Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Saba Selvi"'
Autor:
Seref Gul, Yasemin Kubra Akyel, Zeynep Melis Gul, Safak Isin, Onur Ozcan, Tuba Korkmaz, Saba Selvi, Ibrahim Danis, Ozgecan Savlug Ipek, Fatih Aygenli, Ali Cihan Taskin, Büşra Aytül Akarlar, Nurhan Ozlu, Nuri Ozturk, Narin Ozturk, Durişehvar Özer Ünal, Mustafa Guzel, Metin Turkay, Alper Okyar, Ibrahim Halil Kavakli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Cryptochromes are transcriptional regulators of the circadian clock in mammals, and genetic loss of cryptochromes reduces p53-associated cancer risk in mice. Here the authors report the discovery of small molecule M47, which destabilizes cryptochrome
Externí odkaz:
https://doaj.org/article/74ebf0d9b13b4f24b201b187236a7cc6
Autor:
Huseyin Gul, Saba Selvi, Fatma Yilmaz, Gozde Ozcelik, Senanur Olfaz‐Aslan, Seyma Yazan, Busra Tiryaki, Seref Gul, Ali Yurtseven, Ibrahim Halil Kavakli, Nurhan Ozlu, Nuri Ozturk
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 90:1315-1330
Circadian rhythms are a series of endogenous autonomous 24-h oscillations generated by the circadian clock. At the molecular level, the circadian clock is based on a transcription-translation feedback loop, in which BMAL1 and CLOCK transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cab20725e73fc691b4be6717fb3a6c5
https://doi.org/10.1002/prot.26314
https://doi.org/10.1002/prot.26314
Transcriptome analysis of the circadian clock gene BMAL1 deletion with opposite carcinogenic effects
Autor:
Nuri Ozturk, Seref Gul, Onur Ozcan, Ibrahim Halil Kavakli, Hande Morgil, Saba Selvi, Fatih Aygenli, Handan Emisoglu-Kulahli
Publikováno v:
Functional & Integrative Genomics. 21:1-16
We have previously reported that the deletion of BMAL1 gene has opposite effects in respect to its contribution to the pathways that are effective in the multistage carcinogenesis process. BMAL1 deletion sensitized nearly normal breast epithelial (MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6bb2453de9f190e77da73b58d0797cc
https://doi.org/10.1007/s10142-020-00757-6
https://doi.org/10.1007/s10142-020-00757-6
Autor:
Saba Selvi, Yasemin Kubra Akyel, Mustafa Guzel, Fatih Aygenli, Nuri Ozturk, Ali Cihan Taskin, Safak Isin, Durisehvar Ozer Unal, Ibrahim Danis, Metin Turkay, Ozgecan Savlug Ipek, Seref Gul, Zeynep Melis Gul, Narin Ozturk, Alper Okyar, Tuba Korkmaz, Ibrahim Halil Kavakli
Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous level of the CRY1 in mammals will affect circadian rhythm and the relation of such a decrease with apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03a2d1288d0a764da3ba1cf2f8bf2a8d
https://doi.org/10.1101/2021.07.21.453206
https://doi.org/10.1101/2021.07.21.453206
Autor:
Seref Gul, Yasemin Kubra Akyel, Zeynep Melis Gul, Safak Isin, Onur Ozcan, Tuba Korkmaz, Saba Selvi, Ibrahim Danis, Ozgecan Savlug Ipek, Fatih Aygenli, Ali Cihan Taskin, Büşra Aytül Akarlar, Nurhan Ozlu, Nuri Ozturk, Narin Ozturk, Durişehvar Özer Ünal, Mustafa Guzel, Metin Turkay, Alper Okyar, Ibrahim Halil Kavakli
Publikováno v:
Nature Communications
Cryptochromes are negative transcriptional regulators of the circadian clock in mammals. It is not clear how reducing the level of endogenous CRY1 in mammals will affect circadian rhythm and the relation of such a decrease with apoptosis. Here, we di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a15ca742cbd52392b0eafb83cb5d0e
https://pubmed.ncbi.nlm.nih.gov/36347873
https://pubmed.ncbi.nlm.nih.gov/36347873