Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Saarah F G, Davids"'
Autor:
Dipuo D. Motshwari, Cindy George, Don M. Matshazi, Cecil J. Weale, Saarah F. G. Davids, Annalise E. Zemlin, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The burden of chronic kidney disease (CKD) in Africa remains poorly characterized, due partly to the lack of appropriate diagnostic strategies. Although in recent years the diagnostic and prognostic utility of microRNAs (miRNAs) have gained
Externí odkaz:
https://doaj.org/article/2f09134b67304a3a8a00568bb1362cb5
Autor:
Yvonne Prince, Glenda M. Davison, Saarah F. G. Davids, Rajiv T. Erasmus, Andre P. Kengne, Lisa M. Graham, Shanel Raghubeer, Tandi E. Matsha
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 3 (2022)
The oral microbiota plays a crucial role in both systemic inflammation and metabolic syndrome (MetS), which is characterised by low-grade inflammation. Studies have analysed the gut microbiota using stool specimens from subjects with MetS; however, t
Externí odkaz:
https://doaj.org/article/815c53bf8b494b8ab8c9fd30a2b4b1aa
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Aim: The influence of disease duration and anti-diabetic treatment on epigenetic processes has been described, with limited focus on interactions with microRNAs (miRNAs). miRNAs have been found to play key roles in the regulation of pathways associat
Externí odkaz:
https://doaj.org/article/9379b3e8f54f4bf597f7cfb184cd8158
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
MicroRNAs are non-coding, post-transcriptional regulators of gene expression and their dysregulation has been associated with development of various diseases, including hypertension. Consequently, understanding their role in the pathogenesis and prog
Externí odkaz:
https://doaj.org/article/2dfb007e921b4233948dca301a242b23
Autor:
Don M. Matshazi, Cecil J. Weale, Rajiv T. Erasmus, Andre P. Kengne, Saarah F. G. Davids, Shanel Raghubeer, Stanton Hector, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Hypertension has a complex pathogenesis and symptoms appear in advanced disease. Dysregulation of gene expression regulatory factors like microRNAs has been reported in disease development. Identifying biomarkers which could help understand the patho
Externí odkaz:
https://doaj.org/article/f36ace27c13b41ac87f18b507fab83ac
Autor:
Dipuo D. Motshwari, Cindy George, Don M. Matshazi, Cecil J. Weale, Saarah F. G. Davids, Rajiv T. Erasmus, Andre P. Kengne, Tandi E. Matsha
Publikováno v:
Applied Sciences, Vol 11, Iss 16, p 7674 (2021)
The asymptomatic nature of and lack of effective early-stage diagnostic tools in CKD, predisposes individuals to the risk of end-stage CKD and related complications. Whole blood microRNAs (miRNAs) have the potential for CKD risk screening. We evaluat
Externí odkaz:
https://doaj.org/article/acbf995444164b9883246d3701dd017a
Autor:
Cecil J. Weale, Don M. Matshazi, Saarah F. G. Davids, Shanel Raghubeer, Rajiv T. Erasmus, Andre P. Kengne, Glenda M. Davison, Tandi E. Matsha
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 949 (2021)
This cross-sectional study investigated the association of miR-1299, -126-3p and -30e-3p with and their diagnostic capability for dysglycaemia in 1273 (men, n = 345) South Africans, aged >20 years. Glycaemic status was assessed by oral glucose tolera
Externí odkaz:
https://doaj.org/article/0334ae5876444e069f74c91a88b55d81
Autor:
Tandi E. Matsha, Cecil J. Weale, Rajiv T Erasmus, Glenda M. Davison, Don M Matshazi, Shanel Raghubeer, Andre Pascal Kengne, Saarah F G Davids
Publikováno v:
Molecular Biology Reports
MicroRNAs are important in development of disease, and description of novel microRNAs adds to the pool of microRNAs that can be targeted for diagnostic and therapeutic purposes in disease. Herein, we aimed to describe novel microRNAs in a normotensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdfc52afe6f1d25c25cfbd9222db5c2
https://doi.org/10.1007/s11033-021-06304-1
https://doi.org/10.1007/s11033-021-06304-1
Autor:
Tandi E. Matsha, Shanel Raghubeer, Gloudina M. Hon, Saarah F G Davids, Abegail M Tshivhase, Rajiv T Erasmus, Lise Bjørkhaug
Publikováno v:
The Application of Clinical Genetics. 13:209-219
Background and aim Maturity-onset diabetes of the young (MODY) is the result of single gene variants. To date, fourteen different MODY subtypes have been described. Variants in genes coding for glucokinase (GCK, MODY2) and hepatic nuclear factor 1 al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6c85f93c7df5d9e08435e7d404a8955
https://doi.org/10.2147/tacg.s281872
https://doi.org/10.2147/tacg.s281872
Autor:
Glenda M. Davison, Cecil J. Weale, Rajiv T Erasmus, Andre Pascal Kengne, Saarah F G Davids, Shanel Raghubeer, Don M Matshazi, Tandi E. Matsha
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Cecil Jack Weale,1 Don M Matshazi,1 Saarah FG Davids,1 Shanel Raghubeer,1 Rajiv T Erasmus,2 Andre Pascal Kengne,3,4 Glenda Mary Davison,1 Tandi E Matsha1 1SAMRC/CPUT/Cardiometabolic Health Research Unit, Department of Biomedical Sciences, Faculty of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e41dc335f96ccf5fcbdeca89ebef0fe
http://europepmc.org/articles/PMC7762450
http://europepmc.org/articles/PMC7762450