Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Saba Haq"'
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102194- (2021)
Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. A
Externí odkaz:
https://doaj.org/article/9e86097e17c44e0584804c8b9f893765
Autor:
Saba Haq, Suresh Ramakrishna
Publikováno v:
Open Biology, Vol 7, Iss 6 (2017)
Deubiquitylating enzymes (DUBs) reverse the ubiquitylation of target proteins, thereby regulating diverse cellular functions. In contrast to the plethora of research being conducted on the ability of DUBs to counter the degradation of cellular protei
Externí odkaz:
https://doaj.org/article/27d11c265fca40e599304446a7eb6f55
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 10, Pp 12556-12572 (2012)
Cancer epidemiology and prevention is one of the most well studied fields today. The more we can understand about the incidence and pathogenesis of this disease, the better we will be able to prevent it. Effective prevention strategies can decrease t
Externí odkaz:
https://doaj.org/article/75298cb4dba5444ca4281ef04b93d277
Autor:
Suresh Ramakrishna, Arun Pandian Chandrasekaran, Hyongbum Kim, Soumyadip Das, Jaesang Kim, Kye Seong Kim, Jaewon Kim, Bharathi Suresh, Sanghyuk Lee, Saba Haq, Jae Hyeok Kang, Su Jae Lee
Publikováno v:
Cell Death Differ
Conventional screening methods for deubiquitinating enzymes (DUBs) have important limitations. A loss-of-function study based on the knockout of DUB genes in mammalian cells can provide an excellent model for exploring DUB function. Here, we used CRI
Publikováno v:
Redox Biology, Vol 48, Iss, Pp 102194-(2021)
Redox Biology
Redox Biology
Reactive oxygen species (ROS) act as a double-edged sword in cancer, where low levels of ROS are beneficial but excessive accumulation leads to cancer progression. Elevated levels of ROS in cancer are counteracted by the antioxidant defense system. A
Publikováno v:
Cureus
Neurosyphilis is a disease caused by systemic infection with Treponema pallidum, which infiltrates the central nervous system and preganglionic dorsal roots. This process presents as neurological deficits and can occur any time during the infection c
Autor:
Janardhan Keshav Karapurkar, Bharathi Suresh, Saba Haq, Vijai Singh, Yun Soo Bae, Kye Seong Kim, Jung Ki Jo, Suresh Ramakrishna, Neha Sarodaya
Publikováno v:
Cancer letters. 525
The NADPH oxidase (Nox) family of enzymes is solely dedicated in the generation of reactive oxygen species (ROS). ROS generated by Nox are involved in multiple signaling cascades and a myriad of pathophysiological conditions including cancer. As such
Autor:
Kamini Kaushal, Eun-Jung Kim, Apoorvi Tyagi, Janardhan Keshav Karapurkar, Saba Haq, Han-Sung Jung, Kye-Seong Kim, Suresh Ramakrishna
Publikováno v:
Cell death and differentiation. 29(9)
Proteins expressed by the paired box gene 9 (PAX9) and Msh Homeobox 1 (MSX1) are intimately involved in tooth development (odontogenesis). The regulation of PAX9 and MSX1 protein turnover by deubiquitinating enzymes (DUBs) plausibly maintain the requ
Autor:
Saba Haq, Suresh Ramakrishna, Soumyadip Das, Arun Pandian Chandrasekaran, Kye Seong Kim, Seok Ho Hong, Dong Ho Kim
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:599-610
RNA-binding protein LIN28A is often highly expressed in human malignant tumors and is involved in tumor metastasis and poor prognosis. Knowledge about post-translational regulatory mechanisms governing LIN28A protein stability and function is scarce.