T-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62.

Autor: Daniel CJ; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Pelz C; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Wang X; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Munks MW; Department of Molecular Microbiology and Immunology, School of Medicine, Oregon Health and Science University, Portland, Oregon., Ko A; Department of Molecular Microbiology and Immunology, School of Medicine, Oregon Health and Science University, Portland, Oregon., Murugan D; Department of Cell, Developmental and Cancer Biology, School of Medicine, Oregon Health and Science University, Portland, Oregon., Byers SA; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Juarez E; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Taylor KL; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Fan G; Department of Pathology, School of Medicine, Oregon Health and Science University, Portland, Oregon., Coussens LM; Department of Cell, Developmental and Cancer Biology, School of Medicine, Oregon Health and Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon., Link JM; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon., Sears RC; Department of Molecular and Medical Genetics, School of Medicine, Oregon Health and Science University, Portland, Oregon.; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2022 Jul 06; Vol. 20 (7), pp. 1151-1165.

Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and flavopiridol correlates with release of free P-TEFb from the large, inactive form of the complex.

Autor: Biglione S; Interdisciplinary Molecular and Cellular Biology Program, University of Iowa, Iowa City, IA, USA. biglione@cbrinstitute.org, Byers SA, Price JP, Nguyen VT, Bensaude O, Price DH, Maury W

Publikováno v: Retrovirology [Retrovirology] 2007 Jul 11; Vol. 4, pp. 47. Date of Electronic Publication: 2007 Jul 11.

Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186.

Autor: Li Q; Department of Biochemistry and Molecular Biology Program, University of Iowa, Iowa City, Iowa 52242, USA., Price JP, Byers SA, Cheng D, Peng J, Price DH

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2005 Aug 05; Vol. 280 (31), pp. 28819-26. Date of Electronic Publication: 2005 Jun 17.

Characterization of Cdk9(55) and differential regulation of two Cdk9 isoforms.

Autor: Shore SM; Department of Biochemistry, University of Iowa, 100 MERF Room 3130, Iowa City, IA 52242, USA., Byers SA, Dent P, Price DH

Publikováno v: Gene [Gene] 2005 Apr 25; Vol. 350 (1), pp. 51-8.

Identification of a novel isoform of Cdk9.

Autor: Shore SM; Department of Biochemistry, University of Iowa, Iowa City, IA 52242, USA., Byers SA, Maury W, Price DH

Publikováno v: Gene [Gene] 2003 Mar 27; Vol. 307, pp. 175-82.