chemistry Communications. 7:1071-1074
SOD activity of the diaryl substituted heterocyclic COX-2 inhibitor, viz. oxaprozin (2), is synergistically enhanced upon copper conjugation compared to analogous copper compounds of established COX-1 inhibitors like aspirin (1) and ibuprofen (3). A
Autor:
Annie K. Powell, Sabari Dutta, CJ Newton, Shreelekha Padhye, Subhash Padhye, Christopher E. Anson, Zahra Afrasiabi, Ekk Sinn
Publikováno v:
Journal of Inorganic Biochemistry. 95:306-314
The thiosemicarbazone derivative of 9,10-phenanthrenequinone, 1, and its metal complexes were synthesized. The X-ray crystal structure for 1 confirms the presence of the E tautomeric arrangement in this compound. Its copper complex shows 1:1 stoichio
Publikováno v:
Inorganica Chimica Acta. 318:207-211
The copper(II) complexes of the Schiff base salicylaldehyde semicarbazone (SALSC) have been prepared and structurally characterized. The compound possesses a distorted square planar geometry where the metal atom lies slightly below the ligand donor a
Publikováno v:
Metal-Based Drugs
Antioxidant properties of three Curcumin derivatives in which the 1,3-diketone system is appended with nitrogen and sulfur donors and their copper conjugates are examined for the first time. Metal conjugation seems to offer distinct advantages in rad
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(11)
A new semicarbazone derivative of curcumin (CRSC) was synthesized and examined for its antioxidant, antiproliferative, and antiradical activity and compared with those of curcumin (CR). The antioxidant activity was tested by their ability to inhibit
Publikováno v:
Analytical biochemistry. 294(2)
A disposable fiber-optic sensor based on the immobilized tyrosinase enzyme in a composite biopolymer and its application for the detection of 3,4-dihydroxyphenyalanine ( l -dopa) and its analog are described. The enzymatic oxidation product of l -dop
Publikováno v:
Biosensorsbioelectronics. 16(4-5)
A method is described for the incorporation of tiron as a substrate for tyrosinase enzyme into a polypyrrole film deposited on indium titanium oxide (ITO) glass. The presence of tiron in the polypyrrole film is verified by cyclic voltammetry (CV). Th