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pro vyhledávání: '"SX09 LiverX"'
Autor:
Daniel Konrad, Thomas A. Lutz, J A Pospisilik, Stephan Wueest, L. Van Lommel, Simon M. Schultze, Julia M. Rytka, Sarah Debray, Daniel T. Meier, Frans Schuit, Katleen Lemaire, Helga Ellingsgaard, Simone Boller, O Tschopp, Sabine Rütti, U Malipiero, Jan A. Ehses, Marc Y. Donath, Peter Y. Wielinga, Harald Esterbauer, M. Böni-Schnetzler, Anica Schraenen
Publikováno v:
Diabetologia
Inflammation contributes to both insulin resistance and pancreatic beta cell failure in human type 2 diabetes. Toll-like receptors (TLRs) are highly conserved pattern recognition receptors that coordinate the innate inflammatory response to numerous
Publikováno v:
Archives of physiology and biochemistry. 117(2)
The protein kinase B (PKB) family encompasses three isoforms; PKBα (AKT1), PKBβ (AKT2) and PKBγ (AKT3). PKBα and PKBβ but not PKBγ, are prominently expressed in classical insulin-sensitive tissues like liver, muscle and fat. Transgenic mice def