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pro vyhledávání: '"SYNAPSIN"'
Akademický článek
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Autor:
Alexandra Stavsky, Leonardo A Parra-Rivas, Shani Tal, Jen Riba, Kayalvizhi Madhivanan, Subhojit Roy, Daniel Gitler
Publikováno v:
eLife, Vol 12 (2024)
The cytosolic proteins synucleins and synapsins are thought to play cooperative roles in regulating synaptic vesicle (SV) recycling, but mechanistic insight is lacking. Here, we identify the synapsin E-domain as an essential functional binding-partne
Externí odkaz:
https://doaj.org/article/54c49400ea3b46eb8987578b70d988d8
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1160 (2024)
Ketone bodies are considered alternative fuels for the brain when glucose availability is limited. To determine the neuroregenerative potential of D,L-sodium-beta-hydroxybutyrate (D/L-BHB), Sprague Dawley rat primary cortical neurons were exposed to
Externí odkaz:
https://doaj.org/article/1592f66336c64f4e8925806909aed626
Autor:
Ricardo Sant’Anna, Bruno K. Robbs, Júlia Araújo de Freitas, Patrícia Pires dos Santos, Annekatrin König, Tiago Fleming Outeiro, Debora Foguel
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-16 (2023)
Abstract Background Soluble oligomeric forms of alpha-synuclein (aSyn-O) are believed to be one of the main toxic species in Parkinson’s disease (PD) leading to degeneration. aSyn-O can induce Ca2+ influx, over activating downstream pathways leadin
Externí odkaz:
https://doaj.org/article/026c500fe8464bafaf7b7a9e26e9c403
Autor:
Jörn von Döhren
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionNeurodevelopment in larval stages of non-model organisms, with a focus on the serotonin- and FMRFamide-immunoreactive components, has been in the focus of research in the recent past. However, some taxonomic groups remain understudied. Ne
Externí odkaz:
https://doaj.org/article/008cbc2ac74842888c8d961cbd9fbdda
Autor:
Isabel Bünger, Ivan Talucci, Jakob Kreye, Markus Höltje, Konstantin L. Makridis, Helle Foverskov Rasmussen, Scott van Hoof, César Cordero-Gomez, Tim Ullrich, Eva Sedlin, Kai Oliver Kreissner, Christian Hoffmann, Dragomir Milovanovic, Paul Turko, Friedemann Paul, Jessica Meckies, Stefan Verlohren, Wolfgang Henrich, Rabih Chaoui, Hans Michael Maric, Angela M. Kaindl, Harald Prüss
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 33, Iss , Pp 100678- (2023)
Anti-neuronal autoantibodies can be transplacentally transferred during pregnancy and may cause detrimental effects on fetal development. It is unclear whether autoantibodies against synapsin-I, one of the most abundant synaptic proteins, are associa
Externí odkaz:
https://doaj.org/article/5cee482d828a46ee9bcb87e2a8908a06
Publikováno v:
Biology, Vol 13, Iss 1, p 35 (2024)
This article presents recent findings as regards distribution of cells producing serotonin and dopamine in the larval central nervous system at different developmental stages, including four pelagic larval stages (zoea I–IV), a semibenthic postlarv
Externí odkaz:
https://doaj.org/article/0761067149354c07943e2a93377f3607
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 5, Pp 562-568 (2022)
Objective(s): Sleep has a pivotal role in learning-memory and sleep deprivation (SD) negatively affects synaptic functioning. Cytidine-5-diphosphocholine (Citicoline) has been known to improve learning and memory functions. Our objective was to explo
Externí odkaz:
https://doaj.org/article/9e4cc7a16083410ab0ae51ab1f4d11f4
Autor:
Isabel Bünger, Konstantin L. Makridis, Jakob Kreye, Marc Nikolaus, Eva Sedlin, Tim Ullrich, Christian Hoffmann, Johannes Vincent Tromm, Helle Foverskov Rasmussen, Dragomir Milovanovic, Markus Höltje, Harald Prüss, Angela M. Kaindl
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Maternal autoantibodies can be transmitted diaplacentally, with potentially deleterious effects on neurodevelopment. Synapsin 1 (SYN1) is a neuronal protein that is important for synaptic communication and neuronal plasticity. While monoallelic loss
Externí odkaz:
https://doaj.org/article/60487b530ac44f82ab095eaf3600566c