Výsledky vyhledávání - "Saïdi M. Soudja"

Le dialogue entre les cellules souches intestinales et les lymphocytes T CD4+ module l’homéostasie des cellules souches

Publikováno v: médecine/sciences. 36:69-72

Dans le cadre d’un partenariat avec médecine/sciences, et pour la troisième année, des étudiants du module d’immunologie virologie et cancer du Master de cancérologie de Lyon présentent une analyse d’articles scientifiques récents faisan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab67feb5e8b23d202e6f96d4d967d337
https://doi.org/10.1051/medsci/2019175

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Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection

Autor: Arnauld Sergé, Mark J. McCarron, Saïdi M. Soudja, Magali Irla, Julien C. Marie

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, 2019, 10, pp.5690. ⟨10.1038/s41467-019-13456-z⟩
Nature Communications, Nature Publishing Group, 2019, 10, ⟨10.1038/s41467-019-13456-z⟩

In the thymus, the T lymphocyte repertoire is purged of a substantial portion of highly self-reactive cells. This negative selection process relies on the strength of TCR-signaling in response to self-peptide-MHC complexes, both in the cortex and med

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6b2e3a18fb5b6b1d4d4021015c77ac
https://doaj.org/article/87adb1264ac9462da662d251d3aa3047

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SMAD4 governs a feedforward regulation of the TGF-β-effects in CD8 T cells that contributes to preventing chronic intestinal inflammation

Autor: Saïdi M. Soudja, Nicolas Benech, Célia Barrachina, Ramdane Igalouzene, Emeric Dubois, Hector Hernandez-Vargas, Julien C. Marie, David Bauché

SMAD4, a key mediator of TGF-β signaling, plays a crucial role in T cells to prevent chronic gut inflammation. However, the molecular mechanisms underlying this control remain elusive. Using different genetic and epigenetic approaches, we unexpected

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::333e951c7ea98594a795e598aff52f11
https://doi.org/10.1101/2021.02.19.431987

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Le microbiote intestinal de souris, un enjeu majeur dans la reproductibilité des résultats des modèles in vivo

Autor: Saïdi M. Soudja, Benjamin Estavoyer

Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2018, 34 (6-7), pp.609-611. ⟨10.1051/medsci/20183406027⟩

Dans le cadre d’un partenariat avec médecine/sciences, et pour la seconde année, des étudiants du module d’immunologie virologie et cancer du Master de cancérologie de Lyon présentent une analyse d’articles scientifiques récents faisant �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccade88115770f1b13eb0c33e13b950
https://doi.org/10.1051/medsci/20183406027

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Le butyrate, un médiateur métabolique bactérien salutaire pour la réaction du greffon contre l’hôte

Autor: Saïdi M. Soudja, Joseph Bisaccia

Publikováno v: médecine/sciences. 33:862-864

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f096e617c34169335fa0c7514c174d3e
https://doi.org/10.1051/medsci/20173310016

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Minimal Tolerance to a Tumor Antigen Encoded by a Cancer-Germline Gene

Autor: Catherine Uyttenhove, Céline Powis de Tenbossche, Anne-Marie Schmitt-Verhulst, Francis Brasseur, Ivo J. Huijbers, Luc Pilotte, Michel Buferne, Didier Colau, Patrick Chomez, Benoît Van den Eynde, Else-Marit Inderberg-Suso, Saïdi M. Soudja

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2012, 188 (1), pp.111-21. ⟨10.4049/jimmunol.1002612⟩
Journal of Immunology, 2012, 188 (1), pp.111-21. ⟨10.4049/jimmunol.1002612⟩

Central tolerance toward tissue-restricted Ags is considered to rely on ectopic expression in the thymus, which was also observed for tumor Ags encoded by cancer-germline genes. It is unknown whether endogenous expression shapes the T cell repertoire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b838403640182700f6bc81b3045158
https://doi.org/10.4049/jimmunol.1002612

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Akademický článek

A T cell-intrinsic function for NF-κB RelB in experimental autoimmune encephalomyelitis

Autor: Guilhem Lalle, Raphaëlle Lautraite, Allison Voisin, Julie Twardowski, Pierre Stéphan, Marlène Perrin-Niquet, Ramdane Igalouzene, Saidi M. Soudja, Julien C. Marie, Marc Vocanson, Nilushi De Silva, Ulf Klein, Sankar Ghosh, Yenkel Grinberg-Bleyer

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract NF-kappaB (NF-κB) is a family of transcription factors with pleiotropic functions in immune responses. The alternative NF-κB pathway that leads to the activation of RelB and NF-κB2, was previously associated with the activation and functi

Externí odkaz: https://doaj.org/article/e703d43485cd4415ac33af46ed0a0b4b

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Epithelial-Mesenchymal-Transition-Like and TGFβ Pathways Associated with Autochthonous Inflammatory Melanoma Development in Mice

Autor: Céline Powis de Tenbossche, Benoît Van den Eynde, Anne-Marie Schmitt-Verhulst, Amandine Mas, Lionel Chasson, Saïdi M. Soudja, Grégory Verdeil, Maria Wehbe, Rodolphe R. Guinamard

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7 (11), pp.e49419. ⟨10.1371/journal.pone.0049419⟩
PLoS One, Vol. 7, no.11, p. e49419 (2012)
PLoS ONE, Vol 7, Iss 11, p e49419 (2012)
PLoS ONE, 2012, 7 (11), pp.e49419. ⟨10.1371/journal.pone.0049419⟩

We compared gene expression signatures of aggressive amelanotic (Amela) melanomas with those of slowly growing pigmented melanomas (Mela), identifying pathways potentially responsible for the aggressive Amela phenotype. Both tumors develop in mice up

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907047c0bc7af6bc8b59176d1357cf47
http://europepmc.org/articles/PMC3500287

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