Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Saad, Lahlou"'
Autor:
Thayane Rebeca Alves-Santos, Odair Alves Silva, Hicla Stefany Moreira, Rosivaldo Santos Borges, Gloria Pinto Duarte, Pedro Jorges Caldas Magalhães, Saad Lahlou
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
We previously reported that trans-4-methoxy-β-nitrostyrene (T4MN) evoked higher vasorelaxant effects in small resistance arteries from spontaneously hypertensive rats (SHRs) in comparison with its parent drug, the β-nitrostyrene 1-nitro-2-phenyleth
Externí odkaz:
https://doaj.org/article/e82a105aa5884eb1a76a767375a77ce7
Autor:
Pedro Jorge Caldas Magalhães, Emanuella Feitosa de Carvalho, Saad Lahlou, Thiago Brasileiro de Vasconcelos, Teresinha Silva de Brito, Helder Veras Ribeiro-Filho
Publikováno v:
Fundamental & Clinical Pharmacology. 33:612-620
A group of nitro compounds contains a benzene ring in a short aliphatic chain with the NO2 group, property that supposedly favors its vasodilator profile. In this study, we evaluated in isolated rat aorta the effects of 1-nitro-2-propylbenzene (NPB),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76eed960918e65224decbcede7d70080
https://doi.org/10.1111/fcp.12475
https://doi.org/10.1111/fcp.12475
Autor:
Taylena Maria Teófilo, Rosivaldo S. Borges, Gloria Pinto Duarte, Pedro Jorge Caldas Magalhães, Armênio Aguiar dos Santos, Saad Lahlou
Publikováno v:
European Journal of Pharmacology. 849:154-159
Previously, we showed that the synthetic nitroderivative trans-4-methyl-β-nitrostyrene (T4MeN) induced vasorelaxant effects in rat isolated aortic rings. Here, we investigated the mechanisms underlying the cardiovascular effects of T4MeN in normoten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e60b24bc336879a8823c7feca29fa49
https://doi.org/10.1016/j.ejphar.2019.01.063
https://doi.org/10.1016/j.ejphar.2019.01.063
Autor:
Conceição da Silva Martins, Armênio Aguiar dos Santos, Saad Lahlou, Karoline Gonzaga-Costa, Marta Maria Caetano-Souza, Alfredo Augusto Vasconcelos-Silva, Rosivaldo S. Borges, Joyce Kelly R. da Silva, Pedro Jorge Caldas Magalhães, Gloria Pinto Duarte, Cássia Rodrigues Roque, Hellida Larissa Sousa-Brito
Publikováno v:
Life sciences. 275
Aims We examined the effects of treatment with 1-nitro-2-phenylethane (NP), a novel soluble guanylate cyclase stimulator, on monocrotaline (MCT)-induced PAH in rats. Main methods At day 0, male adult rats were injected with a single subcutaneous (s.c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787b69450a581f0f9cd6fa645477d40e
https://pubmed.ncbi.nlm.nih.gov/33711391
https://pubmed.ncbi.nlm.nih.gov/33711391
Autor:
Rosivaldo S. Borges, Loeste Arruda-Barbosa, Saad Lahlou, Karoline Gonzaga-Costa, Alfredo Augusto Vasconcelos-Silva, Gloria Pinto Duarte, Hellida Larissa Sousa-Brito, Pedro Jorge Caldas Magalhães
Publikováno v:
Fundamentalclinical pharmacologyReferences. 35(2)
Previously, we showed that 1-nitro-2-phenylethene, a nitrostyrene derivative of 1-nitro-2-phenylethane, induced vasorelaxant effects in rat aorta preparations. Here, we studied mechanisms underlying the vasorelaxant effects of its structural analog,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f0859097c53c2fe37190f11880566e
https://pubmed.ncbi.nlm.nih.gov/33141973
https://pubmed.ncbi.nlm.nih.gov/33141973
Autor:
Loeste Arruda-Barbosa, Rosivaldo S. Borges, Gloria Pinto Duarte, Alfredo Augusto Vasconcelos-Silva, Saad Lahlou, Pedro Jorge Caldas Magalhães
Publikováno v:
Clinical and experimental pharmacologyphysiologyREFERENCES. 48(5)
Trans-4-methoxy-β-nitrostyrene (T4MN) induced more potent vasorelaxant effects in resistance arteries from hypertensive rats than its parent drug, β-nitrostyrene 1-nitro-2-phenylethene (NPe). To better understand the influence of insertion of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b409c5963f2f1676caf465d436232c20
https://pubmed.ncbi.nlm.nih.gov/33506524
https://pubmed.ncbi.nlm.nih.gov/33506524
Autor:
Pedro Jorge Caldas Magalhães, José Geraldo de Carvalho Pereira, Paulo S. Oliveira, Thiago Brasileiro de Vasconcelos, Saad Lahlou, Helder Veras Ribeiro-Filho
Publikováno v:
European Journal of Pharmacology. 830:105-114
Compounds containing a nitro group may reveal vasodilator properties. Several nitro compounds have a NO2 group in a short aliphatic chain connected to an aromatic group. In this study, we evaluated in rat aorta the effects of two nitro compounds, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb522232fd1067f8aa8fc575b3956ba
https://doi.org/10.1016/j.ejphar.2018.04.029
https://doi.org/10.1016/j.ejphar.2018.04.029
Autor:
Gloria Pinto Duarte, Thayane Rebeca Alves-Santos, Odair Alves Silva, Saad Lahlou, Pedro Jorges Caldas Magalhães, Rosivaldo S. Borges, Hicla Stefany Moreira
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology, Vol 10 (2019)
Previously, we showed that trans-4-methoxy-β-nitrostyrene (T4MN) induced higher vasorelaxant effects in small resistance arteries from spontaneously hypertensive rats (SHRs) in comparison with its parent drug, the β-nitrostyrene 1-nitro-2-phenyleth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c1e2b847aa8ab38f9ead58f3a5943b
Autor:
Ana Carolina Migliorini Figueira, Helder Veras Ribeiro-Filho, Ivan da Rocha Pitta, Saad Lahlou, Gloria Pinto Duarte, Thayna Mendonca Avelino, Luiza A. Rabelo, Odair Alves Silva, Thais Helena Tittanegro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0aaeff3ea982e0cf40bf634fde8c64e
https://doi.org/10.1111/1440-1681.13252/v2/response1
https://doi.org/10.1111/1440-1681.13252/v2/response1
Autor:
Gloria Pinto Duarte, Ivan da Rocha Pitta, Odair Alves Silva, Thais Helena Tittanegro, Ana Carolina Migliorini Figueira, Helder Veras Ribeiro-Filho, Saad Lahlou, Thayna Mendonca Avelino, Luiza A. Rabelo
Publikováno v:
Clinical and experimental pharmacologyphysiologyREFERENCES. 47(5)
The present investigation aimed to characterize the effect of a short-time treatment with a new thiazolidinedione (TZD) derivative, GQ-130, on metabolic alterations in rats fed a high-fat diet (HFD). We investigated whether metabolic alterations indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce645ebb1744ad0245cc59e480730d3c
https://pubmed.ncbi.nlm.nih.gov/31909493
https://pubmed.ncbi.nlm.nih.gov/31909493