Evaluation of Solubility, Dissolution Rate, and Oral Bioavailability of β-Cyclodextrin and Hydroxypropyl β-Cyclodextrin as Inclusion Complexes of the Tyrosine Kinase Inhibitor, Alectinib.

Autor: Majeed BJM; Faculty of Pharmacy, Pharmacological and Diagnostic Research Center (PDRC), Al-Ahliyya Amman University, Amman 19328, Jordan., Saadallah MA; Faculty of Pharmacy, Pharmacological and Diagnostic Research Center (PDRC), Al-Ahliyya Amman University, Amman 19328, Jordan., Al-Ani IH; Faculty of Pharmacy, Pharmacological and Diagnostic Research Center (PDRC), Al-Ahliyya Amman University, Amman 19328, Jordan., El-Tanani MK; Faculty of Pharmacy, Pharmacological and Diagnostic Research Center (PDRC), Al-Ahliyya Amman University, Amman 19328, Jordan.; College of Pharmacy, RAK Medical and Health Sciences University, Ras Al-Khaimah P.O. Box 12973, United Arab Emirates., Al Azzam KM; Department of Chemistry, Faculty of Science, The University of Jordan, Amman 11942, Jordan., Abdallah HH; Chemistry Department, College of Education, Salahaddin University, Erbil 44002, Iraq., Al-Hajji F; Faculty of Pharmacy, Applied Science University, Amman 11937, Jordan.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Jun 05; Vol. 17 (6). Date of Electronic Publication: 2024 Jun 05.