Výsledky vyhledávání

Strontium Ranelate Increases Cartilage Matrix Formation

Autor: Yves Henrotin, Yannis Tsouderos, P. Galais, Alain Labasse, SX Zheng, Jean-Yves Reginster, Jean-Michel Crielaard

Publikováno v: Journal of Bone and Mineral Research. 16:299-308

Based on previous studies showing that strontium ranelate (S12911) modulates bone loss in osteoporosis, it could be hypothesized that this drug also is effective on cartilage degradation in osteoarthritis (OA). This was investigated in vitro on norma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7484ecfc0692dc64b3d94025be3503c5
https://doi.org/10.1359/jbmr.2001.16.2.299

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Modulation of human chondrocyte metabolism by recombinant human interferon

Autor: Alain Labasse, Ginette Deby, SX Zheng, Yves Henrotin, Jean-Michel Crielaard, Jean-Yves Reginster

Publikováno v: Osteoarthritis and Cartilage. 8:474-482

Interferon gamma (IFN gamma) is found to be elevated in the synovial fluid of patients with rheumatoid arthritis and osteoarthritis, suggesting its implication in joint disease pathogenesis. In this study, we investigated the effects of IFN gamma on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811a64ff8b83b2bee2c8ca52c1cc3266
https://doi.org/10.1053/joca.1999.0323

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In vitro study of the antioxidant properties of nimesulide and 4-OH nimesulide: effects on HRP- and luminol-dependent chemiluminescence produced by human chondrocytes

Autor: Yves Henrotin, Alain Labasse, A. P. Maroulis, SX Zheng, Christiane Deby, Jean-Michel Crielaard, Jean-Yves Reginster, Maurice L. Lamy, Ginette Deby-Dupont, Ange Mouithys-Mickalad

Publikováno v: Osteoarthritis and Cartilage. 8(6):419-425

Objectives Reactive oxygen species (ROS) are now recognized to play an important role in the pathogenesis of rheumatic diseases and constitute an interesting therapeutic target for drugs. This in vitro study was designed to evaluate the antioxidant p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a014bb80fa986023694791ead3475e

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High Prevalence of Low Femoral Bone Mineral Density in Elderly Women Living in Nursing Homes or Community-Dwelling: A Plausible Role of Increased Parathyroid Hormone Secretion

Autor: Christiane Gosset, SX Zheng, Jean-Yves Reginster, Adelin Albert, H Pirenne, Walthère Dewé, Julien Collette, Rita Deroisy, I Frederick

Publikováno v: Osteoporosis International. 9:121-128

The present study was designed to visit elderly women living in nursing homes and to compare their femoral neck bone mineral density (BMD) and circulating levels of parathyroid hormone (PTH) and 25-OH vitamin D (25-OHD) with those of subjects living

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01c2c5e63bcb81401007f27672f4d9a
https://doi.org/10.1007/s001980050124

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Effects of exogenous IL-1β, TNFα, IL-6, IL-8 and LIF on cytokine production by human articular chondrocytes

Autor: SX Zheng, Vincent Geenen, Alain Labasse, Donat De Groote, Jean-Yves Reginster, S Gaspar, Yves Henrotin

Publikováno v: Osteoarthritis and Cartilage. 4:163-173

Cytokines are potent regulators of the chondrocyte functions. Some of them are produced by chondrocytes and interact to regulate cartilage metabolism. In this study, we investigated the production of interleukin-1 beta (IL-1 beta), IL-6, IL-8 and leu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c82d719a9198c38e61102fd4e66b33
https://doi.org/10.1016/s1063-4584(96)80012-4

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In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR)

Autor: Jean-Yves Reginster, Yves Henrotin, SX Zheng, Carol M.T. Deby, Ginette Deby-Dupont, Maurice Lamy, A. Mouithys-Mickalad

Publikováno v: Free radical research. 33(5)

To determine the antioxidant activities of nonsteroidal anti-inflammatory drugs (NSAIDS), we examined by chemiluminescence (CL) and electron spin resonance (ESR) their scavenging properties towards lipid peroxides, hypochlorous acid and peroxynitrite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12d7e4cbea405d8216e3047a591c25
https://pubmed.ncbi.nlm.nih.gov/11200092

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Effects of three avocado/soybean unsaponifiable mixtures on metalloproteinases, cytokines and prostaglandin E2 production by human articular chondrocytes

Autor: Yves Henrotin, Alain Labasse, D. De Groote, SX Zheng, Jean-Yves Reginster, Georges Bernard Guillou, JM Jaspar

Publikováno v: Clinical rheumatology. 17(1)

The in-vitro effects of avocado and soybean unsaponifiable residues on neutral metalloproteinase activity, cytokines and prostaglandin E2 (PGE2) production by human articular chondrocytes were investigated. Avocado and soybean unsaponifiable residues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a9fc27c7aa40e988a5d772dbd155a03
https://pubmed.ncbi.nlm.nih.gov/9586676

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Increase in cytokine production (IL-1 beta, IL-6, TNF-alpha but not IFN-gamma, GM-CSF or LIF) by stimulated whole blood cells in postmenopausal osteoporosis

Autor: M. Lopez, Vincent Geenen, Adelin Albert, SX Zheng, Julien Collette, P. F. Zangerle, Y. Vrindts, Jean-Yves Reginster, Nathalie Franchimont, D. De Groote

Publikováno v: Maturitas. 26(1)

Postmenopausal osteoporosis is a progressive disorder characterized by a decreased bone mass and increased susceptibility to fractures. Several investigations have suggested that one of the mechanisms through which estrogen prevents bone loss was a m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3638c3f52c9fd3f826cb70042680b3
https://pubmed.ncbi.nlm.nih.gov/9032749

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