Characteristics of hepatitis C virus resistance in an international cohort after a decade of direct-acting antivirals

Autor: Anita Y.M. Howe, Chaturaka Rodrigo, Evan B. Cunningham, Mark W. Douglas, Julia Dietz, Jason Grebely, Stephanie Popping, Javier Alejandro Sfalcin, Milosz Parczewski, Christoph Sarrazin, Adolfo de Salazar, Ana Fuentes, Murat Sayan, Josep Quer, Midori Kjellin, Hege Kileng, Orna Mor, Johan Lennerstrand, Slim Fourati, Velia Chiara Di Maio, Vladimir Chulanov, Jean-Michel Pawlotsky, P. Richard Harrigan, Francesca Ceccherini-Silberstein, Federico Garcia, Marianne Martinello, Gail Matthews, Fay Fabián Fernando, Juan I. Esteban, Beat Müllhaupt, Julian Schulze zur Wiesch, Peter Buggisch, Christoph Neumann-Haefelin, Thomas Berg, Christoph P. Berg, Jörn M. Schattenberg, Christophe Moreno, Rudolf Stauber, Andrew Lloyd, Gregory Dore, Tanya Applegate, Juan Ignacio, Damir Garcia-Cehic, Josep Gregori, Francisco Rodriguez-Frias, Ariadna Rando, Yael Gozlan, Mario Angelico, Massimo Andreoni, Sergio Babudieri, Ada Bertoli, Valeria Cento, Nicola Coppola, Antonio Craxì, Stefania Paolucci, Giustino Parruti, Caterina Pasquazzi, Carlo Federico Perno, Elisabetta Teti, C. Vironet, Anders Lannergård, Ann-Sofi Duberg, Soo Aleman, Tore Gutteberg, Alexandre Soulier, Aurélie Gourgeon, Stephane Chevaliez, Stanislas Pol, Fabrice Carrat, Dominique Salmon, Rolf Kaiser, Elena Knopes, Perpetua Gomes, Rob de Kneght, Bart Rijnders, Mario Poljak, Maja Lunar, Rafael Usubillaga, Carole Seguin_Devaux, Enoch Tay, Caroline Wilson, Dao Sen Wang, Jacob George, Jen Kok, Ana Belén Pérez, Natalia Chueca, Miguel García-Deltoro, Ana María Martínez-Sapiña, María Magdalena Lara-Pérez, Silvia García-Bujalance, Teresa Aldámiz-Echevarría, Francisco Jesús Vera-Méndez, Juan Antonio Pineda, Marta Casado, Juan Manuel Pascasio, Javier Salmerón, Juan Carlos Alados-Arboledas, Antonio Poyato, Francisco Téllez, Antonio Rivero-Juárez, Dolores Merino, María Jesús Vivancos-Gallego, José Miguel Rosales-Zábal, María Dolores Ocete, Miguel Ángel Simón, Pilar Rincón, Sergi Reus, Alberto De la Iglesia, Isabel García-Arata, Miguel Jiménez, Fernando Jiménez, José Hernández-Quero, Carlos Galera, Mohamed Omar Balghata, Joaquín Primo, Mar Masiá, Nuria Espinosa, Marcial Delgado, Miguel Ángel von-Wichmann, Antonio Collado, Jesús Santos, Carlos Mínguez, Felícitas Díaz-Flores, Elisa Fernández, Enrique Bernal, José De Juan, José Joaquín Antón, Mónica Vélez, Antonio Aguilera, Daniel Navarro, Juan Ignacio Arenas, Clotilde Fernández, María Dolores Espinosa, María José Ríos, Roberto Alonso, Carmen Hidalgo, Rosario Hernández, María Jesús Téllez, Francisco Javier Rodríguez, Pedro Antequera, Cristina Delgado, Patricia Martín, Javier Crespo, Berta Becerril, Oscar Pérez, Antonio García-Herola, José Montero, Carolina Freyre, Concepción Grau, Joaquin Cabezas, Miguel Jimenez, Manuel Alberto Macias Rodriguez, Cristina Quilez, Maria Rodriguez Pardo, Leopoldo Muñoz-Medina, Blanca Figueruela

Publikováno v: JHEP Reports, 4(5):100462. Elsevier
Scientia

Virologic failure; Hepatitis C Fracaso virológico; Hepatitis C Fracàs virològic; Hepatitis C Background & Aims Direct-acting antiviral (DAA) regimens provide a cure in >95% of patients with chronic HCV infection. However, in some patients in whom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2145815aaad2a7dcd74da293c7ddeb
https://doi.org/10.1016/j.jhepr.2022.100462

Outcomes of Real-World Integrated HCV Microelimination for People Who Inject Drugs: An expansion of the Punjab Model

Autor: Radha K. Dhiman, Ajay Duseja, Akash Roy, Sunil Taneja, Mmphcrf Investigators, Madhumita Premkumar, Sanjeev Arora, Gagandeep Singh Grover

Publikováno v: EClinicalMedicine
EClinicalMedicine, Vol 41, Iss, Pp 101148-(2021)

Background The prevalence of chronic hepatitis C (CHC) in People Who Inject Drugs (PWID) is 8-10% as compared to 3·6% in the general population in Punjab, India. We assessed the real-world efficacy and safety of free-of-charge generic direct-acting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75aae0e46392eeae5fc474b6ba1cdf3
https://pubmed.ncbi.nlm.nih.gov/34712928

Comparison of clinical outcomes and impact of SVR in American and Chinese patients with chronic hepatitis C

Autor: Lai Wei, Robert J. Fontana, Ran Fei, Andy Lin, Anna S. Lok, Ming Yang, Huixin Liu, Bo Feng, Elizabeth Wu, Huiying Rao

Publikováno v: JHEP Reports, Vol 2, Iss 4, Pp 100136-(2020)
JHEP Reports

Background & Aims Chronic HCV infection is an important cause of hepatocellular carcinoma (HCC) and liver failure in the US but limited data are available in China. We compared the incidence of clinical outcomes among adults with chronic HCV infectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6639fdc6a82d620efca11de1204262
http://www.sciencedirect.com/science/article/pii/S2589555920300707

Limitations of non-invasive tests for assessment of liver fibrosis

Autor: Keyur Patel, Giada Sebastiani

Publikováno v: JHEP Reports

Summary The diagnostic assessment of liver injury is an important step in the management of patients with chronic liver disease (CLD). Although liver biopsy is the reference standard for the assessment of necroinflammation and fibrosis, the inherent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e37491d0184d561ec7d65b9bf64102f
http://europepmc.org/articles/PMC7047178

Using decision tree learning to predict the responsiveness of hepatitis C patients to drug treatment

Autor: Masashi Mizokami, Shigeru Takasaki, Yoshihiro Kawamura

Publikováno v: FEBS Open Bio

Highlights ► We modeled drug responses using decision tree learning based on SNPs in a genome-wide association study. ► We can predict the drug responses of a new patient with HCV genotype 1. ► Responsiveness to pegylated interferon α (PEG-IFN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f012970944b949860c7fafe83cf357a2
http://europepmc.org/articles/PMC3645974