Zobrazeno 1 - 10
of 162
pro vyhledávání: '"SVMP"'
Autor:
Rachel H. Clare, Charlotte A. Dawson, Adam Westhorpe, Laura-Oana Albulescu, Christopher M. Woodley, Nada Mosallam, Daniel J. W. Chong, Jeroen Kool, Neil G. Berry, Paul M. O’Neill, Nicholas R. Casewell
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Snakebite envenoming results in ∼100,000 deaths per year, with close to four times as many victims left with life-long sequelae. Current antivenom therapies have several limitations including high cost, variable cross-snake species efficacy and a r
Externí odkaz:
https://doaj.org/article/c67978e66f4041d2bd395e92866c736a
Autor:
Gabriela de Oliveira Almeida, Isadora Sousa de Oliveira, Eliane Candiani Arantes, Suely Vilela Sampaio
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 29 (2023)
ABSTRACT Snake venom disintegrins are low molecular weight, non-enzymatic proteins rich in cysteine, present in the venom of snakes from the families Viperidae, Crotalidae, Atractaspididae, Elapidae, and Colubridae. This family of proteins originated
Externí odkaz:
https://doaj.org/article/4e06ec9651264924843aa4ae7ff4a2c2
Akademický článek
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Autor:
Eugene Futai, Hajime Kawasaki, Shinichi Sato, Khadija Daoudi, Masafumi Hidaka, Taisuke Tomita, Tomohisa Ogawa
Publikováno v:
Toxins, Vol 15, Iss 8, p 500 (2023)
A disintegrin and metalloproteinase (ADAM) family proteins are a major class of membrane-anchored multidomain proteinases that are responsible for the shedding of cell surface protein ectodomains, including amyloid precursor protein (APP). Human ADAM
Externí odkaz:
https://doaj.org/article/3195de29ae8841c4887c17d1aefa0626
Autor:
Stefanie K. Menzies, Rachel H. Clare, Chunfang Xie, Adam Westhorpe, Steven R. Hall, Rebecca J. Edge, Jaffer Alsolaiss, Edouard Crittenden, Amy E. Marriott, Robert A. Harrison, Jeroen Kool, Nicholas R. Casewell
Publikováno v:
Toxicon: X, Vol 14, Iss , Pp 100118- (2022)
Snakebite envenoming affects more than 250,000 people annually in sub-Saharan Africa. Envenoming by Dispholidus typus (boomslang) results in venom-induced consumption coagulopathy (VICC), whereby highly abundant prothrombin-activating snake venom met
Externí odkaz:
https://doaj.org/article/57e82cdbdd8e4ac484ecefa01a32ba29
Autor:
Mátyás A. Bittenbinder, Nick D. Bergkamp, Julien Slagboom, Jan Paul M. Bebelman, Nicholas R. Casewell, Marco H. Siderius, Martine J. Smit, Jeroen Kool, Freek J. Vonk
Publikováno v:
Biology, Vol 12, Iss 6, p 765 (2023)
Snakebite envenoming is an important public health issue with devastating consequences and annual mortality rates that range between 81,000 and 138,000. Snake venoms may cause a range of pathophysiological effects affecting the nervous system and the
Externí odkaz:
https://doaj.org/article/f9e79332668545178e61ab84f5cb989e
Autor:
Eric Wachtel, Matyas A. Bittenbinder, Bas van de Velde, Julien Slagboom, Axel de Monts de Savasse, Luis L. Alonso, Nicholas R. Casewell, Freek J. Vonk, Jeroen Kool
Publikováno v:
Toxins, Vol 15, Iss 4, p 294 (2023)
The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes and may cause cytotoxic
Externí odkaz:
https://doaj.org/article/df8a65ad150346649043fa585e91e25c
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021)
Abstract Background Naja mandalayensis is a spitting cobra from Myanmar. To the best of our knowledge, no studies on this venom composition have been conducted so far. On the other hand, few envenomation descriptions state that it elicits mainly loca
Externí odkaz:
https://doaj.org/article/736ce1222d50434e8b8962a5af7c6ebe
Autor:
Kity Požek, Adrijana Leonardi, Jože Pungerčar, Weiqiao Rao, Zijian Gao, Siqi Liu, Andreas Hougaard Laustsen, Alenka Trampuš Bakija, Katarina Reberšek, Helena Podgornik, Igor Križaj
Publikováno v:
Toxins, Vol 14, Iss 4, p 232 (2022)
Disintegrin-like/cysteine-rich (DC) proteins have long been regarded just as products of proteolysis of P-III snake venom metalloproteinases (SVMPs). However, here we demonstrate that a DC protein from the venom of Vipera ammodytes (Vaa; nose-horned
Externí odkaz:
https://doaj.org/article/7ffe449b5fb14dc19502827023050548
Akademický článek
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