Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sabah Bharde"'
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
An estimated 10%–50% of patients undergoing a surgical intervention will develop persistent postsurgical pain (PPP) lasting more than 3 months despite adequate acute pain management and the availability of minimally invasive procedures. The link be
Externí odkaz:
https://doaj.org/article/5ecd759f94a44351b2fb8c3e36bbe90d
Autor:
Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez‐Fallas, Anne‐Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract We showed that the chemokine receptor C‐X‐C Motif Chemokine Receptor 2 (CXCR2) is essential for cartilage homeostasis. Here, we reveal that the CXCR2 ligand granulocyte chemotactic protein 2 (GCP‐2) was expressed, during embryonic deve
Externí odkaz:
https://doaj.org/article/c6ccca64be374eba90196cda5f86dbe7
Autor:
João de Sousa Valente, Khadija M. Alawi, Patrik Keringer, Sabah Bharde, Faseeha Ayaz, Nurjahan Saleque, Xenia Kodji, Dibesh Thapa, Fulye Argunhan, Susan D. Brain
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 4, Pp 100119- (2020)
Introduction: Osteo-arthritis (OA) involves joint degradation and usually pain; with mechanisms poorly understood and few treatment options. There is evidence that the transient receptor potential canonical 5 (TRPC5) mRNA expression is reduced in OA
Externí odkaz:
https://doaj.org/article/2c54f1ea129e4e75adabb9d90137596c
Publikováno v:
Curr Opin Support Palliat Care
PURPOSE OF REVIEW Osteoarthritis is a degenerative joint disease that features pain as a hallmark symptom. This review summarises progress and obstacles in our understanding of pain mechanisms in arthritis. RECENT FINDINGS Pain phenotypes in osteoart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6283c8dd7fd6f3ba6bf2bd28cacf9767
https://europepmc.org/articles/PMC7610722/
https://europepmc.org/articles/PMC7610722/
Autor:
Joao de Sousa Valente, Susan D. Brain, Khadija M. Alawi, Sabah Bharde, Ali A Zarban, Xenia Kodji, Brentton Barrett, István Nagy, Fulye Argunhan, Dibesh Thapa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6380, p 6380 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences
Volume 22
Issue 12
Recently, we found that the deletion of TRPC5 leads to increased inflammation and pain-related behaviour in two animal models of arthritis. (-)-Englerin A (EA), an extract from the East African plant Phyllanthus engleri has been identified as a TRPC4