Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Saad Alobid"'
Autor:
Ziyad Binkhathlan, Osman Yusuf, Raisuddin Ali, Abdullah H. Alomrani, Aws Alshamsan, Abdullah K. Alshememry, Aliyah Almomen, Musaed Alkholief, Ibrahim A. Aljuffali, Faleh Alqahtani, Saad Alobid, Essam A. Ali, Afsaneh Lavasanifar
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100253- (2024)
This study aimed to present findings on a paclitaxel (PTX)-loaded polymeric micellar formulation based on polycaprolactone-vitamin E TPGS (PCL-TPGS) and evaluate its in vitro anticancer activity as well as its in vivo pharmacokinetic profile in healt
Externí odkaz:
https://doaj.org/article/8cb9833838b94d969a613d2db5ef1d01
Autor:
Nadira Noushida, Roopa P. Nayak, Rokeya Sultana, Thriveni Raunak Salian, Saad Alobid, Moneer E. Almadani, Fuzail Ahmad, Rafiulla Gilkaramenthi, Syed Mohammed Basheeruddin Asdaq, Ali Ibrahim Almoteer
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 3, Pp 103100- (2024)
Background: Globally, cardiovascular disease (CVD) remains the foremost cause of mortality. Conventional medications are associated with several complications, necessitating an alternative, safe and efficacious medicine. Therefore, the study was plan
Externí odkaz:
https://doaj.org/article/ebaba55b542a41459f1398d5f3614e8c
Autor:
Pradnya V Gadhave, Guruprasad V Sutar, Sachin J Sajane, Vivekkumar K. Redasani, Kuntal Das, Dharani Prasad P, Saad Alobid, Ali Ibrahim Almoteer, Syed Imam Rabbani, Farhana Yasmin, Rafiulla Gilkaramenthi, Majidah Abdulrazaq AlAnazi, Haya Jameel Alshamrani, Syed Mohammed Basheeruddin Asdaq
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 2, Pp 101953- (2024)
Background: Polycystic ovarian syndrome (PCOS) is one of the known causes of anovulatory fertility in the world. Previous research has linked oxidative stress could contribute to PCOS, and vanillic acid has shown antioxidant potential. Hence, the pre
Externí odkaz:
https://doaj.org/article/5e236b1702e444169f98788c6b0608b4
Autor:
Anjali Nayak, Rashu Raju, Paramita Das, Kuntal Das, A. Suvitha, Biswa Ranjan Meher, Saad Alobid, Ali Ibrahim Almoteer, Moneer E. Almadani, Ahmed Alshehri, Adel Alghamdi, Fuzail Ahmad, Syed Imam Rabbani, Syed Mohammed Basheeruddin Asdaq, Naira Nayeem
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 1, Pp 101888- (2024)
Background: Alzheimer’s disease (AD) is a severe, varied, and complex brain condition that gradually impairs memory and cognitive function. Epidemiological studies have shown that patients who have a history of long-term NSAID use have a decreased
Externí odkaz:
https://doaj.org/article/e812cf9114ed47ec81d2dc7f242bebf3
Autor:
Shailaja P. Desai, S.K. Mohite, Saad Alobid, M.G. Saralaya, Ashwini S Patil, Kuntal Das, Moneer E. Almadani, Syed Arif Hussain, Bader Hussain Alamer, Ebtesam Abdulrahman Jibreel, Ali Ibrahim Almoteer, Syed Mohammed Basheeruddin Asdaq
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 12, Pp 101836- (2023)
Background and objectives: Researchers have recently focused on the biological and synthetic effects of 1, 2, and 4-triazole fused heterocyclic molecules because they have tremendous medicinal value. The objective of the present study was to carry ou
Externí odkaz:
https://doaj.org/article/0134eb33453d4ab28e5bf1815f037900
Autor:
Thiagarajan Venkatesan, Ali Alaseem, Aiyavu Chinnaiyan, Sivanesan Dhandayuthapani, Thanigaivelan Kanagasabai, Khalid Alhazzani, Priya Dondapati, Saad Alobid, Umamaheswari Natarajan, Ruben Schwartz, Appu Rathinavelu
Publikováno v:
Cells, Vol 7, Iss 5, p 41 (2018)
The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of ang
Externí odkaz:
https://doaj.org/article/b32d1e9cf99540b493245b2f3bda1b17
Autor:
Khalid Alhazzani, Thiagarajan Venkatesan, Umamaheswari Natarajan, Mohammad Algahtani, Ali Alaseem, Saad Alobid, Appu Rathinavelu
Publikováno v:
Biotechnology Letters. 44:787-801
Colorectal cancer (CRC) is the third most prevalent type of cancer in the United States. The treatment options for cancer include surgery, chemotherapy, radiation, and/or targeted therapy, which show significant improvement in overall survival. Among
Autor:
Ali Alaseem, Arkene Levy, Saad Alobid, Keerthi Thallapureddy, Appu Rathinavelu, Priya Dondapati, Khalid Alhazzani, Paramajot Kaur, Khadijah Cheema
Publikováno v:
Current Cancer Drug Targets. 19:179-188
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase, which is an essential player in regulating cell migration, invasion, adhesion, proliferation, and survival. Its overexpression and activation have been identified in sixty-eight percent o
Autor:
Thanigaivelan, Kanagasabai, Thiagarajan, Venkatesan, Umamaheswari, Natarajan, Saad, Alobid, Khalid, Alhazzani, Mohammad, Algahtani, Appu, Rathinavelu
Publikováno v:
Cellular signalling. 66
Overexpression of MDM2 oncoprotein has been detected in a large number of diverse human malignancies and has been shown to play both p53-dependent and p53-independent roles in oncogenesis. Our study was designed to explore the impact of MDM2 overexpr
Autor:
Thiagarajan Venkatesan, Saad Alobid, Mohammad Algahtani, Thanigaivelan Kanagasabai, Appu Rathinavelu, Khalid Alhazzani, Umamaheswari Natarajan
Publikováno v:
Cellular Signalling. 66:109435
Overexpression of MDM2 oncoprotein has been detected in a large number of diverse human malignancies and has been shown to play both p53-dependent and p53-independent roles in oncogenesis. Our study was designed to explore the impact of MDM2 overexpr