Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy.

Autor: Pavlidis P; School of Immunology and Microbial Sciences, King's College London, London, UK., Tsakmaki A; Diabetes Research Group, School of Life Course Sciences, Faculty of Life Science and Medicine, King's College London, London, UK., Pantazi E; School of Immunology and Microbial Sciences, King's College London, London, UK., Li K; Janssen Research & Development, 1400 McKean Rd, Spring House, PA, 19477, USA., Cozzetto D; Translational Bioinformatics, National Institute for Health Research Biomedical Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK., Digby-Bell J; School of Immunology and Microbial Sciences, King's College London, London, UK., Yang F; Janssen Research & Development, 1400 McKean Rd, Spring House, PA, 19477, USA., Lo JW; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, UK., Alberts E; School of Immunology and Microbial Sciences, King's College London, London, UK., Sa ACC; Janssen Research & Development, 1400 McKean Rd, Spring House, PA, 19477, USA., Niazi U; Translational Bioinformatics, National Institute for Health Research Biomedical Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK., Friedman J; Janssen Research & Development, 1400 McKean Rd, Spring House, PA, 19477, USA., Long AK; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Ding Y; Translational and Clinical Research Institute, Newcastle University, Framlington Place, Newcastle upon Tyne, UK., Carey CD; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Framlington Place, Newcastle upon Tyne, UK., Lamb C; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.; Translational and Clinical Research Institute, Newcastle University, Framlington Place, Newcastle upon Tyne, UK., Saqi M; Translational Bioinformatics, National Institute for Health Research Biomedical Centre, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK., Madgwick M; Earlham Institute, Norwich Research Park, Norwich, UK.; Quadram Institute Bioscience, Norwich Research Park, Norwich, UK., Gul L; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, UK.; Earlham Institute, Norwich Research Park, Norwich, UK.; Quadram Institute Bioscience, Norwich Research Park, Norwich, UK., Treveil A; Earlham Institute, Norwich Research Park, Norwich, UK.; Quadram Institute Bioscience, Norwich Research Park, Norwich, UK., Korcsmaros T; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, UK.; Earlham Institute, Norwich Research Park, Norwich, UK.; Quadram Institute Bioscience, Norwich Research Park, Norwich, UK., Macdonald TT; Centre for Immunobiology, Barts and the London School of Medicine and Dentistry, QMUL, London, UK., Lord GM; School of Immunology and Microbial Sciences, King's College London, London, UK.; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Bewick G; Diabetes Research Group, School of Life Course Sciences, Faculty of Life Science and Medicine, King's College London, London, UK., Powell N; Division of Digestive Diseases, Faculty of Medicine, Imperial College London, London, UK. npowell@ic.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 03; Vol. 13 (1), pp. 5820. Date of Electronic Publication: 2022 Oct 03.