Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Saami K. Yazdani"'
Autor:
Danyi Chen, Colin Krinsky, Mollie Phillips, Catherine Allred, Ava Khan, Linda B. Liu, Uwe Christians, Saami K. Yazdani
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 2, Pp n/a-n/a (2024)
Abstract Currently, there are no ex vivo systems that can model the motion of peripheral arteries and allow for the evaluation of pharmacokinetics (PK) of endovascular devices. The objective of this study was to develop a novel peripheral simulating
Externí odkaz:
https://doaj.org/article/e38fc6be8efa41deb1641b47394e1937
Autor:
Beilei Lei, Linda B. Liu, Lauren Stokes, Paloma H. Giangrande, Francis J. Miller, Jr., Saami K. Yazdani
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102023- (2023)
The local delivery of antiproliferative agents to inhibit neointimal growth is not specific to vascular smooth muscle cells (VSMC) and delays reendothelialization and vascular healing. This investigation was intended to evaluate the effect of luminal
Externí odkaz:
https://doaj.org/article/45a81757d7534d55ac6af4b27abbb0b3
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionSirolimus is currently being explored as an alternative drug to paclitaxel for the treatment of peripheral artery disease (PAD). To date, sirolimus has only been used as drug coatings for stents and balloons and no studies have yet demons
Externí odkaz:
https://doaj.org/article/1b42b556d5fc4059815583aae0041a59
Autor:
Saami K. Yazdani, Beilei Lei, Claire V. Cawthon, Kathryn Cooper, Clifton Huett, Paloma H. Giangrande, Francis J. Miller, Jr.
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 577-583 (2022)
Anti-proliferative agents have been the primary therapeutic drug of choice to inhibit restenosis after endovascular treatment. However, recent safety and efficacy concerns for patients who underwent peripheral artery disease revascularization have de
Externí odkaz:
https://doaj.org/article/f60ad065679042edbbf850287c0647ad
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100170- (2023)
Externí odkaz:
https://doaj.org/article/ea979cba85384a7f93a375dbb74aacb0
Autor:
Marzieh K. Atigh, Emily Goel, Megan Erwin, Ricky Greer, Jacques Ohayon, Roderic I. Pettigrew, Saami K. Yazdani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Perfusion catheters have recently emerged as a novel approach to deliver liquid anti-proliferative agents into flow obstructed arterial segments. The purpose of this study was to determine the impact of luminal delivery pressure on liquid dr
Externí odkaz:
https://doaj.org/article/4dc75708f326434e88b03657883d5e7b
Autor:
Estefanny Villar-Matamoros BS, Lauren Stokes BS, Alyssa Lloret BS, Meagan Todd BS, Bryan W. Tillman MD, PhD, Saami K. Yazdani PhD
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics, Vol 27 (2022)
Objective: The purpose of this study was to determine the impact of varying inflation parameters on paclitaxel delivery and retention using a commercially available DCB. Background: Drug-coated balloons (DCB) have become the standard treatment for pe
Externí odkaz:
https://doaj.org/article/5879be0faf874232904b83cbd261a686
Autor:
Ofonime Udofot, Li-Hsien Lin, William H. Thiel, Megan Erwin, Emily Turner, Francis J. Miller, Jr., Paloma H. Giangrande, Saami K. Yazdani
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 360-366 (2019)
Current strategies to prevent restenosis following endovascular treatment include the local delivery of anti-proliferative agents to inhibit vascular smooth muscle cell (VSMC) proliferation and migration. These agents, not specific to VSMCs, are depo
Externí odkaz:
https://doaj.org/article/438818c7d6aa4813983b2dfef19ba4f9
Autor:
Kathryn Cooper, Claire V. Cawthon, Emily Goel, Marzieh Atigh, Uwe Christians, Saami K. Yazdani
Publikováno v:
Frontiers in Medical Technology, Vol 3 (2021)
Purpose: The goal of this study was to develop an ex vivo system capable of rapidly evaluating arterial drug levels in living, isolated porcine carotid arteries.Methods: A vascular bioreactor system was developed that housed a native porcine carotid
Externí odkaz:
https://doaj.org/article/3ed2fbbba22e48569e7d864e59d60e2e
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 111:538-550
Acellular vascular scaffolds with capture molecules have shown great promise in recruiting circulating endothelial colony forming cells (ECFCs) to promote in vivo endothelialization. A microenvironment conducive to cell spreading and differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9458de856cfacd6094721b26b1b30770
https://doi.org/10.1002/jbm.b.35170
https://doi.org/10.1002/jbm.b.35170