Zobrazeno 1 - 10
of 849
pro vyhledávání: '"SVZ"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Over the last decades, thyroid hormones (THs) signaling has been established as a key signaling cue for the proper maintenance of brain functions in adult mammals, including humans. One of the most fascinating roles of THs in the mature mammalian bra
Externí odkaz:
https://doaj.org/article/083d5417ef6c477e8500e50fdc7bc4c7
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/4bbdff0ab46747c79b2129851a8d3a0a
Autor:
Anna Lozano-Ureña, José M. Frade
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Alterations in adult neurogenesis are a common hallmark of neurodegenerative diseases. Therefore, understanding the molecular mechanisms that control this process is an indispensable requirement for designing therapeutic interventions addressing neur
Externí odkaz:
https://doaj.org/article/e1f01b21eb724f98b710b5229f3a1447
Autor:
Jemima Becker, Bin Sun, Farah Alammari, Wilfried Haerty, Keith W. Vance, Francis George Szele
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 354-376 (2023)
Summary: Long non-coding RNA (lncRNA) function is mediated by the process of transcription or through transcript-dependent associations with proteins or nucleic acids to control gene regulatory networks. Many lncRNAs are transcribed in the ventricula
Externí odkaz:
https://doaj.org/article/17282f691af14712add5aa1377cc34fb
Autor:
Vogt, Maximilian, Unnikrishnan, Madhukrishna Kolothara, Heinig, Nora, Schumann, Ulrike, Schmidt, Mirko H. H., Barth, Kathrin
The localization, expression, and physiological role of regulatory proteins in the neurogenic niches of the brain is fundamental to our understanding of adult neurogenesis. This study explores the expression and role of the E3-ubiquitin ligase, c-Cbl
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A93602
https://tud.qucosa.de/api/qucosa%3A93602/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A93602/attachment/ATT-0/
Autor:
Ting-Chun Lin, Yi-Chieh Tsai, Yun-An Chen, Tai-Horng Young, Chung-Che Wu, Yung-Hsiao Chiang, Chia-Hsin Kao, Abel Po-Hao Huang, Yi-Hua Hsu, Kai-Yun Chen, Li-Kai Tsai
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Background and purposeIntracerebral hemorrhage (ICH) enhances neurogenesis in the subventricular zone (SVZ); however, the mechanism is not fully understood. We investigated the role of brain-derived neurotrophic factor (BDNF) in post-ICH neurogenesis
Externí odkaz:
https://doaj.org/article/6a417eb602fe4bc997d37849baa5ff77
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Neural stem cells (NSCs), an invaluable source of neuronal and glial progeny, have been widely interrogated in the last twenty years, mainly to understand their therapeutic potential. Most of the studies were performed with cells derived from pluripo
Externí odkaz:
https://doaj.org/article/56ce6650dd1c4f9cae1b4fc30b79f03b
Autor:
Maximilian Vogt, Madhukrishna Kolothara Unnikrishnan, Nora Heinig, Ulrike Schumann, Mirko H. H. Schmidt, Kathrin Barth
Publikováno v:
Cells, Vol 12, Iss 19, p 2400 (2023)
The localization, expression, and physiological role of regulatory proteins in the neurogenic niches of the brain is fundamental to our understanding of adult neurogenesis. This study explores the expression and role of the E3-ubiquitin ligase, c-Cbl
Externí odkaz:
https://doaj.org/article/3ceb4a4d97404b1c8747a9f980442cc2
Autor:
Emi Takahashi, Nina Allan, Rafael Peres, Alpen Ortug, Andre J. W. van der Kouwe, Briana Valli, Elizabeth Ethier, Jacob Levman, Nicole Baumer, Keita Tsujimura, Nauru Idalia Vargas-Maya, Trevor A. McCracken, Rosa Lee, Alika K. Maunakea
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
IntroductionAutism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction, communication and repetitive, restrictive behaviors, features supported by cortical activity. Given the importance of the sub
Externí odkaz:
https://doaj.org/article/aa3b78fd3832434c8d3830acc64912aa
Autor:
Lukas P.M. Kremer, Santiago Cerrizuela, Sascha Dehler, Thomas Stiehl, Jonas Weinmann, Heike Abendroth, Susanne Kleber, Alexander Laure, Jihad El Andari, Simon Anders, Anna Marciniak-Czochra, Dirk Grimm, Ana Martin-Villalba
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 33-50 (2021)
The adult mammalian brain entails a reservoir of neural stem cells (NSCs) generating glial cells and neurons. However, NSCs become increasingly quiescent with age, which hampers their regenerative capacity. New means are therefore required to genetic
Externí odkaz:
https://doaj.org/article/20c78c1f028844548046b6a391c1e845